Results 1 to 10 of about 71,015 (314)
Peroxisome proliferator-activated receptor agonists (PPARs): a promising prospect in the treatment of psoriasis and psoriatic arthritis [PDF]
Anais Brasileiros de Dermatologia, 2013 Psoriasis is a polygenic, inflammatory and progressive disease, characterized by an abnormal differentiation and hyperproliferation of keratinocytes, associated with impaired immunologic activation and systemic disorders, while psoriatic arthritis is a ...
Emerson de Andrade Lima +5 more
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The Effector Function of Allergens
Frontiers in Allergy, 2022 Allergens are antigens that generate an IgE response (sensitization) in susceptible individuals. The allergenicity of an allergen can be thought of in terms of its ability to sensitize as well as its ability to cross-link IgE/IgE receptor complexes on ...
Stéphane Hazebrouck +2 more
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Anaesthetic Management of Myasthenia Gravis with Thymic Mass in Facial Trauma [PDF]
The Indian Anaesthetists' Forum, 2010 Myasthenia gravis is an immunologic disorder characterised by polyclonal antibodies directed against nicotinic acetylcholine receptors at postneuromuscular junction.
Deepak Sharma, Dheer Singh
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HLA-G: An Important Mediator of Maternal-Fetal Immune-Tolerance
Frontiers in Immunology, 2021 Maternal-fetal immune-tolerance occurs throughout the whole gestational trimester, thus a mother can accept a genetically distinct fetus without immunological aggressive behavior.
Baimei Zhuang +4 more
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Frontiers in Immunology, 2017 The gut microbiota is essential for the development and regulation of the immune system and the metabolism of the host. Germ-free animals have altered immunity with increased susceptibility to immunologic diseases and show metabolic alterations. Here, we
Martina Spiljar +5 more
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Allergy Takes its Toll: The Role of Toll-like Receptors in Allergy Pathogenesis
World Allergy Organization Journal, 2008 Reduced early microbial exposure in early life has become a leading candidate to explain the escalating rate of allergic disease and has generated intense interest in the interaction between the developing immune system and the microbial environment ...
Susan L. Prescott, MD, PhD, FRACP
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Toll‐like receptors in pathogenesis of neurodegenerative diseases and their therapeutic potential
Immunity, Inflammation and Disease, 2023 Toll‐like receptors (TLRs) are a family of pattern‐recognition receptors triggered by pathogen‐derived and tissue‐damage‐related ligands. TLRs were previously believed to only be expressed in immune cells.
Yosef Tsegaye Dabi +2 more
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Purinergic Regulation of Neutrophil Function
Frontiers in Immunology, 2018 Purinergic signaling, which utilizes nucleotides (particularly ATP) and adenosine as transmitter molecules, plays an essential role in immune system. In the extracellular compartment, ATP predominantly functions as a pro-inflammatory molecule through ...
Xu Wang, Deyu Chen
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, 1989 The removal of neutrophils and their histotoxic contents from the inflamed site is a prerequisite for resolution of tissue injury, and a point at which factors critical to the pathogenesis of chronic inflammation may act.
Savill, John S +5 more
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Eplet mismatch analysis in kidney transplantation: from concept to clinical practice
Clinical Transplantation and ResearchEplet mismatch analysis offers a refined approach to assessing donor-recipient compatibility in kidney transplantation, surpassing conventional antigen-level human leukocyte antigen (HLA) matching in predicting immunologic outcomes.
Hyeyoung Lee, Eun-Jee Oh
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