Results 21 to 30 of about 113,576 (312)
Anaesthetic Management of Myasthenia Gravis with Thymic Mass in Facial Trauma [PDF]
The Indian Anaesthetists' Forum, 2010 Myasthenia gravis is an immunologic disorder characterised by polyclonal antibodies directed against nicotinic acetylcholine receptors at postneuromuscular junction.
Deepak Sharma, Dheer Singh
doaj
HLA-G: An Important Mediator of Maternal-Fetal Immune-Tolerance
Frontiers in Immunology, 2021 Maternal-fetal immune-tolerance occurs throughout the whole gestational trimester, thus a mother can accept a genetically distinct fetus without immunological aggressive behavior.
Baimei Zhuang +4 more
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Frontiers in Immunology, 2017 The gut microbiota is essential for the development and regulation of the immune system and the metabolism of the host. Germ-free animals have altered immunity with increased susceptibility to immunologic diseases and show metabolic alterations. Here, we
Martina Spiljar +5 more
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Allergy Takes its Toll: The Role of Toll-like Receptors in Allergy Pathogenesis
World Allergy Organization Journal, 2008 Reduced early microbial exposure in early life has become a leading candidate to explain the escalating rate of allergic disease and has generated intense interest in the interaction between the developing immune system and the microbial environment ...
Susan L. Prescott, MD, PhD, FRACP
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Toll‐like receptors in pathogenesis of neurodegenerative diseases and their therapeutic potential
Immunity, Inflammation and Disease, 2023 Toll‐like receptors (TLRs) are a family of pattern‐recognition receptors triggered by pathogen‐derived and tissue‐damage‐related ligands. TLRs were previously believed to only be expressed in immune cells.
Yosef Tsegaye Dabi +2 more
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Liver Research, 2023 Alcohol-related liver disease (ALD) became an important health issue worldwide. Following chronic alcohol consumption, the development of ALD might be caused by metabolic and immunologic factors, such as reactive oxygen species (ROS) and pro-inflammatory
Tom Ryu +4 more
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Combination immunotherapy induces distinct T-cell repertoire responses when administered to patients with different malignancies. [PDF]
, 2020 BackgroundCTLA-4 blockade with ipilimumab is Food and Drug Administration-approved for melanoma as a monotherapy and has been shown to modulate the circulating T-cell repertoire.
Cham, Jason +7 more
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The Immunology of Hormone Receptor Positive Breast Cancer [PDF]
Frontiers in Immunology, 2021 Immune checkpoint blockade (ICB) has revolutionized the treatment of cancer patients. The main focus of ICB has been on reinvigorating the adaptive immune response, namely, activating cytotoxic T cells. ICB has demonstrated only modest benefit against advanced breast cancer, as breast tumors typically establish an immune suppressive tumor ...
Jonathan Goldberg +22 more
openaire +3 more sources
Purinergic Regulation of Neutrophil Function
Frontiers in Immunology, 2018 Purinergic signaling, which utilizes nucleotides (particularly ATP) and adenosine as transmitter molecules, plays an essential role in immune system. In the extracellular compartment, ATP predominantly functions as a pro-inflammatory molecule through ...
Xu Wang, Deyu Chen
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Anaphylatoxins spark the flame in early autoimmunity
Frontiers in Immunology, 2022 The complement system (CS) is an ancient and highly conserved part of the innate immune system with important functions in immune defense. The multiple fragments bind to specific receptors on innate and adaptive immune cells, the activation of which ...
Jovan Schanzenbacher +3 more
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