Results 21 to 30 of about 636,775 (308)
Late-onset myasthenia gravis: Is it a different clinical entity?
Neurological Sciences and Neurophysiology, 2021 Objective: The increase in the average life expectancy of humans has resulted in an increased occurrence of late-onset myasthenia gravis (LOMG). It is noticeable that the clinical, immunologic, and prognostic features of patients with LOMG are different ...
Hulya Tireli +2 more
doaj +1 more source
Topological and Structural Plasticity of the Single Ig Fold and the Double Ig Fold Present in CD19
Biomolecules, 2021 The Ig fold has had a remarkable success in vertebrate evolution, with a presence in over 2% of human genes. The Ig fold is not just the elementary structural domain of antibodies and TCRs, it is also at the heart of a staggering 30% of immunologic cell ...
Philippe Youkharibache
doaj +1 more source
Potentiation of glycine-gated NR1/NR3A NMDA receptors relieves Ca2+-dependent outward rectification [PDF]
, 2010 Glycine has diverse functions within the mammalian central nervous system. It inhibits postsynaptic neurons via strychnine-sensitive glycine receptors (GlyRs) and enhances neuronal excitation through co-activation of N-methyl-D-aspartate (NMDA) receptors.
Betz, H. +11 more
core +1 more source
Effects of Parathyroid Hormone on Immune Function
Clinical and Developmental Immunology, 2010 Parathyroid hormone (PTH) function as immunologic mediator has become interesting with the recent usage of PTH analogue (teriparatide) in the management of osteoporosis.
Abdallah Sassine Geara +7 more
doaj +1 more source
Frontiers in Genetics, 2021 The coronavirus disease 2019 (COVID-19) pandemic, induced by the pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly all over the world. There is considerable variability among neonates, children, and adults in the
Bangrong Cao +4 more
doaj +1 more source
Modulation of neurosteroid potentiation by protein kinases at synaptic- and extrasynaptic-type GABAA receptors. [PDF]
, 2015 GABAA receptors are important for inhibition in the CNS where neurosteroids and protein kinases are potent endogenous modulators. Acting individually, these can either enhance or depress receptor function, dependent upon the type of neurosteroid or ...
Adams, JM +5 more
core +1 more source
High-throughput Sequencing Based Immune Repertoire Study during Infectious Disease
Frontiers in Immunology, 2016 The selectivity of the adaptive immune response is based on the enormous diversity of T and B cell antigen-specific receptors. The immune repertoire, the collection of T and B cells with functional diversity in the circulatory system at any given time ...
Dongni Hou +4 more
doaj +1 more source
Pharmaceuticals, 2023 Metal ions are irreplaceable in many biological processes. They are components of numerous metalloproteins and serve as cofactors or structural elements for enzymes.
Klaudia Szczerba, Kamila Stokowa-Soltys
doaj +1 more source
Toll-like receptors in control of immunological autophagy [PDF]
Cell Death & Differentiation, 2009 Autophagy is a cell biological process, enabling cells to autodigest their own cytosol when starved, remove cytoplasmic protein aggregates too large for proteasomal degradation, eliminate aberrant or over-proliferated organelles, and sanitize the cytoplasm by killing intracellular microbes.
M A, Delgado, V, Deretic
openaire +2 more sources
Opioids and Their Receptors [PDF]
, 2020 The interest in opioids such as morphine, the prototypical opioid ligand, has been maintained through the years. The identification of endogenous opioids and their receptors (mu, delta, kappa, and nociceptin), molecular cloning, and the elucidation of ...
core +1 more source