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Myasthenia gravis [PDF]

Nature Reviews Disease Primers, 2019
ZusammenfassungDie Myasthenia gravis (MG) beruht auf einer durch Autoantikörper (Ak) gegen Acetylcholinrezeptoren (AChR) bzw. andere Strukturproteine der neuromuskulären Endplatte verursachten neuromuskulären Überleitungsstörung mit vorzeitiger Erschöpfbarkeit und teils manifesten Paresen einschließlich der bulbären und okulären Muskulatur. Während die
Wolfgang, Müllges, Guido, Stoll
  +9 more sources

Assessment of the risks of a myasthenic crisis after thymectomy in patients with myasthenia gravis: a systematic review and meta-analysis of 25 studies

Journal of Cardiothoracic Surgery, 2020
Background Despite the burgeoning literature describing preoperative and postoperative risks of a myasthenic crisis after thymectomy (MCAT) in patients with myasthenia gravis, substantial differences exist in the risk factors identified by previous ...
Chaoying Liu, Peng Liu, Xiao jing Zhang, Wen qian Li, Guoyan Qi   +4 more
doaj   +1 more source

Identification of Potential Serum Protein Biomarkers in Thymoma with Myasthenia Gravis After Docetaxel Treatment

Neurology and Therapy, 2023
Introduction Myasthenia gravis (MG) is a devastating acquired autoimmune disease that can seriously affect the patient’s quality of life. It is also a common complication of thymoma.
Hongxia Yang, Guoyan Qi, Huimin Dong, Ze Liu, Mei Ma, Peng Liu   +5 more
doaj   +1 more source

Metagenome-wide association study of gut microbiome revealed potential microbial marker set for diagnosis of pediatric myasthenia gravis

BMC Medicine, 2021
Background Myasthenia gravis (MG) is an acquired immune-mediated disorder of the neuromuscular junction that causes fluctuating skeletal muscle weakness and fatigue. Pediatric MG and adult MG have many different characteristics, and current MG diagnostic
Peng Liu, Yiqi Jiang, Shanshan Gu, Yinping Xue, Hongxia Yang, Yongzhao Li, Yaxuan Wang, Congya Yan, Pei Jia, Xiaoting Lin, Guoyan Qi   +10 more
doaj   +1 more source

Myasthenia Gravis

Autoimmunity, 2004
Myasthenia gravis is a disorder of neuromuscular transmission, manifest by variable weakness of skeletal muscle. The disorder has a range of therapies that differ with respect to efficacy, timing, and side effects. The physician treating myasthenia gravis must be well versed in understanding the evidence basis for using these agents, as well as the ...
Vincent, A, Rothwell, P
openaire   +5 more sources

Anxiety and depression in thymoma patients in China before surgery

Journal of Cardiothoracic Surgery, 2022
Background The study's goal was to investigate the percentage of anxiety and depression in Chinese thymoma patients before surgery, and also the factors that influence it.
Jiaduo Li, Guoyan Qi, Yaling Liu
doaj   +1 more source

Myasthenia Gravis [PDF]

New England Journal of Medicine, 1978
The basic abnormality in myasthenia gravis (MG) is a reduction in acetylcholine receptors (AChRs) at neuromuscular junctions due to the effects of autoantibodies that are directed against the AChRs in most patients, or against neighboring proteins involved in the clustering of AChRs (MuSK, LRP-4, or agrin).
openaire   +3 more sources

Clinical characteristics and outcome predictors of a Chinese childhood-onset myasthenia gravis cohort

Frontiers in Pediatrics, 2022
Myasthenia gravis is an organ-specific autoimmune disease. Currently there is no universal guidelines for childhood-onset myasthenia gravis, therefore, treatment strategies are usually based on the guidelines from adult myasthenia gravis patients.
Lifen Yang, Yulin Tang, Fang He, Ciliu Zhang, Miriam Kessi, Jing Peng, Fei Yin   +6 more
doaj   +1 more source

Meta-analysis of subxiphoid approach versus lateral approach for thoracoscopic Thymectomy

Journal of Cardiothoracic Surgery, 2020
Background Compared with traditional open surgery for thymectomy, video-assisted thoracoscopic surgery (VATS) reduces hospital stay, decreases postoperative pain, and recovers faster. VATS has become increasingly popular in the past decade.
Jiaduo Li, Guoyan Qi, Yaling Liu, Xuguang Zheng, Xiaohe Zhang   +4 more
doaj   +1 more source

Is chest tube drainage necessary after subxiphoid thoracoscopic thymectomy?

Journal of Cardiothoracic Surgery, 2020
Background Subxiphoid thoracoscopic thymectomy has been increasingly performed in recent years. This study aimed to assess the differences in outcomes between subxiphoid thoracoscopic thymectomy with and without chest tube drainage.
Jiaduo Li, Guoyan Qi, Xiaohe Zhang, Xuguang Zheng   +3 more
doaj   +1 more source