Results 31 to 40 of about 31,308 (159)

Amifampridine phosphate in the treatment of muscle-specific kinase myasthenia gravis: a phase IIb, randomized, double-blind, placebo-controlled, double crossover study

SAGE Open Medicine, 2018
Objective: The aim of this study is to determine the safety and the efficacy of amifampridine phosphate in muscle-specific kinase antibody-positive myasthenia gravis, in a 1:1 randomized, double-blind, placebo-controlled, switchback, double crossover ...
Silvia Bonanno, Maria Barbara Pasanisi, Rita Frangiamore, Lorenzo Maggi, Carlo Antozzi, Francesca Andreetta, Angela Campanella, Greta Brenna, Lorenzo Cottini, Renato Mantegazza   +9 more
doaj   +1 more source

Intrapericardial Thymoma Presented as Pericardial Tamponade with Post-Operative Myasthenia Gravis

Medicina, 2022
Background: Thymoma is an epithelial mass arising from the thymus. Most thymomas are located in the anterior mediastinum. Ectopic intrapericardial thymoma is very unusual; to date, only eight cases of pericardial thymoma have been reported. Among thymoma
Yueh-Hsun Tsai, Kai-Hsiung Ko, Hao Yen, Tsai-Wang Huang   +3 more
doaj   +1 more source

Epidemiological evidence for a hereditary contribution to myasthenia gravis: a retrospective cohort study of patients from North America

BMJ Open, 2020
Objectives To approximate the rate of familial myasthenia gravis and the coexistence of other autoimmune disorders in the patients and their families.Design Retrospective cohort study.Setting Clinics across North America.Participants The study included ...
Joel Oger, Joshua D Green, Bryan J Traynor, Richard J Barohn, Michael Benatar, Emanuela Bartoccion, Derrick Blackmore, Vinay Chaudhry, Manisha Chopra, Andrea Corse, Mazen M Dimachkie, Amelia Evoli, Julaine Florence, Miriam Freimer, James F Howard, Theresa Jiwa, Henry J Kaminski, John T Kissel, Wilma J Koopman, Bernadette Lipscomb, Michelanglo Maestri, Mariapaola Marino, Janice M Massey, April McVey, Michelle M Mezei, Srikanth Muppidi, Michael W Nicolle, Robert M Pascuzzi, Mamatha Pasnoor, Alan Pestronk, Carlo Provenzano, Roberta Ricciardi, David P Richman, Julie Rowin, Donald B Sanders, Zaeem Siddiqi, Aimee Soloway, Gil I Wolfe, Charlie Wulf, Daniel B Drachman   +39 more
doaj   +1 more source

Muscle-Specific Tyrosine Kinase-Associated Myasthenia Gravis: A Neuromuscular Surprise

Case Reports in Neurological Medicine, 2021
Myasthenia gravis is a neuromuscular autoimmune disease that results in skeletal muscle weakness that worsens after periods of activity and improves after rest.
Hassam Ali, Rahul Pamarthy, Nayab Ahsan, null WashmaAwan, Shiza Sarfraz   +4 more
doaj   +1 more source

Serum fibrinogen is not elevated in patients with myasthenia gravis

Scientific Reports
Myasthenia gravis (MG) is an autoimmune, autoantibody-mediated disease characterized by fatigable weakness of skeletal muscles. MG is a heterogeneous disease that currently lacks a robust biomarker for diagnosing all subtypes.
Taylor A. Bauman, Sean M. Lee, Vern C. Juel, Yingkai Li, Karli Gilbert, Jiaxin Chen, Henry J. Kaminski, Linda L. Kusner, MGNet Investigators   +8 more
doaj   +1 more source

Myasthenia gravis as one of paraneoplastic neurological syndromes associated with small cell lung cancer. Case report

Neurologijos seminarai, 2018
Myasthenia gravis associated with extrathymic malignancies is a rarely diagnosed pathology in clinical practice. We report a case of myasthenia gravis-like syndrome associated with small cell lung cancer.
R. Bunevičiūtė , R. Masaitienė , A. Klimašauskienė   +2 more
doaj   +1 more source

Chest CT tomography vs. intracavitary electrocardiogram guidance in predicting the length of PICC placement

BMC Surgery, 2022
Background To evaluate chest computed tomography (CT) compared to intracavitary electrocardiogram (ECG) in predicting the length of peripherally inserted central catheter (PICC) placement and analyzing the accuracy of the positioning methods.
Huimin Dong, Yuxin Zhu, Xin Zhang, Xinxin Yin, Fude Liu   +4 more
doaj   +1 more source

Illness perception characteristics and influencing factors in adult patients with myasthenia gravis in China

Brain and Behavior, 2022
Objective We aimed to examine the illness perception characteristics of patients with myasthenia gravis and analyze the associated factors. Methods A general information questionnaire, Illness Perception Questionnaire, and Simplified Coping Style ...
Le Xu, Xia Wang, Yafeng Cui, Yanghua Tian, Nong Zhou, Juanjuan Zhang, Hiaxia Ji, Xiumei Cheng, Qin Zhang, Qingfeng Li, Panpan Hu, Long Zhang   +11 more
doaj   +1 more source

Outcomes after major surgery in patients with myasthenia gravis: A nationwide matched cohort study.

PLoS ONE, 2017
ObjectiveTo validate the comprehensive features of adverse outcomes after surgery for patients with myasthenia gravis.MethodsUsing reimbursement claims from Taiwan's National Health Insurance Research Database, we analyzed 2290 patients who received ...
Yi-Wen Chang, Yi-Chun Chou, Chun-Chieh Yeh, Chaur-Jong Hu, Chih-Jen Hung, Chao-Shun Lin, Ta-Liang Chen, Chien-Chang Liao   +7 more
doaj   +1 more source

Exploring the depths of IgG4: insights into autoimmunity and novel treatments

Frontiers in Immunology
IgG4 subclass antibodies represent the rarest subclass of IgG antibodies, comprising only 3-5% of antibodies circulating in the bloodstream. These antibodies possess unique structural features, notably their ability to undergo a process known as fragment-
Selen Ünlü, Selen Ünlü, Blanca G. Sánchez Navarro, Elif Cakan, Daniel Berchtold, Rafael Meleka Hanna, Secil Vural, Secil Vural, Atay Vural, Atay Vural, Andreas Meisel, Miriam L. Fichtner, Miriam L. Fichtner   +12 more
doaj   +1 more source