Results 11 to 20 of about 61,118 (253)

Myasthenia gravis

open access: yesThe Lancet, 2001
Myasthenia gravis is an autoimmune disorder mainly caused by antibodies to the muscle acetylcholine receptors (AChRs) at the neuromuscular junction. Loss of these receptors leads to a defect in neuromuscular transmission with muscle weakness and fatigue.
Vincent, A, Palace, J, Hilton-Jones, D
openaire   +4 more sources

Myasthenia Gravis [PDF]

open access: yesNew England Journal of Medicine, 1978
The basic abnormality in myasthenia gravis (MG) is a reduction in acetylcholine receptors (AChRs) at neuromuscular junctions due to the effects of autoantibodies that are directed against the AChRs in most patients, or against neighboring proteins involved in the clustering of AChRs (MuSK, LRP-4, or agrin).
openaire   +3 more sources

Clinical characteristics and outcome predictors of a Chinese childhood-onset myasthenia gravis cohort

open access: yesFrontiers in Pediatrics, 2022
Myasthenia gravis is an organ-specific autoimmune disease. Currently there is no universal guidelines for childhood-onset myasthenia gravis, therefore, treatment strategies are usually based on the guidelines from adult myasthenia gravis patients.
Lifen Yang   +6 more
doaj   +1 more source

A phase 3 multicenter, prospective, open-label efficacy and safety study of immune globulin (human) 10% caprylate/chromatography purified in patients with myasthenia gravis exacerbations [PDF]

open access: yes, 2019
Background: Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission. Exacerbations may involve increasing bulbar weakness and/or sudden respiratory failure, both of which can be critically disabling.
Ayguasanosa, J   +17 more
core   +2 more sources

Is chest tube drainage necessary after subxiphoid thoracoscopic thymectomy?

open access: yesJournal of Cardiothoracic Surgery, 2020
Background Subxiphoid thoracoscopic thymectomy has been increasingly performed in recent years. This study aimed to assess the differences in outcomes between subxiphoid thoracoscopic thymectomy with and without chest tube drainage.
Jiaduo Li   +3 more
doaj   +1 more source

T-lymphocyte-rich thymoma and myasthenia gravis in a Siberian tiger (Panthera tigris altaica) [PDF]

open access: yes, 2014
A 10-year-old captive male Siberian tiger (Panthera tigris altaica) presented with acute onset collapse, vomiting and dyspnoea, preceded by a 6-month period of progressive muscle wasting.
A. Routh   +31 more
core   +1 more source

Meta-analysis of subxiphoid approach versus lateral approach for thoracoscopic Thymectomy

open access: yesJournal of Cardiothoracic Surgery, 2020
Background Compared with traditional open surgery for thymectomy, video-assisted thoracoscopic surgery (VATS) reduces hospital stay, decreases postoperative pain, and recovers faster. VATS has become increasingly popular in the past decade.
Jiaduo Li   +4 more
doaj   +1 more source

Relationship between hearing function and myasthenia gravis: a contemporary review [PDF]

open access: yes, 2016
There is increasing evidence of a connection between hearing function and myasthenia gravis (MG). Studies of the pathophysiological basis of this relationship suggest that acetylcholine receptors (AChRs) on outer hair cells (OHCs) play a central role. In
ALTISSIMI, Giancarlo   +5 more
core   +1 more source

A practical approach to the patient presenting with dropped head [PDF]

open access: yes, 2016
Head drop, or having a dropped head, is an uncommon condition in which patients present with a disabling inability to lift their head. It may arise in many neurological conditions that can be divided into those with neuromuscular weakness of neck ...
Demicoli, Marija, Marsh, Eleanor A.
core   +1 more source

Effect of Fufang Huangqi Decoction on the Gut Microbiota in Patients With Class I or II Myasthenia Gravis

open access: yesFrontiers in Neurology, 2022
ObjectiveTo investigate the effect of Fufang Huangqi Decoction on the gut microbiota in patients with class I or II myasthenia gravis (MG) and to explore the correlation between gut microbiota and MG (registration number, ChiCTR2100048367; registration ...
Yanghong Chen   +9 more
doaj   +1 more source

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