Results 11 to 20 of about 52,744 (222)

Statin-associated weakness in myasthenia gravis: a case report [PDF]

Journal of Medical Case Reports, 2010
Introduction Myasthenia gravis is a commonly undiagnosed condition in the elderly. Statin medications can cause weakness and are linked to the development and deterioration of several autoimmune conditions, including myasthenia gravis.
Keogh Michael J, Findlay John M, Leach Simon, Bowen John   +3 more
doaj   +3 more sources

Chronic mimics of myasthenia gravis: a retrospective case series [PDF]

, 2023
Myasthenia gravis often presents a diagnostic challenge and may be misdiagnosed, particularly in seronegative disease with active symptoms. We retrospectively evaluated 61 patients following the introduction of single fibre electromyography at our ...
Winkel, Antony, Barton, Joshua, Harrison, Patrick, Patrick Harrison, Antony Winkel, Joshua Barton   +5 more
core   +1 more source

Clinical and therapeutic features of myasthenia gravis in adults based on age at onset [PDF]

, 2020
Objective: To describe the characteristics of patients with very-late-onset myasthenia gravis (MG). Methods: This observational cross-sectional multicenter study was based on information in the neurologist-driven Spanish Registry of Neuromuscular ...
Ramos Fransi, Alba, Álvarez Velasco, Rodrigo, Casasnovas, Carlos, Pardo, Julio, Sevilla, Teresa, Et al., Cortés Vicente, Elena, Paradas, Carmen, Guerrero Sola, Antonio, Segovia, Sonia, Gallardo, Eduard, Vélez-Gómez, Beatriz, García-Sobrino, Tania, Martín Ruiz, Asunción, Martín, María Asunción, Cortés-Vicente, Elena, Ramos-Fransi, Alba, Jericó, Ivonne, Albertí, María Antonia, Pelayo-Negro, Ana L., López de Munain, Adolfo, Fernández-Torrón, Roberto, Galán, Lucía, Rojas-García, Ricard, Lozano-Veintimilla, Ana, Galan, Luciía, Lopez-de-Munain, Adolfo, Illa, Isabel, Mendoza, María Dolores, Cano-Abascal, Ángel, Gutiérrez-Gutiérrez, Gerardo, Guerrero-Sola, Antonio, Pelayo-Negro, Ana Lara, Velez, Beatriz, Gómez, María Teresa, Díaz-Manera, Jordi, Álvarez-Velasco, Rodrigo, Martínez-Piñeiro, Alicia, Moris, Germán, Querol, Luis   +39 more
core   +2 more sources

Antibodies to acetylcholine receptor in parous women with myasthenia: evidence for immunization by fetal antigen [PDF]

, 2002
The weakness in myasthenia gravis (MG) is mediated by autoantibodies against adult muscle acetylcholine receptors (AChR) at the neuromuscular junction; most of these antibodies also bind to fetal AChR, which is present in the thymus.
Wilcox, Nick, Stott, David, Vincent, Angela, Beeson, David, Matthews, Ian, Sims, Gary, Ledwidge, Serena   +6 more
core   +1 more source

Fatigue and Muscle Atrophy in a Mouse Model of Myasthenia Gravis Is Paralleled by Loss of Sarcolemmal nNOS [PDF]

, 2012
Myasthenia Gravis (MG) patients suffer from chronic fatigue of skeletal muscles, even after initiation of proper immunosuppressive medication. Since the localization of neuronal nitric oxide synthase (nNOS) at the muscle membrane is important for ...
Meinen, Sarina, Sarina Meinen, Shuo Lin, Lin, Shuo, Rüegg, Markus A., Markus A Rüegg, Punga, Anna Rostedt, Anna Rostedt Punga, Meinen Sarina, Meinen S, Lin S, Punga AR, Rüegg MA, Rueegg, Markus A., Lin Shuo, Punga Anna Rostedt, Rüegg Markus A.   +16 more
core   +2 more sources

Myasthenia Gravis and Thymoma. [PDF]

Muscle Nerve
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Claytor B, Delasos L, Raymond DP, Seroogy E, Lempel J, Li Y.   +5 more
europepmc   +2 more sources

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

Impact of SARS-CoV-2 infection on patients with myasthenia gravis: a retrospective study in a Chinese population

Frontiers in Neurology
Background and purposeMyasthenia gravis (MG) is characterized by fluctuating muscle weakness due to immune-mediated damage to acetylcholine receptors. Viral infections can exacerbate symptoms of muscle weakness, and the clinical status of patients with ...
Peng Liu, Peng Liu, Mengna Li, Liqing Li, Wenli Jia, Huimin Dong, Guoyan Qi, Guoyan Qi, Guoyan Qi   +8 more
doaj   +1 more source

Case report: Efgartigimod combined with intravenous methylprednisolone in a case of co-occurrence of unexplained myasthenia gravis, inflammatory myopathy, and fulminant myocarditis

Frontiers in Immunology
The co-occurrence of myasthenia gravis (MG), inflammatory myopathy (IM), and fulminant myocarditis (FM) has rarely been reported. The few previous articles were mostly case reports or small sample data analysis, and the etiology was mostly attributed to ...
Hongxia Yang, Zulin Pan, Ying Yang, Yaxuan Wang, Biqi Cheng, Guoyan Qi   +5 more
doaj   +1 more source

Docetaxel/cisplatin therapy in myasthenia gravis with hypertension/diabetes

Open Medicine, 2017
Therapeutic options for thymoma-associated myasthenia gravis (MG) patients complicated with hypertension and/or diabetes post thymectomy are often conventional steroids. As the prevalence of diabetes and hypertension globally increases, other therapeutic
Qi Guoyan, Xue Yinping, Li Yongzhao, Yang Hongxia, Zhang Xiaojing   +4 more
doaj   +1 more source