Results 1 to 10 of about 124,770 (168)
VEGF controls microglial phagocytic response to amyloid-β
Frontiers in Cellular Neuroscience, 2023 Microglial cells are well known to be implicated in the pathogenesis of Alzheimer’s disease (AD), due to the impaired clearance of amyloid-β (Aβ) protein.
Priscille de Gea +9 more
doaj +1 more source
Frontiers in Immunology, 2022 Autoantibodies (Abs) are biomarkers for many disease conditions and are increasingly used to facilitate diagnosis and treatment decisions. To guarantee high sensitivity and specificity, the choice of their detection method is crucial.
Christian P. Moritz +29 more
doaj +1 more source
Autoantibodies against complement factor B in rheumatoid arthritis
Frontiers in Immunology, 2023 Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder affecting the joints. Many patients carry anti-citrullinated protein autoantibodies (ACPA).
Alexandra T. Matola +12 more
doaj +1 more source
Autoantibodies predict type 1 diabetes after gestational diabetes – a 23-year cohort study
Frontiers in Endocrinology, 2023 ObjectiveTo study the predictive value of autoantibodies for type 1 (T1DM) and type 2 (T2DM) diabetes morbidity after gestational diabetes (GDM) in a 23-year follow-up study.DesignProspective population-based cohort study.MethodsWe studied 391 women with
Kaisu Luiro +13 more
doaj +1 more source
The significance of preclinical anti-BP180 autoantibodies
Frontiers in Immunology, 2022 Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease. Although the pathomechanism of BP onset has yet to be elucidated in detail, BP autoantibodies targeting two hemidesmosomal components, BP180 and BP230, are known to ...
Yosuke Mai +3 more
doaj +1 more source
World Allergy Organization Journal, 2023 Background: Autoimmune IgG response has been described in the pathogenesis of asthma in adults, but IgE autoimmunity has been little explored. Considering high levels of blood eosinophils and immunoglobulin E in asthmatic patients, the possibility of IgE
Jorge Sánchez, MD, MSc, EAC, PhD +4 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2023 Autoantibodies targeting epitopes contained within the intracellular domain (IC) of the protein phosphatase-like islet antigen 2 (IA-2) are a common marker of autoimmune type 1 diabetes (T1D), however the isolation of genuine, serum derived anti-IA-2 ...
Thilini Mendis +4 more
doaj +1 more source
Angiotensin type-1 receptor and ACE2 autoantibodies in Parkinson´s disease
npj Parkinson's Disease, 2022 The role of autoimmunity in neurodegeneration has been increasingly suggested. The renin-angiotensin system (RAS) autoantibodies play a major role in several peripheral inflammatory processes.
Carmen M. Labandeira +8 more
doaj +1 more source
Lymphocytotoxic Autoantibodies [PDF]
, 2007 Anti-lymphocytic antibodies (anti-LCA) are detected in patients with systemic lupus erythematosus (SLE) with a prevalence ranging from 60–90%. LCA detection is associated with nephritis and neurologic disorders in these patients, and high rates of LCA occur during phases of active SLE.
Renaudineau, Yves +2 more
openaire +2 more sources
Increased immune complexes of hypocretin autoantibodies in narcolepsy. [PDF]
PLoS ONE, 2010 BACKGROUND: Hypocretin peptides participate in the regulation of sleep-wake cycle while deficiency in hypocretin signaling and loss of hypocretin neurons are causative for narcolepsy-cataplexy.
Aude Deloumeau +8 more
doaj +1 more source