Results 1 to 10 of about 314,078 (352)
Nature Reviews Disease Primers, 2015 Systemic sclerosis is a complex autoimmune disease characterized by a chronic and frequently progressive course and by extensive patient-to-patient variability. Like other autoimmune diseases, systemic sclerosis occurs more frequently in women, with a peak of onset in the fifth decade of life.
Yannick, Allanore +6 more
exaly +6 more sources
The Lancet, 2023 Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue disease. Once considered an untreatable and unpredictable condition, research advancements have improved our understanding of its disease pathogenesis and clinical phenotypes and expanded our treatment armamentarium.
Volkmann, Elizabeth R +2 more
openaire +6 more sources
European Medical Journal Rheumatology, 2020 Systemic sclerosis (SSc) is a complex autoimmune rheumatic disease that is characterised by widespread skin and internal organ fibrosis, immune system dysregulation, and vasculopathy.
Michael Hughes +3 more
doaj +2 more sources
Indian Journal of Dental Research, 2007 Systemic sclerosis (scleroderma) is a rare generalized disorder of connective tissue origin. This condition is predominantly a clinical diagnosis, based on the clinical signs and symptoms.
Ahathya R, Deepalakshmi D, Emmadi Pamela
doaj +3 more sources
Systemic sclerosis: Characterizing candidate retinal and choroidal imaging features using optical coherence tomography. [PDF]
PLoS ONEObjectivesSystemic sclerosis is a complex autoimmune disease characterized by vasculopathy and fibrosis, capable of affecting virtually any organ system, including the eyes.
Lilla Smeller +6 more
doaj +2 more sources
Diagnostics, 2023 Determination of salivary flow rate and oral status in patients with primary Sjögren’s Syndrome (pSS) and diffuse cutaneous systemic sclerosis (dcSSc) and comparison with control subjects.
Ana Glavina +6 more
doaj +1 more source
Is Th17-Targeted Therapy Effective in Systemic Lupus Erythematosus?
Current Issues in Molecular Biology, 2023 Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a broad spectrum of clinical manifestations. The proposed pathophysiological hypotheses of SLE are numerous, involving both innate and adaptive abnormal immune responses.
Marin Petrić, Mislav Radić
doaj +1 more source
The burden of systemic sclerosis in Switzerland – the Swiss systemic sclerosis EUSTAR cohort
Swiss Medical Weekly, 2021 OBJECTIVES Characteristics of Swiss patients with systemic sclerosis have not been described so far. The aim of the current study was to identify unmet needs in comparison with other European countries that could inform specific interventions
Jasmin Hernández +23 more
doaj +1 more source
Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension [PDF]
, 2014 Pulmonary arterial hypertension is a major complication of systemic sclerosis. Although oxidative stress, intima hyperplasia and a progressive vessel occlusion appear to be clearly involved, the fine molecular mechanisms underpinning the onset and ...
Boin, Francesco +8 more
core +8 more sources