Results 21 to 30 of about 163,479 (260)

Quantification of mitochondrial DNA damage and copy number in circulating blood of patients with systemic sclerosis by a qPCR-based assay, [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2020
Background: Although not fully understood, oxidative stress has been implicated in the pathogenesis of different autoimmune diseases such as systemic sclerosis.
Shafieh Movassaghi   +5 more
doaj   +1 more source

Single cell analysis in systemic sclerosis – A systematic review

open access: yesImmunological Medicine
In recent years, rapid advances in research methods have made single cell analysis possible. Systemic sclerosis (SSc), a disease characterized by the triad of immune abnormalities, fibrosis, and vasculopathy, has also been the subject of various analyses.
Takemichi Fukasawa   +6 more
doaj   +1 more source

Progressive systemic sclerosis in a child

open access: yesIndian Journal of Dermatology, 2013
Systemic sclerosis is a clinically heterogeneous systemic disease affecting the connective tissues of skin, walls of blood vessels and internal organs like lung, heart and kidneys. Systemic sclerosis is very unusual in pediatric population.
Arun K De   +3 more
doaj   +1 more source

Treatment of Systemic Sclerosis [PDF]

open access: yesRheumatic Disease Clinics of North America, 1989
Proper classification of patients into diffuse cutaneous and limited cutaneous subsets and the anticipation of complications are the keys to the management of individuals with systemic sclerosis (scleroderma). Patients with early diffuse disease and rapidly progressive skin thickening are at highest risk to develop serious internal organ involvement ...
openaire   +5 more sources

SYSTEMIC SCLEROSIS AND OSTEOPOROSIS

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
Systemic sclerosis is an autoimmune inflammatory disease of connective tissue with multi-syndrome clinical manifestations. Skeletal damage is considered to be one of significant contributors to the quality of life of these patients.
R. T. Alekperov, N. V. Toroptsova
doaj   +1 more source

Osteopetrosis in a Patient of Systemic Sclerosis Sine Scleroderma: A Rare Association

open access: yesIndian Journal of Radiology and Imaging, 2021
Systemic sclerosis is a connective tissue disorder of unknown etiology. Although it is a multisystemic disorder, skin thickening is considered as a hallmark of the disease.
Saroj K. Pati   +4 more
doaj   +1 more source

Pseudoainhum in Systemic Sclerosis [PDF]

open access: yesThe Journal of Rheumatology, 2016
Ainhum, also known as dactylolysis spontanea, is an idiopathic development of a fibrotic constricting band in a digit, most commonly affecting the fifth toe. Pseudoainhum refers to the same phenomenon when associated with other conditions, both hereditary and nonhereditary, such …
Mariana, Silva   +2 more
openaire   +2 more sources

Systemic sclerosis – diagnostic and therapeutic recommendations of the Polish Dermatological Society. Part 1: diagnosis and monitoring

open access: yesPrzegląd Dermatologiczny, 2017
Systemic sclerosis is an immune-mediated disease characterized by a chronic and progressive course. It often leads to multiorgan failure and patient disability, and contributes to significant reduction in the quality of life.
Dorota Krasowska   +10 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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