Gastrointestinal dysmotility in systemic sclerosis occurs as the end result of extensive fibrosis of the gastrointestinal tract. The entire length of the tract from the esophagus to the anorectum could be affected, exerting various gastrointestinal ...
Eka Benhardi Layadi +4 more
doaj +1 more source
Selected methods of rehabilitation in systemic sclerosis [PDF]
Systemic sclerosis is a chronic connective tissue disease characterized by microvascular abnormalities, immune disturbances and progressive fibrosis of the skin and internal organs.
Agnieszka Gerkowicz +4 more
core +1 more source
The prevalence of median neuropathy at wrist in systemic sclerosis patients at Srinagarind Hospital
Objectives: To determine the prevalence and factor related with median neuropathy at wrist (MNW) in systemic sclerosis patients. Study Design: Cross-sectional study. Setting: Srinagarind Hospital, Khon Kaen, Thailand.
Thanaporn Nimitbancha +3 more
doaj +1 more source
Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group [PDF]
INTRODUCTION: Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known.
Smith, Vanessa +87 more
core +1 more source
IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics [PDF]
Systemic sclerosis is an autoimmune connective tissue disease in which T cells play a prominent role. We and others have previously demonstrated a role for T cell-derived IL-13 in mediating the induction of collagen in dermal fibroblasts and that ...
van Laar, Jacob +12 more
core +1 more source
Depression is a common neuropsychiatric condition associated with systemic sclerosis. The association of depression and systemic sclerosis is the result of multiple mechanisms such as autoimmune, significant morbidity due to multi-system involvement ...
Aditya Somani +2 more
doaj +1 more source
Case report of systemic sclerosis: Uncommon manifestation of nephrotic syndrome post-renal crisis
Kidney involvement in systemic sclerosis occurs in about 20% of cases, with scleroderma renal crisis as a significant complication. However, cases of glomerular disease with massive proteinuria are rare.
Ai Fujii +10 more
doaj +1 more source
Systemic sclerosis and the gastrointestinal tract [PDF]
Systemic sclerosis (SSc) is an autoimmunological disease of unknown origin with complex pathogenesis and multiple organ involvement. It is characterised by vascular and immunological abnormalities leading to fibrosis of the skin and internal organs.
Irena Walecka
core +1 more source
Quantification of mitochondrial DNA damage and copy number in circulating blood of patients with systemic sclerosis by a qPCR-based assay, [PDF]
Background: Although not fully understood, oxidative stress has been implicated in the pathogenesis of different autoimmune diseases such as systemic sclerosis.
Shafieh Movassaghi +5 more
doaj +1 more source
Single cell analysis in systemic sclerosis – A systematic review
In recent years, rapid advances in research methods have made single cell analysis possible. Systemic sclerosis (SSc), a disease characterized by the triad of immune abnormalities, fibrosis, and vasculopathy, has also been the subject of various analyses.
Takemichi Fukasawa +6 more
doaj +1 more source

