Gastrointestinal dysmotility in systemic sclerosis occurs as the end result of extensive fibrosis of the gastrointestinal tract. The entire length of the tract from the esophagus to the anorectum could be affected, exerting various gastrointestinal ...
Eka Benhardi Layadi +4 more
doaj +1 more source
Lung ultrasound in systemic sclerosis: correlation with high-resolution computed tomography, pulmonary function tests and clinical variables of disease [PDF]
Interstitial lung disease (ILD) is a hallmark of systemic sclerosis (SSc). Although high-resolution computed tomography (HRCT) is the gold standard to diagnose ILD, recently lung ultrasound (LUS) has emerged in SSc patients as a new promising technique ...
Amoroso, Antonio +8 more
core +1 more source
Spinal anesthesia for cesarean section in a patient with systemic sclerosis associated interstitial lung disease: a case report [PDF]
Systemic sclerosis or scleroderma is a rare autoimmune disorder characterized by excessive fibrosis and, vasculopathy, with multiorgan involvement. Anesthetic considerations in patients with systemic sclerosis must take into account the degree of organ ...
Guie Yong Lee, Sooyoung Cho
doaj +1 more source
In systemic sclerosis skin perfusion of hands is reduced and may predict the occurrence of new digital ulcers [PDF]
Systemic sclerosis (SSc) patients are at high risk for the development of ischemic digital ulcers (DUs). The aim of this study was to assess in SSc patients a correlation between skin perfusion evaluated by LDPI and DUs and to evaluate the prognostic ...
Barbano, Biagio +6 more
core +1 more source
The prevalence of median neuropathy at wrist in systemic sclerosis patients at Srinagarind Hospital
Objectives: To determine the prevalence and factor related with median neuropathy at wrist (MNW) in systemic sclerosis patients. Study Design: Cross-sectional study. Setting: Srinagarind Hospital, Khon Kaen, Thailand.
Thanaporn Nimitbancha +3 more
doaj +1 more source
Systemic sclerosis: current views of its pathogenesis. [PDF]
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the microvasculature, and numerous cellular and humoral immune abnormalities ...
Derk, Chris T., Jimenez, Sergio A.
core +2 more sources
Case report of systemic sclerosis: Uncommon manifestation of nephrotic syndrome post-renal crisis
Kidney involvement in systemic sclerosis occurs in about 20% of cases, with scleroderma renal crisis as a significant complication. However, cases of glomerular disease with massive proteinuria are rare.
Ai Fujii +10 more
doaj +1 more source
Oxidative stress in the pathogenesis of systemic scleroderma: An overview [PDF]
Systemic sclerosis (SSc) is a rare disorder of the connective tissue characterized by fibrosis of the skin, skeletal muscles and visceral organs. Additional manifestations include activation of the immune system and vascular injury. SSc causes disability
Gambardella, Lucrezia +5 more
core +1 more source
Definition of Naturally Processed Peptides Reveals Convergent Presentation of Autoantigenic Topoisomerase I Epitopes in Scleroderma. [PDF]
ObjectiveAutoimmune responses to DNA topoisomerase I (topo I) are found in a subset of scleroderma patients who are at high risk for interstitial lung disease (ILD) and mortality.
Boin, Francesco +9 more
core +1 more source
Depression is a common neuropsychiatric condition associated with systemic sclerosis. The association of depression and systemic sclerosis is the result of multiple mechanisms such as autoimmune, significant morbidity due to multi-system involvement ...
Aditya Somani +2 more
doaj +1 more source

