Results 31 to 40 of about 2,931,663 (352)
European Medical Journal Rheumatology, 2020 Systemic sclerosis (SSc) is a complex autoimmune rheumatic disease that is characterised by widespread skin and internal organ fibrosis, immune system dysregulation, and vasculopathy.
Michael Hughes +3 more
doaj +1 more source
Arthritis Research & Therapy, 2021 Highlights • Male sex, cardiac involvement, DLCO 5 mg/l are strong predictors of mortality in systemic sclerosis. • This study shows the survival of subtypes and in particular sine scleroderma. • Sine scleroderma subtype has better survival than diffuse
Sébastien De Almeida Chaves +13 more
doaj +1 more source
The Lancet Rheumatology, 2021 BACKGROUND Systemic sclerosis is a connective tissue disease characterised by multiorgan fibrosis with an autoimmune background and poor prognosis. Although a few drugs have shown some efficacy in treating the disease, there remains a great unmet medical
S. Ebata +14 more
semanticscholar +1 more source
Systemic sclerosis and risk of bronchiectasis: a nationwide longitudinal cohort study
Arthritis Research & Therapy, 2023 Background The association between systemic sclerosis and the development of bronchiectasis is unclear. This study aimed to compare the risk of bronchiectasis between individuals with systemic sclerosis and those without using a nationwide longitudinal ...
Bumhee Yang +11 more
doaj +1 more source
Tocilizumab Prevents Progression of Early Systemic Sclerosis Associated Interstitial Lung Disease
Arthritis & Rheumatology, 2021 Tocilizumab (TCZ) has demonstrated lung function preservation in 2 randomized controlled trials in early systemic sclerosis (SSc). This effect has yet to be characterized in terms of radiographically evident quantitative lung involvement.
D. Roofeh +7 more
semanticscholar +1 more source
Exercise for people with systemic sclerosis or systemic lupus erythematosus [PDF]
, 2023 Aims: The aim of this research was to identify the effectiveness and experience of exercise in adults with systemic lupus erythematosus (SLE) and systemic sclerosis (SSc).
Frade, Stephanie
core +1 more source
Living with Systemic Sclerosis: A Patient and Physician Perspective
Rheumatology and Therapy, 2023 The fears associated with being diagnosed with a disease unfamiliar to many, systemic sclerosis, is described by a patient living with systemic sclerosis.
Arissa Young +2 more
doaj +1 more source
Current Advances in the Treatment of Systemic Sclerosis
Current opinion in pharmacology (Print), 2022 Systemic sclerosis (SSc) is a rare, systemic autoimmune disease of unknown etiology. Among the systemic rheumatic diseases, SSc carries the highest mortality, in part due to the historical lack of disease modifying therapies.
H. Bukiri, E. Volkmann
semanticscholar +1 more source
Multiplex cytokine analysis of dermal interstitial blister fluid defines local disease mechanisms in systemic sclerosis. [PDF]
, 2015 Clinical diversity in systemic sclerosis (SSc) reflects multifaceted pathogenesis and the effect of key growth factors or cytokines operating within a disease-specific microenvironment.
Christopher P Denton +21 more
core +1 more source
Current Concepts on the Pathogenesis of Systemic Sclerosis
Clinical reviews in allergy and immunology, 2021 From the clinical standpoint, systemic sclerosis (SSc) is characterized by skin and internal organ fibrosis, diffuse fibroproliferative vascular modifications, and autoimmunity. Clinical presentation and course are highly heterogenous and life expectancy
M. Truchetet +2 more
semanticscholar +1 more source