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The impact of ageing mechanisms on musculoskeletal system diseases in the elderly
Frontiers in ImmunologyAgeing is an inevitable process that affects various tissues and organs of the human body, leading to a series of physiological and pathological changes.Yijin Cai, Zhongyu Han, Hong Cheng, Hongpeng Li, Ke Wang, Jia Chen, Zhi-Xiang Liu, Yulong Xie, Yumeng Lin, Shuwei Zhou, Siyu Wang, Xiao Zhou, Song Jin +12 moredoaj +3 more sourcesEndothelial Progenitor Cells: Relevant Players in the Vasculopathy and Lung Fibrosis Associated with the Presence of Interstitial Lung Disease in Systemic Sclerosis Patients
Biomedicines, 2021 Endothelial progenitor cells (EPC), which are key effectors in the physiologic vascular network, have been described as relevant players in autoimmune diseases.Verónica Pulito-Cueto, Sara Remuzgo-Martínez, Fernanda Genre, Belén Atienza-Mateo, Víctor M. Mora-Cuesta, David Iturbe-Fernández, Leticia Lera-Gómez, Raquel Pérez-Fernández, Diana Prieto-Peña, Virginia Portilla, Ricardo Blanco, Alfonso Corrales, Oreste Gualillo, José M. Cifrián, Raquel López-Mejías, Miguel A. González-Gay +15 moredoaj +1 more sourceAngiogenic T Cells: Potential Biomarkers for the Early Diagnosis of Interstitial Lung Disease in Autoimmune Diseases?
Biomedicines, 2022 (1) Background: We explored, for the first time, the contribution of angiogenic T cells (TAng) in interstitial lung disease associated to autoimmune disease (AD-ILD+) as potential biomarkers of the disease, evaluating their role in the underlying ...Verónica Pulito-Cueto, Sara Remuzgo-Martínez, Fernanda Genre, Belén Atienza-Mateo, Víctor M. Mora-Cuesta, David Iturbe-Fernández, Leticia Lera-Gómez, Javier Rodriguez-Carrio, Diana Prieto-Peña, Virginia Portilla, Ricardo Blanco, Alfonso Corrales, Oreste Gualillo, José M. Cifrián, Raquel López-Mejías, Miguel A. González-Gay +15 moredoaj +1 more sourceRole of VEGF Polymorphisms in the Susceptibility and Severity of Interstitial Lung Disease
Biomedicines, 2021 The search for biomarkers that can help to establish an early diagnosis and prognosis of interstitial lung disease (ILD) is of potential interest. VEGF polymorphisms have been implicated in the development of several lung disorders.Sara Remuzgo-Martínez, Fernanda Genre, Verónica Pulito-Cueto, Belén Atienza-Mateo, Víctor Manuel Mora Cuesta, David Iturbe Fernández, Sonia María Fernández Rozas, Leticia Lera-Gómez, Pilar Alonso Lecue, María Piedad Ussetti, Rosalía Laporta, Cristina Berastegui, Amparo Solé, Virginia Pérez, Alicia De Pablo Gafas, Oreste Gualillo, José Manuel Cifrián, Raquel López-Mejías, Miguel Ángel González-Gay +18 moredoaj +1 more sourceElevated VCAM-1, MCP-1 and ADMA serum levels related to pulmonary fibrosis of interstitial lung disease associated with rheumatoid arthritis
Frontiers in Molecular Biosciences, 2022 Introduction: Early diagnosis of interstitial lung disease (ILD) associated with rheumatoid arthritis (RA) constitutes a challenge for the clinicians. Pulmonary vasculopathy is relevant in the development of interstitial lung disease.Verónica Pulito-Cueto, Sara Remuzgo-Martínez, Fernanda Genre, Belén Atienza-Mateo, Belén Atienza-Mateo, Víctor M. Mora-Cuesta, Víctor M. Mora-Cuesta, David Iturbe-Fernández, David Iturbe-Fernández, Leticia Lera-Gómez, María Sebastián Mora-Gil, Diana Prieto-Peña, Diana Prieto-Peña, Virginia Portilla, Virginia Portilla, Ricardo Blanco, Ricardo Blanco, Alfonso Corrales, Alfonso Corrales, J. Gonzalo Ocejo-Vinyals, Oreste Gualillo, Iván Ferraz-Amaro, José M. Cifrián, José M. Cifrián, José M. Cifrián, Raquel López-Mejías, Miguel A. González-Gay, Miguel A. González-Gay +27 moredoaj +1 more sourceRole of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome
Scientific Reports, 2021 Mucin 1/Krebs von den Lungen-6 (KL-6) is proposed as a serum biomarker of several interstitial lung diseases (ILDs), including connective tissue disorders associated with ILD. However, it has not been studied in a large cohort of Caucasian antisynthetase Sara Remuzgo-Martínez, Belén Atienza-Mateo, J. Gonzalo Ocejo-Vinyals, Fernanda Genre, Verónica Pulito-Cueto, Víctor M. Mora-Cuesta, David Iturbe-Fernández, Leticia Lera-Gómez, Raquel Pérez-Fernández, Diana Prieto-Peña, Juan Irure, Fredeswinda Romero-Bueno, Olga Sanchez-Pernaute, Rodrigo Alonso-Moralejo, Laura Nuño, Gema Bonilla, Esther F. Vicente-Rabaneda, Ignacio Grafia, Sergio Prieto-González, Javier Narvaez, Ernesto Trallero-Araguas, Albert Selva-O’Callaghan, Spanish Biomarkers of Antisynthetase Syndrome Consortium, Spanish Biomarkers of Interstitial Lung Disease Consortium, Oreste Gualillo, Lorenzo Cavagna, José M. Cifrián, Elisabetta A. Renzoni, Santos Castañeda, Raquel López-Mejías, Miguel A. González-Gay +30 moredoaj +1 more sourceVaspin in atherosclerotic disease and cardiovascular risk in axial spondyloarthritis: a genetic and serological study
Arthritis Research & Therapy, 2021 Background Vaspin is a novel anti-inflammatory adipokine associated with cardiovascular (CV) disease and inflammation in chronic inflammatory conditions different from axial spondyloarthritis (axSpA). Given the high incidence of CV disease (mainly due to Javier Rueda-Gotor, Raquel López-Mejías, Sara Remuzgo-Martínez, Verónica Pulito-Cueto, Alfonso Corrales, Leticia Lera-Gómez, Virginia Portilla, Íñigo González-Mazón, Ricardo Blanco, Rosa Expósito, Cristina Mata, Javier Llorca, Vanesa Hernández-Hernández, Carlos Rodríguez-Lozano, Nuria Barbarroja, Rafaela Ortega Castro, Esther Vicente, Cristina Fernández-Carballido, María Paz Martínez-Vidal, David Castro-Corredor, Joaquín Anino-Fernández, Diana Peiteado, Chamaida Plasencia-Rodríguez, Eva Galíndez-Agirregoikoa, María Luz García-Vivar, Oreste Gualillo, Juan Carlos Quevedo-Abeledo, Santos Castañeda, Iván Ferraz-Amaro, Miguel Á. González-Gay, Fernanda Genre +30 moredoaj +1 more sourceIrisin as a Novel Biomarker of Subclinical Atherosclerosis, Cardiovascular Risk and Severe Disease in Axial Spondyloarthritis
Frontiers in Immunology, 2022 IntroductionPatients with axial spondyloarthritis (axSpA) have a high disease burden mainly due to the rheumatic disease itself, and also exhibit accelerated atherosclerosis, that leads to a higher incidence of cardiovascular (CV) disease.Sara Remuzgo-Martínez, Javier Rueda-Gotor, Verónica Pulito-Cueto, Raquel López-Mejías, Alfonso Corrales, Leticia Lera-Gómez, Raquel Pérez-Fernández, Virginia Portilla, Íñigo González-Mazón, Ricardo Blanco, Rosa Expósito, Cristina Mata, Javier Llorca, Javier Llorca, Vanesa Hernández-Hernández, Carlos Rodríguez-Lozano, Nuria Barbarroja, Rafaela Ortega-Castro, Esther Vicente, Cristina Fernández-Carballido, María Paz Martínez-Vidal, David Castro-Corredor, Joaquín Anino-Fernández, Diana Peiteado, Chamaida Plasencia-Rodríguez, Eva Galíndez-Agirregoikoa, María Luz García-Vivar, Nuria Vegas-Revenga, Irati Urionaguena, Oreste Gualillo, Juan Carlos Quevedo-Abeledo, Santos Castañeda, Iván Ferraz-Amaro, Miguel Á. González-Gay, Miguel Á. González-Gay, Miguel Á. González-Gay, Miguel Á. González-Gay, Fernanda Genre +37 moredoaj +1 more sourceRole of the IL33 and IL1RL1 pathway in the pathogenesis of Immunoglobulin A vasculitis
Scientific Reports, 2021 Cytokines signalling pathway genes are crucial factors of the genetic network underlying the pathogenesis of Immunoglobulin-A vasculitis (IgAV), an inflammatory vascular condition.Diana Prieto-Peña, Sara Remuzgo-Martínez, Fernanda Genre, Verónica Pulito-Cueto, Belén Atienza-Mateo, Javier Llorca, Belén Sevilla-Pérez, Norberto Ortego-Centeno, Ana Marquez, Leticia Lera-Gómez, María Teresa Leonardo, Ana Peñalba, Javier Narváez, Luis Martín-Penagos, Emilio Rodrigo, José A. Miranda-Filloy, Luis Caminal-Montero, Paz Collado, Javier Sánchez Pérez, Diego de Argila, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Oreste Gualillo, Javier Martín, Santos Castañeda, Ricardo Blanco, Miguel A. González-Gay, Raquel López-Mejías +29 moredoaj +1 more sourcePredicting survival of patients with bone metastasis of unknown origin
Frontiers in Endocrinology, 2023 PurposeBone metastasis of unknown origin is a rare and challenging situation, which is infrequently reported. Therefore, the current study was performed to analyze the clinicopathologic features and risk factors of survival among patients with bone ...Ying Ren, Ying Ren, Ying Ren, Ying Ren, Ying Ren, Ying Ren, Shengjun Qian, Shengjun Qian, Shengjun Qian, Shengjun Qian, Shengjun Qian, Guoping Xu, Guoping Xu, Guoping Xu, Guoping Xu, Guoping Xu, Guoping Xu, Zhenhai Cai, Ning Zhang, Ning Zhang, Ning Zhang, Ning Zhang, Ning Zhang, Zhan Wang, Zhan Wang, Zhan Wang, Zhan Wang, Zhan Wang +27 moredoaj +1 more source