Results 41 to 50 of about 313,619 (310)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

INFLUENCE OF WORKING CONDITIONS ON THE OCCURRENCE AND PREVALENCE OF DISEASES MUSCULOSKELETAL SYSTEM OF THE WORKERS OF LLC "TOLYATTI TRANSFORMER"

Юг России: экология, развитие, 2014
The influence of working conditions upon the occurrence and (or) prevalence of the musculoskeletal system diseases according to the results of the periodical medical examinations of Co. ltd. “TOGLIATTY TRANSFORMATOR” workers is analyzed.
E. V. Semina, O. A. Rozenzvet
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Spreading of diseases through comorbidity networks across life and gender [PDF]

, 2014
The state of health of patients is typically not characterized by a single disease alone but by multiple (comorbid) medical conditions. These comorbidities may depend strongly on age and gender.
Chmiel, Anna, Klimek, Peter, Thurner, Stefan   +2 more
core   +2 more sources

Performance Characteristics of Anti–Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick, Marcela A. Ferrada, Alice Fike, Kaitlin A. Quinn, Benjamin A. Turturice, Casey Stein, Peter C Grayson   +6 more
wiley   +1 more source

The primary role of radiological imaging in the diagnosis of rare musculoskeletal diseases. Emphasis on ultrasound

Journal of Ultrasonography, 2019
Objective: In July 2017 a multidisciplinary clinical Center specialized in rare diseases was activated. A rare disease can involve the musculoskeletal system. A multimodality musculoskeletal imaging approach allows for a rapid diagnosis.
Rossi Federica, Martinoli Carlo, Murialdo Giovanni, Schenone Angelo, Grandis Marina, Ferone Diego, Tagliafico Alberto Stefano   +6 more
doaj   +1 more source

Obesity in rheumatological practice

Rheumatology, 2023
Obesity is a chronic disease that leads to the development of secondary metabolic disturbances and diseases and strongly contributes to increased morbidity and mortality.
Jarosław Kozakowski, Piotr Dudek, Wojciech Zgliczyński   +2 more
doaj   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Correction of disordered equilibrium function in students through exercise therapy

Бюллетень сибирской медицины, 2009
The method of stabilography was used to study the equilibrium function in students with vascular heart diseases and diseases of musculoskeletal system going in for exercise therapy (ET). The organization of physical training with the use exercise therapy
K. V. Davletiyarova, V. L. Soltanova, L. V. Kapilevich, V. I. Andreyev   +3 more
doaj   +1 more source

Out-of-hours primary care services: Demands and patient referral patterns in a Veneto region (Italy) Local Health Authority [PDF]

, 2015
open7PURPOSE: The aim of this study was to describe the characteristics of patients admitted to an out-of-hours (OOH) service and to analyze the related outputs.
Baldo, Vincenzo, Buja, Alessandra, Carraro, Daniela, Damiani, Gianfranco (ORCID:0000-0003-3028-6188), Rigon, Stefano, Sandona', Paolo, Toffanin, Roberto   +6 more
core   +1 more source