Irisin in degenerative musculoskeletal diseases: Functions in system and potential in therapy
Pharmacological ResearchDegenerative musculoskeletal diseases are a class of diseases related to the gradual structural and functional deterioration of muscles, joints, and bones, including osteoarthritis (OA), osteoporosis (OP), sarcopenia (SP), and intervertebral disc ...
Yu-tong Wang +8 more
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Omentin: a biomarker of cardiovascular risk in individuals with axial spondyloarthritis
Scientific Reports, 2020 Cardiovascular (CV) disease is the main cause of mortality in axial spondyloarthritis (axSpA). CV risk is enhanced by dysregulation of adipokines. Low omentin levels were associated with metabolic dysfunction and CV disease in conditions different from ...
Fernanda Genre +24 more
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BAFF, APRIL and BAFFR on the pathogenesis of Immunoglobulin-A vasculitis
Scientific Reports, 2021 BAFF, APRIL and BAFF-R are key proteins involved in the development of B-lymphocytes and autoimmunity. Additionally, BAFF, APRIL and BAFFR polymorphisms were associated with immune-mediated conditions, being BAFF GCTGT>A a shared insertion-deletion ...
Diana Prieto-Peña +28 more
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Bioengineering, 2023 Due to the high prevalence and rates of disability associated with musculoskeletal system diseases, more thorough research into diagnosis, pathogenesis, and treatments is required.
Tianze Sun +7 more
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Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]
, 2012 Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
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What is the association between sickness absence, mortality and morbidity? [PDF]
, 2005 This paper examines the area-level relationships in England and Wales between sickness absence (‘incapacity benefit’), mortality and morbidity. It uses a random sample of incapacity benefit claims, and population counts of mortality and Census morbidity ...
C. Bambra +11 more
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Health-related quality of life as measured with EQ-5D among populations with and without specific chronic conditions: A population-based survey in Shaanxi province, China [PDF]
, 2013 © 2013 Tan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
A Alwan +36 more
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Optimal treatment strategies for musculoskeletal diseases [PDF]
, 2013 This paper presents a model which aims to find an optimal treatment time for patients with musculoskeletal diseases. The stochastic dynamic programming model presented is based on minimizing expected costs given a stochastic processes for cure with ...
Haugen, Kjetil K.
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Prevalence and time course of post-stroke pain: A multicenter prospective hospital-based study [PDF]
, 2015 OBJECTIVE: Pain prevalence data for patients at various stages after stroke. DESIGN: Repeated cross-sectional, observational epidemiological study. SETTING: Hospital-based multicenter study.
Barbanti, Piero +17 more
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Lived experiences of informal caregivers of people with chronic musculoskeletal pain: a systematic review and meta-ethnography [PDF]
, 2021 BACKGROUND: People with chronic pain often seek support from friends and family for everyday tasks. These individuals are termed informal caregivers. There remains uncertainty regarding the lived experiences of these people who care for individuals with ...
Bowlby J. +6 more
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