Results 1 to 10 of about 63,061 (167)

IL-1β/IL-1Ra ratio dysregulation in islet autoantibody–positive adult-onset diabetes [PDF]

open access: yesFrontiers in Immunology
BackgroundThe IL-1 pathway plays a central role in β-cell dysfunction; however, the relationship between IL-1β/IL-1Ra imbalance and islet autoimmunity in newly diagnosed adult-onset diabetes remains insufficiently defined.
Bibigul Tleumagambetova   +3 more
doaj   +2 more sources

Comprehensive autoantibody profiling in systemic autoimmunity by a highly-sensitive multiplex protein array

open access: yesFrontiers in Immunology, 2023
Comprehensive autoantibody evaluation is essential for the management of autoimmune disorders. However, conventional methods suffer from poor sensitivity, low throughput, or limited availability.
Chihiro Ono   +2 more
exaly   +3 more sources

Anti-Myxovirus Resistance Protein-1 Immunoglobulin A Autoantibody in Idiopathic Pulmonary Fibrosis

open access: yesCanadian Respiratory Journal, 2022
Background. We have previously analysed serum autoantibody levels in patients with idiopathic pulmonary fibrosis (IPF), idiopathic nonspecific interstitial pneumonia (iNSIP), and healthy controls and identified the autoantibody against anti-myxovirus ...
Toru Arai   +7 more
doaj   +1 more source

Effectiveness of pirfenidone in idiopathic pulmonary fibrosis according to the autoantibody status: a retrospective cohort study

open access: yesBMC Pulmonary Medicine, 2021
Background Pirfenidone is an anti-fibrotic agent shown to slow the progression of idiopathic pulmonary fibrosis (IPF). However, its effectiveness in association with serological autoimmune features in IPF remains unclear.
Myung Jin Song   +7 more
doaj   +1 more source

First-emerging islet autoantibody and glucose metabolism: search for type 1 diabetes subtypes

open access: yesEndocrine Connections, 2022
Objective: Subtypes in type 1 diabetes pathogenesis have been implicated based on the first-appearing autoantibody (primary autoantibody). We set out to describe the glucose metabolism in preclinical diabetes in relation to the primary autoantibody in ...
Olli Helminen   +6 more
doaj   +1 more source

Lymphocytotoxic Autoantibodies [PDF]

open access: yes, 2007
Anti-lymphocytic antibodies (anti-LCA) are detected in patients with systemic lupus erythematosus (SLE) with a prevalence ranging from 60–90%. LCA detection is associated with nephritis and neurologic disorders in these patients, and high rates of LCA occur during phases of active SLE.
Renaudineau, Yves   +2 more
openaire   +2 more sources

Correlates of survival after autoantibody reduction therapy for acute IPF exacerbations.

open access: yesPLoS ONE, 2021
BackgroundNo medical treatment has proven efficacy for acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF), and this syndrome has a very high mortality.
Tejaswini Kulkarni   +10 more
doaj   +1 more source

Use of two methods to elute anti-IgG and anti-(IgG + C3d) type autoantibody from sensitized erythrocytes

open access: yesGlobal Journal of Transfusion Medicine, 2018
Background: Autoimmune hemolytic anemia (AIHA) is an immunological disease caused by autoantibodies. Warm autoantibody mainly includes anti-IgG and anti-(IgG+C3d) type, which can cause direct antiglobulin test (DAT) positive.
He Ziyi, Hu Yingming, Cui Siping
doaj   +1 more source

Autoantibody of NRIP, a novel AChR‐interacting protein, plays a detrimental role in myasthenia gravis

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2021
Background Nuclear receptor interaction protein (NRIP) co‐localizes with acetylcholine receptor (AChR) at the neuromuscular junction (NMJ), and NRIP deficiency causes aberrant NMJ architecture.
Li‐Kai Tsai   +10 more
doaj   +1 more source

Comparison of clinical and laboratory characteristics in children with type 1 diabetes according to pancreatic autoantibodies [PDF]

open access: yesKorean Journal of Pediatrics, 2010
Purpose:The purpose of this study was to determine whether there is any difference in the clinical and laboratory characteristics of patients with autoantibody-positive and patients with autoantibody-negative type 1 diabetes at initial presentation ...
Ji Hae Choi   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy