Results 1 to 10 of about 33,778 (258)
Autoantibodies in chronic non-infectious respiratory diseases: a scoping review [PDF]
Frontiers in ImmunologyWe performed a scoping review assessing autoantibodies across chronic non-infectious respiratory diseases including idiopathic pulmonary fibrosis, idiopathic interstitial pneumonias, chronic obstructive pulmonary disease, cystic fibrosis, asthma ...
Ke Li Chow +11 more
doaj +2 more sources
Molecular Portrait of Autoantigens in Type 1 Diabetes [PDF]
BiomoleculesThis review focuses on the molecular pathogenesis of Type 1 diabetes (T1D), specifically on the key autoantigens targeted by the autoimmune response and the clinical implications of their epitope specificity.
Ilya Kandinov +4 more
doaj +2 more sources
Frontiers in Immunology, 2019 Infections are considered important environmental triggers of autoimmunity and can contribute to autoimmune disease onset and severity. Nucleic acids and the complexes that they form with proteins—including chromatin and ribonucleoproteins—are the main ...
Roberto Caricchio +2 more
exaly +3 more sources
Diagnostics, 2023 Background: COVID-19 is a heterogenous disease resulting in long-term sequela in predisposed individuals. It is not uncommon that recovering patients endure non-respiratory ill-defined manifestations, including anosmia, and neurological and cognitive ...
Aristo Vojdani, Israel Zyskind
exaly +3 more sources
Frontiers in Endocrinology, 2022 Type 1 Diabetes (T1D) is an autoimmune disease that results from the destruction of pancreatic islet β-cells by auto-reactive T cells. The clinical management of T1D faces the lack of fully predictive biomarkers in its preclinical stage and of antigen ...
Pamela Houeiss +5 more
doaj +1 more source
Fcγ receptor activation mediates vascular inflammation and abdominal aortic aneurysm development
Clinical and Translational Medicine, 2021 Background Abdominal aortic aneurysm (AAA), a degenerative vascular pathology characterized by permanent dilation of the aorta, is considered a chronic inflammatory disease involving innate/adaptive immunity.
Laura Lopez‐Sanz +9 more
doaj +1 more source
Aminoacyl-tRNA Synthetases: On Anti-Synthetase Syndrome and Beyond
Frontiers in Immunology, 2022 Anti-synthetase syndrome (ASSD) is an autoimmune disease characterized by the presence of autoantibodies targeting one of several aminoacyl t-RNA synthetases (aaRSs) along with clinical features including interstitial lung disease, myositis, Raynaud’s ...
Angeles S. Galindo-Feria +6 more
doaj +1 more source
Frontiers in Immunology, 2022 COVID-19 is accompanied by a myriad of both transient and long-lasting autoimmune responses. Dermatan sulfate (DS), a glycosaminoglycan crucial for wound healing, has unique affinity for autoantigens (autoAgs) from apoptotic cells.
Julia Y. Wang +5 more
doaj +1 more source
B‐cell receptors of EBV‐negative Burkitt lymphoma bind modified isoforms of autoantigens
eJHaem, 2022 Burkitt lymphoma (BL) represents the most aggressive B‐cell‐lymphoma. Beside the hallmark of IG‐MYC‐translocation, surface B‐cell receptor (BCR) is expressed, and mutations in the BCR pathway are frequent.
Theresa Bock +24 more
doaj +1 more source
Frontiers in Immunology, 2020 The current paradigm of onset and progression of periodontitis includes oral dysbiosis directed by inflammophilic bacteria, leading to altered resolution of inflammation and lack of regulation of the inflammatory responses.
Lina J. Suárez +3 more
doaj +1 more source