Results 11 to 20 of about 33,778 (258)
Immunogenicity of autoantigens [PDF]
BMC Genomics, 2011 Background Autoantibodies against self-antigens have been associated not only with autoimmune diseases, but also with cancer and are even found in healthy individuals.
Keller Andreas +7 more
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Post-translational modifications, subcellular relocation and release in apoptotic microparticles: apoptosis turns nuclear proteins into autoantigens. [PDF]
Folia Histochemica et Cytobiologica, 2010 Autoantibodies against particular nuclear components, such as chromatin and snRNPs, are a characteristic feature of the autoimmune disease systemic lupus erythematosus.
Sylviane Muller, JĂźrgen Dieker
doaj +4 more sources
Studies on autoantigens in rheumatoid arthritis [PDF]
, 2003 This thesis describes the use of phage display for the isolation of autoantigens in rheumatoid arthritis. The potential of the technology is demonstrated by the isolation of an autoantigen, eukaryotic translation elongation factor 1a1 (eEF 1 (x 1) from a
Mewar, Devesh
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Enhanced Expression of Autoantigens During SARS-CoV-2 Viral Infection [PDF]
, 2021 Immune homeostasis is disturbed during severe viral infections, which can lead to loss of tolerance to self-peptides and result in short- or long-term autoimmunity.
Saheb Sharif-Askari, Fatemeh +13 more
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Anti-Idiotypic mRNA Vaccine to Treat Autoimmune Disorders
Vaccines, 2023 The 80+ existing autoimmune disorders (ADs) affect billions with little prevention or treatment options, except for temporary symptomatic management, leading to enormous human suffering and a monumental financial burden. The autoantibodies formed in most
Sarfaraz K. Niazi
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Life, 2023 Wet age-related macular degeneration (wAMD) is a chronic inflammation-associated neurodegenerative disease affecting the posterior part of the eye in the aging population.
Sreeraj Kuruppilakath Manikandan +6 more
doaj +1 more source
The Role of Heat Shock Proteins in Type 1 Diabetes
Frontiers in Immunology, 2021 Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease characterized by recognition of pancreatic β-cell proteins as self-antigens, called autoantigens (AAgs), followed by loss of pancreatic β-cells.
Abu Saleh Md Moin +4 more
doaj +1 more source
Interferon and autoantigens: intersection in autoimmunity [PDF]
, 2023 Interferon (IFN) is a key component of the innate immune response. For reasons that remain incompletely understood, the IFN system is upregulated in several rheumatic diseases, particularly those that feature autoantibody production, such as SLE, Sjögren’
Brendan Antiochos, Livia Casciola-Rosen
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Neutrophils: An Important Player in Systemic Lupus Erythematosus [PDF]
Journal of Clinical and Diagnostic ResearchThe immune system contains several different cells that act as the first line of defence, reacting to a broad range of intruders as quickly as possible; an example of such cells is neutrophils. There has been increased focus on neutrophils due to the key
Nuha A Alkhattabi
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Retinal glycoprotein enrichment by concanavalin a enabled identification of novel membrane autoantigen synaptotagmin-1 in equine recurrent uveitis. [PDF]
, 2012 Complete knowledge of autoantigen spectra is crucial for understanding pathomechanisms of autoimmune diseases like equine recurrent uveitis (ERU), a spontaneous model for human autoimmune uveitis. While several ERU autoantigens were identified previously,
Cornelia A. Deeg +23 more
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