Results 1 to 10 of about 2,474,551 (357)

Predicting the functional effect of amino acid substitutions and indels.

open access: yesPLoS ONE, 2012
As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being developed to provide computational predictions on the functional effects of sequence variations and narrow down the search of ...
Yongwook Choi   +4 more
doaj   +2 more sources

SSE: a nucleotide and amino acid sequence analysis platform

open access: yesBMC Research Notes, 2012
Background There is an increasing need to develop bioinformatic tools to organise and analyse the rapidly growing amount of nucleotide and amino acid sequence data in organisms ranging from viruses to eukaryotes.
Simmonds Peter
doaj   +2 more sources

Organizing the bacterial annotation space with amino acid sequence embeddings [PDF]

open access: yesBMC Bioinformatics, 2022
Background Due to the ever-expanding gap between the number of proteins being discovered and their functional characterization, protein function inference remains a fundamental challenge in computational biology.
Susanna R. Grigson   +3 more
doaj   +2 more sources

THE AMINO ACID SEQUENCE OF HYPERTENSIN II [PDF]

open access: yesJournal of Experimental Medicine, 1956
The amino acid sequence of horse hypertensin II has been determined by the use of chymotrypsin, the fluorodinitrobenzene method, and stepwise phenylisothiocyanate degradation. The results indicate that the amino acids of hypertensin II are arranged in the following order: asp-arg-val-tyr-iso-hist-pro-phe.
Leonard T Skeggs   +2 more
exaly   +3 more sources

Protein Solubility Prediction Based on Sequence Feature Fusion [PDF]

open access: yesJisuanji kexue, 2022
Protein solubility plays an important role in the research of drug design.Traditional biological experiments of detecting protein solubility are time-consuming and laborious.Identifying protein solubility based on computational methods has become an ...
NIU Fu-sheng, GUO Yan-bu, LI Wei-hua, LIU Wen-yang
doaj   +1 more source

Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus [PDF]

open access: yesPeerJ, 2020
Macrobrachium carcinus (Linnaeus, 1758) is a species of freshwater shrimp widely distributed from Florida southwards to southern Brazil, including southeast of Mexico.
José M. Viader-Salvadó   +5 more
doaj   +2 more sources

Comparative Study on Feature Selection Methods for Protein [PDF]

open access: yesInternational Journal of Intelligent Computing and Information Sciences, 2022
The automated and high-throughput identification of protein function is one of the main issues in computational biology. Predicting the protein's structure is a crucial step in this procedure.
Walaa Gad   +2 more
doaj   +1 more source

Multiple re-reads of single proteins at single-amino-acid resolution using nanopores

open access: yesScience, 2021
Description Reading amino acids by nanopore Nanopore technology enables sensing of minute chemical changes at the single-molecule level by detecting differences in an ion current as molecules are drawn through a membrane-embedded pore. The sensitivity is
H. Brinkerhoff   +4 more
semanticscholar   +1 more source

Amino acid sequence of rabbit apolipoprotein E.

open access: yesJournal of Lipid Research, 1991
The complete amino acid sequence of rabbit apolipoprotein E (apoE) was determined by generating three sets of peptides using cyanogen bromide, endoproteinase AspN, and Staphylococcus aureus V8 protease to cleave the protein.
BR Lee   +6 more
doaj   +1 more source

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