Results 31 to 40 of about 2,474,551 (357)
GASP: gapped ancestral sequence prediction for proteins
, 2004 Background: the prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a simple procedure and relies on accurate alignments and phylogenies.
Denis C. Shields (18564) +7 more
core +1 more source
Journal of Infection in Developing Countries, 2011 Introduction: Hepatitis C virus (HCV), which is a major cause of liver diseases worldwide, undergoes genetic variation during the course of infection. The aim of this study was to examine sequence variations within the HVR1 region of HCV genotype 4 in ...
Ahmed Ali Al-Qahtani +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Predicting protein disorder by analyzing amino acid sequence
BMC Genomics, 2008 Background Many protein regions and some entire proteins have no definite tertiary structure, presenting instead as dynamic, disorder ensembles under different physiochemical circumstances.
Yang Mary, Yang Jack Y
doaj +1 more source
Low level sequence variant analysis of recombinant proteins: an optimized approach.
PLoS ONE, 2012 Sequence variants in recombinant biopharmaceuticals may have a relevant and unpredictable impact on clinical safety and efficacy. Hence, their sensitive analysis is important throughout bioprocess development.
Anne Zeck +10 more
doaj +1 more source
Molecular diagnosis and genetic relationship of foot and mouth disease virus serotype Asia1/Basne/Sul/2015 [PDF]
Iraqi Journal of Veterinary Sciences, 2019 Foot and Mouth Disease (FMD) is the most economically important viral-induced livestock disease worldwide. From April to May of 2015, tongue epithelial tissue samples were collected from 36 cattle in six villages, which share the border with Iran ...
Jeza Muhamad Abdul aziz +2 more
doaj +1 more source
The Amino Acid Sequence of Chromatium Ferredoxin
Journal of Biological Chemistry, 1970 The amino acid sequence of Chromatium ferredoxin was determined by studies of thermolysin peptides of S-carboxymethylcysteinylferredoxin and chymotryptic peptides of oxidized ferredoxin. The 81 amino acid residues in the molecule have the following sequence: Ala-Leu-Met-Ile-Thr-Asp-Gln-Cys-Ile-Asn-Cys-Asn-Val-Cys-Gln-Pro-Glu-Cys-Pro-Asn-Gly-Ala-Ile-Ser-
H, Matsubara +3 more
openaire +2 more sources
PrDOS: prediction of disordered protein regions from amino acid sequence
Nucleic Acids Res., 2007 PrDOS is a server that predicts the disordered regions of a protein from its amino acid sequence (http://prdos.hgc.jp). The server accepts a single protein amino acid sequence, in either plain text or FASTA format.
T. Ishida, K. Kinoshita
semanticscholar +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source