Results 11 to 20 of about 1,151,967 (219)

Word decoding of protein amino Acid sequences with availability analysis: a linguistic approach.

PLoS ONE, 2012
The amino acid sequences of proteins determine their three-dimensional structures and functions. However, how sequence information is related to structures and functions is still enigmatic.
Kenta Motomura, Tomohiro Fujita, Motosuke Tsutsumi, Satsuki Kikuzato, Morikazu Nakamura, Joji M Otaki   +5 more
doaj   +1 more source

Discovery of a Novel Member of the Carlavirus Genus from Soybean (Glycine max L. Merr.)

Pathogens, 2021
A novel member of the Carlavirus genus, provisionally named soybean carlavirus 1 (SCV1), was discovered by RNA-seq analysis of randomly collected soybean leaves in Illinois, USA.
Thanuja Thekke-Veetil, Nancy K. McCoppin, Houston A. Hobbs, Glen L. Hartman, Kris N. Lambert, Hyoun-Sub Lim, Leslie. L. Domier   +6 more
doaj   +1 more source

Analysis of two duplications of the LDL receptor gene affectingintracellular transport, catabolism, and surface binding of the LDLreceptor

Journal of Lipid Research, 1998
Two novel mutations of the low density lipoprotein (LDL)-receptor genewere found in two Italian familial hypercholesterolemia (FH)-heterozygotes. Thefirst mutation was an 18 nucleotide duplication in exon 8 which is preceded byan A→T transversion.
Dilip.D. Patel, Nicoletta Lelli, Rita Garuti, Salvatore Li Volti, Stefano Bertolini, Brian L. Knight, Sebastiano Calandra   +6 more
doaj   +1 more source

Glutathione S-transferases from the larval gut of the silkworm Bombyx mori: cDNA cloning, gene structure, expression and distribution

European Journal of Entomology, 2008
Two glutathione S-transferase (GST) cDNAs, GSTD2 and GSTS2, were cloned from the silkworm Bombyx mori. The B. mori GSTD2 (BmGSTD2) gene spans 4371 bp and consists of four introns and five exons that encode 222 amino acid residues.
Zhong Zheng GUI, Bo Yeon KIM, Kwang Sik LEE, Ya Dong WEI, Xijie GUO, Hung Dae SOHN, Byung Rae JIN   +6 more
doaj   +1 more source

Isolation and Identification of a Novel Phlebovirus, Hedi Virus, from Sandflies Collected in China

Viruses, 2021
We report the isolation of a newly recognized phlebovirus, Hedi virus (HEDV), from Phlebotomus chinensis sandflies collected in Shanxi Province, China. The virus’ RNA is comprised of three segments.
Ziqian Xu, Na Fan, Xin Hou, Jing Wang, Shihong Fu, Jingdong Song, Mang Shi, Guodong Liang   +7 more
doaj   +1 more source

Predicting the functional effect of amino acid substitutions and indels.

PLoS ONE, 2012
As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being developed to provide computational predictions on the functional effects of sequence variations and narrow down the search of ...
Yongwook Choi, Gregory E Sims, Sean Murphy, Jason R Miller, Agnes P Chan   +4 more
doaj   +1 more source

Sequence variation of the HVR1 region of Hepatitis C virus in response to interferon-α and ribavirin treatment

Journal of Infection in Developing Countries, 2011
Introduction: Hepatitis C virus (HCV), which is a major cause of liver diseases worldwide, undergoes genetic variation during the course of infection. The aim of this study was to examine sequence variations within the HVR1 region of HCV genotype 4 in ...
Ahmed Ali Al-Qahtani, Salvatore Rubino, Mohammed N. Al-Ahdal   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Amino acid classification based spectrum kernel fusion for protein subnuclear localization

BMC Bioinformatics, 2010
Background Prediction of protein localization in subnuclear organelles is more challenging than general protein subcelluar localization. There are only three computational models for protein subnuclear localization thus far, to the best of our knowledge.
Fei Wang, Mei Suyu
doaj   +1 more source

Molecular diagnosis and genetic relationship of foot and mouth disease virus serotype Asia1/Basne/Sul/2015 [PDF]

Iraqi Journal of Veterinary Sciences, 2019
Foot and Mouth Disease (FMD) is the most economically important viral-induced livestock disease worldwide. From April to May of 2015, tongue epithelial tissue samples were collected from 36 cattle in six villages, which share the border with Iran ...
Jeza Muhamad Abdul aziz, Salih Hama, Hawre Kamel Faraj   +2 more
doaj   +1 more source