Results 41 to 50 of about 1,115,659 (268)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Arquivos de GastroenterologiaBackground - Exposure to viral antigens that share amino acid sequence similar with self- antigens might trigger autoimmune diseases in genetically predisposed individuals, and the molecular mimicry theory suggests that epitope mimicry between the virus ...
Maristella de Araújo Carvalho SOUSA +2 more
doaj +1 more source
Predicting DNA-binding sites of proteins from amino acid sequence
BMC Bioinformatics, 2006 Background Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach for the identification of amino acid residues involved in protein-DNA ...
Wu Feihong +5 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Protein sequence alignment with family-specific amino acid similarity matrices
BMC Research Notes, 2011 Background Alignment of amino acid sequences by means of dynamic programming is a cornerstone sequence comparison method. The quality of alignments produced by dynamic programming critically depends on the choice of the alignment scoring function ...
Kuznetsov Igor B
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The Amino Acid Sequence of Bovine Adrenodoxin
Journal of Biological Chemistry, 1973 Abstract The preliminary amino acid sequence of bovine adrenodoxin previously reported from our laboratory has been shown to be in error. In the corrected sequence, adrenodoxin contains 114 amino acid residues. The residues Asx-Glx-Leu in position 78, 79, and 80 and the aspartic acid residue in position 107 should be deleted from the previously ...
M, Tanaka +3 more
openaire +2 more sources
Completion of the amino acid sequence of papain [PDF]
Biochemical Journal, 1969 Papain was inhibited with bromo[2−14C]acetic acid, the tertiary structure of the inhibited enzyme was unfolded and the disulphide bridges were reduced with mercaptoethanol and aminoethylated. Digestion with trypsin gave a radioactive peptide consisting of residues 18–58 inclusive and containing therefore the sequence of the thirteen unknown residues 29–
S S, Husain, G, Lowe
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Amino acid impact factor. [PDF]
PLoS ONE, 2018 Amino acid mutations in proteins are random and those mutations which are beneficial or neutral survive during the course of evolution. Conservation or co-evolution analyses are performed on the multiple sequence alignment of homologous proteins to ...
C K Sruthi, Meher Prakash
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source