Results 41 to 50 of about 1,719,666 (251)

SSE: a nucleotide and amino acid sequence analysis platform

BMC Research Notes, 2012
Background There is an increasing need to develop bioinformatic tools to organise and analyse the rapidly growing amount of nucleotide and amino acid sequence data in organisms ranging from viruses to eukaryotes.
Simmonds Peter
doaj   +1 more source

Reading the three-dimensional structure of a protein from its amino acid sequence

, 2000
While all the information required for the folding of a protein is contained in its amino acid sequence, one has not yet learnt how to extract this information so as to predict the detailed, biological active, three-dimensional structure of a protein ...
Broglia, R. A., Tiana, G.
core   +1 more source

The Amino Acid Sequence of Chromatium Ferredoxin

Journal of Biological Chemistry, 1970
The amino acid sequence of Chromatium ferredoxin was determined by studies of thermolysin peptides of S-carboxymethylcysteinylferredoxin and chymotryptic peptides of oxidized ferredoxin. The 81 amino acid residues in the molecule have the following sequence: Ala-Leu-Met-Ile-Thr-Asp-Gln-Cys-Ile-Asn-Cys-Asn-Val-Cys-Gln-Pro-Glu-Cys-Pro-Asn-Gly-Ala-Ile-Ser-
H, Matsubara, R M, Sasaki, D K, Tsuchiya, M C, Evans   +3 more
openaire   +2 more sources

Incorporating background frequency improves entropy-based residue conservation measures

BMC Bioinformatics, 2006
Background Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may correlate with structurally or functionally important residues.
Samudrala Ram, Wang Kai
doaj   +1 more source

SEQUENCE SIMILARITY BETWEEN THYROID SELF-PROTEIN AND HEPATITIS C VIRUS POLYPROTEIN: possible triggering mechanism of autoimmune thyroiditis

Arquivos de Gastroenterologia
Background - Exposure to viral antigens that share amino acid sequence similar with self- antigens might trigger autoimmune diseases in genetically predisposed individuals, and the molecular mimicry theory suggests that epitope mimicry between the virus ...
Maristella de Araújo Carvalho SOUSA, Raymundo PARANÁ, Luís Jesuíno de Oliveira ANDRADE   +2 more
doaj   +1 more source

Predicting DNA-binding sites of proteins from amino acid sequence

BMC Bioinformatics, 2006
Background Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach for the identification of amino acid residues involved in protein-DNA ...
Wu Feihong, Terribilini Michael, Yan Changhui, Jernigan Robert L, Dobbs Drena, Honavar Vasant   +5 more
doaj   +1 more source

The Amino Acid Sequence of Bovine Adrenodoxin

Journal of Biological Chemistry, 1973
Abstract The preliminary amino acid sequence of bovine adrenodoxin previously reported from our laboratory has been shown to be in error. In the corrected sequence, adrenodoxin contains 114 amino acid residues. The residues Asx-Glx-Leu in position 78, 79, and 80 and the aspartic acid residue in position 107 should be deleted from the previously ...
M, Tanaka, M, Haniu, K T, Yasunobu, T, Kimura   +3 more
openaire   +2 more sources

Protein sequence alignment with family-specific amino acid similarity matrices

BMC Research Notes, 2011
Background Alignment of amino acid sequences by means of dynamic programming is a cornerstone sequence comparison method. The quality of alignments produced by dynamic programming critically depends on the choice of the alignment scoring function ...
Kuznetsov Igor B
doaj   +1 more source

Exploring the Levinthal limit in protein folding [PDF]

, 2017
According to the thermodynamic hypothesis, the native state of proteins is uniquely defined by their amino acid sequence. On the other hand, according to Levinthal, the native state is just a local minimum of the free energy and a given amino acid ...
B Fazi, B Hess, C Anfınsen, C Levinthal, C Orengo, D Baker, D Case, D van der Spoel, H Berman, H Gouda, J Sohl, JD Bryngelson, K Dill, L Cruzeiro, L Cruzeiro, L Cruzeiro, Leonor Cruzeiro, Léo Degrève, P Gettins, T Gallagher, T Lazaridis, TR Hynes, W Humphrey, W van Gunsteren   +23 more
core   +1 more source

Application of amino acid occurrence for discriminating different folding types of globular proteins

BMC Bioinformatics, 2007
Background Predicting the three-dimensional structure of a protein from its amino acid sequence is a long-standing goal in computational/molecular biology.
Gromiha M Michael, Taguchi Y-h
doaj   +1 more source