Results 1 to 10 of about 2,639,770 (162)

Influence of Leucine on Protein Metabolism of Chicken Embryo Myoblasts is Modulated by Varying Serum Concentrations in the Medium

The Journal of Poultry Science, 2007
The influence of varying leucine and fetal calf serum (FCS) concentrations in the culture medium on protein synthesis and degradation of chicken embryo myoblasts was examined.
Mai Oki, Hiroyuki Sato, Kazuki Nakagawa, Kazumi Kita   +3 more
doaj   +1 more source

Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases

Proteomes, 2015
Probing the dynamic activities of protein kinases in real-time in living cells constitutes a major challenge that requires specific and sensitive tools tailored to meet the particular demands associated with cellular imaging.
Juan A. González-Vera, May C. Morris
doaj   +1 more source

Variants of the industrially relevant protease KP-43 with suppressed activity under alkaline conditions developed using expanded genetic codes

Biochemistry and Biophysics Reports, 2019
In the present study, we attempted to control the pH profile of the catalytic activity of the industrially relevant alkaline protease KP-43, by incorporating 3-nitro-l-tyrosine and 3-chloro-l-tyrosine at and near the catalytic site. Thirty KP-43 variants
Tatsuya Osamura, Mitsuyoshi Okuda, Atsushi Yamaguchi, Kazumasa Ohtake, Kensaku Sakamoto, Yasushi Takimura   +5 more
doaj   +1 more source

Dietary L-glutamate modulates intestinal mucosal immunity of juvenile hybrid striped bass (Morone saxatilis ♀ × Morone chrysops ♂)

Frontiers in Immunology
IntroductionL-Glutamate is a conditionally essential amino acid, meaning it can become essential under specific conditions, like stress or disease. It is an abundant intracellular amino acid crucial in immune responses.
Karina L. Hissen, Wenliang He, Guoyao Wu, Michael F. Criscitiello, Michael F. Criscitiello   +4 more
doaj   +1 more source

Evaluation of the antimicrobial-cytotoxic activities and molecular docking study of L-cysteine ethyl ester and L-cysteine methyl ester

Amino Acids
Antibiotic resistance is a growing problem in the treatment of life-threatening diseases. Recently, a variety of covalent drugs have emerged. Cysteine ​​is one of the least abundant amino acids in the proteins of many organisms, and the thiol group in ...
Tuğçe Deniz Karaca, Hüseyin Balcı, Arzu Aysan, Yusuf Sert, Alev Doğan   +4 more
doaj   +1 more source

NGS and the design of an optimized phage display workflow for peptide discovery

Amino Acids
Phage display is a powerful technology that has demonstrated great potential in identifying peptides with high binding affinity and specificity toward a broad spectrum of biological targets. The undesired enrichment of nonspecific binders remains a major
Babak Bakhshinejad, Andreas Kjaer
doaj   +1 more source

Rational designing and synthesizing an antimicrobial peptide from bovine milk casein and evaluating its biological properties

Amino Acids
The overuse of antibiotics has led to a growing crisis—antimicrobial resistance, making it harder to treat infections and pushing scientists to find new solutions.
Seyed Reza Pourhosseini, Bahman Akbari, Elahe Ghods, Kamal Veisi, Hamid Madanchi   +4 more
doaj   +1 more source

Transport of the uremic toxin symmetric dimethylarginine (SDMA) by renal transport proteins

Amino Acids
The L-arginine derivative and uremic toxin symmetric dimethylarginine (SDMA) is an independent risk marker for total mortality and cardiovascular events.
Lorenz A. Scherpinski, Martin F. Fromm, Renke Maas, Jörg König   +3 more
doaj   +1 more source

Essential amino acid supplementation for pressure ulcers: pathophysiological rationale and results from a pilot study

Amino Acids
Pressure ulcers (PU) are a major and serious problem affecting millions of people. Malnutrition, frequently co-occurring with PU, is considered modifiable risk factor, and dietary supplements currently recommended for supporting PU healing contain a high
Maciej Świątkiewicz, Andrzej Lejczak, Piotr Foltyński, Paweł Grieb   +3 more
doaj   +1 more source

Enhanced γ-aminobutyric acid levels promote degeneration of silk glands following spermidine supplementation in Bombyx mori

Amino Acids
Silk glands are modified labial glands that produce silk which has immense commercial importance. Silk is extruded out in liquid form after which the glands undergo autophagy and apoptosis during larval to pupal transition.
Brinda Goda Lakshmi Didugu, Anitha Mamillapalli   +1 more
doaj   +1 more source