Results 41 to 50 of about 2,639,770 (162)

Mild and effective N-phthaloylation of amino acids

, 2004
In the present work various free amino acids, including tryptophan and tyrosine, were effectively N-phthaloylated under reduced pressure and at lower temperature.
Liu, Z, 曾庆乐, Zeng, Q, Li, B, Wang, F   +4 more
core  

L-tyrosine inhibits the formation of amyloid fibers of human lysozyme at physiological pH and temperature

Amino Acids
Amyloid fibers are implicated in numerous diseases, making their study crucial for identifying effective therapeutic compounds. This research highlights the ability of L-tyrosine to inhibit the formation of amyloid fibers in human lysozyme.
Santos López, Arturo Rojo-Domínguez, Roxana López-Simeon, Alejandro Sosa-Peinado, Hugo Nájera   +4 more
doaj   +1 more source

Exploring the therapeutic potential of L-arginine in chronic anal fissure management: a comprehensive review

Amino Acids
Anal fissure causes pain and bleeding during or after bowel movements, significantly impacting individuals’ quality of life. Current treatments aim to interrupt this cycle but have associated risks and limitations.
Nogol Motamed-Gorji, Mohsen Masoodi, Masoumeh Khalighi Sikaroudi, Shahram Agah, Nikta Masoodi   +4 more
doaj   +1 more source

Diel rhythmicity in amino acid uptake by Prochlorococcus [PDF]

, 2008
The marine cyanobacterium Prochlorococcus, the most abundant phototrophic organism on Earth, numerically dominates the phytoplankton in nitrogen (N)-depleted oceanic gyres.
Terry, Matthew J, Garczarek, Laurence, Tarran, Glen A, Mary, Isabelle, Burkill, Peter H, Scanlan, David J, Kolowrat, Christian, Zubkov, MV, Zubkov, Mikhail V, Terry, MJ, Tarran, Glen A., Scanlan, David J., Scanlan, DJ, Burkill, Peter H., Tarran, GA, Terry, Matthew J., Burkill, PH, Zubkov, Mikhail V., Kolowrat, CK, Mary, I, Garczarek, LG   +20 more
core   +1 more source

MTR4 methylation-dependent degradation activates mTORC1 signaling to promote glioma cell survival under methionine starvation

Amino Acids
Methionine is an essential amino acid for the human body. Understanding how tumor cells adjust their signaling networks to evade apoptosis and sustain proliferation in a methionine starvation tumor microenvironment is a significant scientific question ...
Lude Wang, Qiuwen Lou, Jie Chang, Zhijian Xu, Fan Yang, Qi Tu, Jianmin Zhang, Wenxia Xu, Minfeng Tong   +8 more
doaj   +1 more source

Probiotic and microbial modulation of polyamine production: an emerging avenue for neuroprotection in neurodegenerative disorders

Amino Acids
Neurodegenerative disorders are an Critical worldwide issue, characterized by progressive neuronal loss and cognitive decline with limited effective therapies.
Tushar Adhikari, Prerona Saha
doaj   +1 more source

Biocompatible silver nanoparticles prepared with amino acids and a green method

, 2017
The synthesis of nanoparticles is usually carried out by chemical reduction, which is effective but uses many toxic substances, making the process potentially harmful to the environment.
de Matos, Ricardo Almeida [UNIFESP], Courrol, Lilia Coronato [UNIFESP]   +1 more
core   +1 more source

Targeting amino acid metabolic pathways: a novel therapeutic strategy for hyperuricemia-associated complications

Amino Acids
Hyperuricemia (HUA) is a metabolic disorder that contributes to the pathogenesis of gout arthritis (GA), chronic kidney disease (CKD), and cardiovascular disease (CVD).
Xinya Zhang, Wenkai Wang, Le Yang, Ye Sun, Hui Sun, Xueping Zhao, Hui Sun, Guangli Yan, Xijun Wang   +8 more
doaj   +1 more source

Mechanisms of insulin secretion in malnutrition: modulation by amino acids in rodent models

, 2010
Protein restriction at early stages of life reduces beta-cell volume, number of insulin-containing granules, insulin content and release by pancreatic islets in response to glucose and other secretagogues, abnormalities similar to those seen in type 2 ...
Machado de Oliveira, Camila Aparecida, Latorraca, Marcia Queiroz, Oliveira, Camila Aparecida Machado de [UNIFESP], Carneiro, Everardo Magalhaes, Rostom de Mello, Maria Alice, Rostom de Mello, Maria Alice [UNESP], Carneiro E.M., de Oliveira, Camila Aparecida Machado, Márcia Queiroz Latorraca, Everardo Magalhães Carneiro, de Mello, Maria Alice Rostom, De Mello M.A.R., De Oliveira C.A.M., Camila Aparecida Machado de Oliveira, Latorraca M.Q., Maria Alice Rostom de Mello   +15 more
core   +1 more source

Maternal dietary citrulline supplementation increases fetal growth and programs pancreatic development in the lambs

Amino Acids
Intrauterine growth restriction (IUGR), caused by maternal undernutrition, impairs fetal growth and increases the risk for postnatal metabolic dysfunction.
Alissa B. Herring, Kyle S. Herron, London G. Lemcke, Gregory A. Johnson, M. Carey Satterfield   +4 more
doaj   +1 more source