Results 41 to 50 of about 8,623,839 (302)

Lysine malonylation as a therapeutic target: implications for metabolic, inflammatory, and oncological disorders

open access: yesAmino Acids
Lysine malonylation (Kmal) is an emerging posttranslational modification (PTM) intricately linked to cellular metabolism and disease pathogenesis. This review explores the regulatory mechanisms of Kmal, emphasizing the role of malonyl-CoA as its donor ...
Ahsanullah Unar
doaj   +1 more source

Therapeutic peptides: chemical strategies fortify peptides for enhanced disease treatment efficacy

open access: yesAmino Acids
Therapeutic peptides, as a unique form of medication composed of orderly arranged sequences of amino acids, are valued for their high affinity, specificity, low immunogenicity, and economical production costs.
Qingmei Li, Wen Chao, Lijuan Qiu
doaj   +1 more source

Aqueous Amino Acids and Proteins Near the Surface of Gold in Hydrophilic and Hydrophobic Force Fields [PDF]

open access: yes, 2014
We calculate potentials of the mean force for twenty amino acids in the vicinity of the (111) surface of gold, for several dipeptides, and for some analogs of the side chains, using molecular dynamics simulations and the umbrella sampling method.
Cieplak, Marek, Nawrocki, Grzegorz
core   +1 more source

Safety assessment of L-ornithine oral intake in healthy subjects: a systematic review

open access: yesAmino Acids
L-Ornithine (L-Orn) is a nonessential amino acid but has many physiological roles. Accordingly, L-Orn has been used as a functional food or dietary supplement to ameliorate various maladies, but there is only limited information available about its ...
Hyemin Yang   +4 more
doaj   +1 more source

Amino acid analysis [PDF]

open access: yes, 1974
The process and apparatus for qualitative and quantitative analysis of the amino acid content of a biological sample are presented. The sample is deposited on a cation exchange resin and then is washed with suitable solvents.
Graff, J., Winitz, M.
core   +1 more source

The Impact of Capsid Proteins on Virus Removal and Inactivation During Water Treatment Processes [PDF]

open access: yes, 2015
This study examined the effect of the amino acid composition of protein capsids on virus inactivation using ultraviolet (UV) irradiation and titanium dioxide photocatalysis, and physical removal via enhanced coagulation using ferric chloride.
Abbaszadegan, Morteza A.   +3 more
core   +3 more sources

The effect of L-Arg supplementation on L-Arg/NO metabolic and AMPK/ACC-1 signalling pathways in adipose cells (3T3 L1)

open access: yesAmino Acids
L-arginine (L-Arg) is metabolised in the cell to generate nitric oxide (NO) and citrulline via nitric oxide synthase (NOS). NO is an important cellular signalling molecule that regulates lipid and glucose metabolism.
Saranya Prashath
doaj   +1 more source

The d-amino acid oxidase of Neurospora [PDF]

open access: yes, 1944
Among artificially produced mutants of the mold Neurospora have been found strains lacking the ability to synthesize specific amino acids (1, 2). In the course of biochemical and genetic studies of this group of mutants it was observed that some of the ...
Horowitz, N. H.
core  

Nature's Starships II: Simulating the Synthesis of Amino Acids in Meteorite Parent Bodies

open access: yes, 2015
Carbonaceous chondrite meteorites are known for having high water and organic material contents, including amino acids. Here we address the origin of amino acids in the warm interiors of their parent bodies (planetesimals) within a few million years of ...
Cobb, Alyssa K.   +2 more
core   +1 more source

Review

open access: yes, 2020
The chalcogen elements oxygen, sulfur, and selenium are essential constituents of side chain functions of natural amino acids. Conversely, no structural and biological function has been discovered so far for the heavier and more metallic tellurium ...
Agh R   +13 more
core   +1 more source

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