Results 51 to 60 of about 2,639,770 (162)

At the core of global bioenergy: polyamines and transglutaminases in chloroplasts

Amino Acids
Chloroplasts are the energy factories of photosynthetic life. The energy and the plant biomass of the planet depend on the activity of chloroplasts. Their efficiency results from a delicate balance between membrane organization, metabolic regulation and ...
Donatella Serafini-Fracassini, Stefano Del Duca   +1 more
doaj   +1 more source

Revisiting the antizyme 1 – ODC interaction reveals low-nanomolar affinity

Amino Acids
Ornithine decarboxylase (ODC) catalyzes the rate-limiting step in polyamine biosynthesis and is one of the shortest-lived mammalian proteins. Its activity and proteasomal degradation are controlled by antizyme (AZ), which disrupts the active ODC ...
Grzegorz P. Bereta, Elżbieta Wątor-Wilk, Paweł Kochanowski, Jakub Nowak, Tomasz Kantyka, Przemysław Grudnik   +5 more
doaj   +1 more source

Taurine supplementation and systemic lupus erythematosus in preclinical studies: a systematic review of clinical outcomes and underlying mechanisms

Amino Acids
Taurine (Tau) is a sulfur-containing amino acid that has therapeutic roles in several diseases, including inflammatory conditions. The involvement of Tau in modulating systemic lupus erythematosus (SLE) autoimmunity has been indicated in preclinical ...
Aida Malek Mahdavi, Zeinab Javadivala, Niloufar Orooji   +2 more
doaj   +1 more source

4 Aromatic Amino Acids in the Brain

, 2007
This chapter describes the aromatic l-amino acids tryptophan and tyrosine and the effects on tyrosine metabolism of phenylalanine. Tryptophan and phenylalanine are essential amino acids and must ultimately be derived from dietary proteins; tyrosine is ...
M. Cansev, Cansev, Mehmet, R. J. Wurtman, Wurtman, Richard J.   +3 more
core   +1 more source

The role of N-acetylcysteine and glutathione in the management of Parkinson’s disease: a systematic review of oxidative biomarkers and clinical outcomes

Amino Acids
Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterised by the loss of dopaminergic neurons, leading to both motor and non-motor symptoms.
Imran Mohammed, Yasimin Nankya, U. Teng Hong, Amy Kan, Alya Masoud Abdelhafid, Gladys O. Latunde-Dada   +5 more
doaj   +1 more source

The synthesis of substituted phosphonic acids [PDF]

Cyclic phosphonic acid analogues of the endogenous amino acids L-aspartic acid and L -glutamic acid have played a major role in the characterisation of excitatory amino acid receptors in the central nervous system. The aim of the first section of this
Hanrahan, Jane
core  

Enzymatic detection of D-amino acids

, 2011
D: -Amino acids play several key roles and are widely diffused in living organisms, from bacteria (in which D-alanine is a component of the cell wall) to mammals (where D-serine is involved in glutamatergic neurotransmission in the central nervous system)
VOLONTÈ, FEDERICA, Gianluca Molla, Mirella S. Pilone, Pilone, M. S., Federica Volontè, Luciano Piubelli, MOLLA, GIANLUCA, PIUBELLI, LUCIANO   +7 more
core   +1 more source

Regulatory effects of blood constituents on the function and metabolism of the cat brain in perfusion ezperiments. Brain perfusion with artificial blood containing low molecular dextran and amino acids [PDF]

, 1967
As a link in a series of studies on the effects of blood constituents on the brain function by means of brain perfusion, we used four kinds of artificial blood; namely, the blood containing a low molecular dextran, one containing glutamic acid, one ...
Nakashima, Yoshihiko, Watanabe, Shosuke, Okumura, Nikichi, Edamatsu, Kazuyasu, Otsuki, Saburo, Morimitsu, Junsuke   +5 more
core   +1 more source

Adaptive crosstalk between polyamine metabolism, translation, and autophagy sustains energy homeostasis in mammals during starvation: a scoping review

Amino Acids
Mammalian cells tightly regulate the shift between catabolism and anabolism to maintain energy homeostasis during starvation. Among other adaptations, cells adapt to nutrient restriction by downregulating translation, the most energy consuming cellular ...
Kayhan Karimi, Sigrid C. Roberts, Nicola S. Carter, Sebastian J. Hofer, Reza Karimi   +4 more
doaj   +1 more source

Enantiopure b3-amino acids-2,2-d2 via homologation of proteinogenic a-amino acids

, 2007
A procedure for the synthesis of enantiopure β3-amino acids from proteinogenic α-amino acids, developed by our group a few years ago, has been modified to enable the production of C-2 fully deuterated, C-protected β3-amino acids and, even more important,
CAPUTO, ROMUALDO, LONGOBARDO, LUIGI
core   +1 more source