Results 61 to 70 of about 2,639,770 (162)

PCLPred: identifying plant chloride transport-related proteins using reduced amino acid alphabets and N-peptide composition

Amino Acids
Chloride transport-related proteins play critical roles in coordinating ion cycling, maintaining cellular homeostasis, and enabling plants to dynamically adapt to environmental changes, particularly under salt stress conditions.
Ge Bai, Lijia Liu, Hui Zhang, Ruimei Geng, Yong Li, Dahai Yang, Mingliang Fei, Tao Pang, Hao Wang, Aiguo Yang, He Xie, Hao Eang   +11 more
doaj   +1 more source

Creatine homeostasis and the kidney: comparison between kidney transplant recipients and healthy controls

Amino Acids
Creatine is a natural nitrogenous organic acid that is integral to energy metabolism and crucial for proper cell functioning. The kidneys are involved in the first step of creatine production. With kidney transplantation being the gold-standard treatment
Adrian Post, Dion Groothof, Daan Kremer, Tim J. Knobbe, Willem Abma, Christa A. Koops, Dimitrios Tsikas, Theo Wallimann, Robin P.F. Dullaart, Casper F.M. Franssen, Ido P. Kema, M. Rebecca Heiner-Fokkema, Stephan J.L. Bakker   +12 more
doaj   +1 more source

Sex differences in amino acids lost via sweating could lead to differential susceptibilities to disturbances in nitrogen balance and collagen turnover

, 2017
Fluid collected during sweating is enriched with amino acids derived from the skin’s natural moisturising factors and has been termed “faux” sweat. Little is known about sex differences in sweat amino acid composition or whether faux sweat amino acid ...
Stevens, Christopher J, T. K. Roberts, Gottfries, C G, Dunstan, R H, Sparkes, D L, J. Gottfries, R. H. Dunstan, Murphy, G. R., Gottfries, J, M. M. Macdonald, Murphy, G R, Gottfries, J., Dascombe, Ben (R21089), C.-G. Gottfries, Roberts, T K, Sparkes, D. L., Stevens, Christopher J., C. J. Stevens, Dascombe, B. J., Gottfries, C. G., B. J. Dascombe, Dascombe, B J, Macdonald, M. M., Stevens, C. J., Dunstan, R. H., Roberts, T. K., Macdonald, M M, Gottfries, Johan,, D. L. Sparkes, Gottfries, C.-G., G. R. Murphy   +30 more
core   +1 more source

Exploring the interplay between kidney function and urinary metabolites in young adults: the African-PREDICT study

Amino Acids
The exposure to modifiable risk factors at young ages have been linked to premature fatal and non-fatal cardiovascular and kidney outcomes. The use of urinary metabolomics has shown strong predictability of kidney function and cardiovascular disease (CVD)
Wessel L. du Toit, Ruan Kruger, Lebo F. Gafane-Matemane, Aletta E. Schutte, Roan Louw, Catharina M. C. Mels   +5 more
doaj   +1 more source

In vitro and in vivo studies on exogenous polyamines and α-difluoromethylornithine to enhance bone formation and suppress osteoclast differentiation

Amino Acids
Exogenous polyamines, including putrescine (PUT), spermidine (SPD), and spermine (SPM), and the irreversible inhibitor of the rate-limiting enzyme ornithine decarboxylase (ODC) of polyamine biosynthesis, α-difluoromethylornithine (DFMO), are implicated ...
Chien-Ching Lee, Chia-Chun Chuang, Chung-Hwan Chen, Yuan-Pin Huang, Chiao-Yi Chang, Pei-Yi Tung, Mon-Juan Lee   +6 more
doaj   +1 more source

Prediction of matrilineal specific patatin-like protein governing in-vivo maternal haploid induction in maize using support vector machine and di-peptide composition

Amino Acids
The mutant matrilineal (mtl) gene encoding patatin-like phospholipase activity is involved in in-vivo maternal haploid induction in maize. Doubling of chromosomes in haploids by colchicine treatment leads to complete fixation of inbreds in just one ...
Suman Dutta, Rajkumar U. Zunjare, Anirban Sil, Dwijesh Chandra Mishra, Alka Arora, Nisrita Gain, Gulab Chand, Rashmi Chhabra, Vignesh Muthusamy, Firoz Hossain   +9 more
doaj   +1 more source

d-Amino acids differentially trigger an inflammatory environment in vitro

Amino Acids
Studies in vivo have demonstrated that the accumulation of d-amino acids (d-AAs) is associated with age-related diseases and increased immune activation. However, the underlying mechanism(s) of these observations are not well defined. The metabolism of d-
Siew Hwei Yap, Cheng Siang Lee, Nur Diyana Zulkifli, Darshinie Suresh, Kenji Hamase, Kumitaa Theva Das, Reena Rajasuriar, Kok Hoong Leong   +7 more
doaj   +1 more source

The reverse transsulfuration pathway affects the colonic microbiota and contributes to colitis in mice

Amino Acids
Cystathionine γ-lyase (CTH) is a critical enzyme in the reverse transsulfuration pathway, the major route for the metabolism of sulfur-containing amino acids, notably converting cystathionine to cysteine.
Alain P. Gobert, Yvonne L. Latour, Kara M. McNamara, Caroline V. Hawkins, Kamery J. Williams, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Alberto G. Delgado, Ginger L. Milne, Shilin Zhao, M. Blanca Piazuelo, M. Kay Washington, Lori A. Coburn, Keith T. Wilson   +14 more
doaj   +1 more source

A novel ACE inhibitory peptide from Pelodiscus sinensis Wiegmann meat water-soluble protein hydrolysate

Amino Acids
Pelodiscus sinensis meat is a nutritional food and tonic with angiotensin-converting enzyme (ACE) inhibitory activities. To identify the bioactive substances responsible, several bioinformatics methods were integrated to enable a virtual screening for ...
Pengying Liao, Huayu Liu, Xueqin Sun, Xinrui Zhang, Miao Zhang, Xianyou Wang, Jun Chen   +6 more
doaj   +1 more source

Taurine ameliorates sensorimotor function by inhibiting apoptosis and activating A2 astrocytes in mice after subarachnoid hemorrhage

Amino Acids
Subarachnoid hemorrhage (SAH) is a form of severe acute stroke with very high mortality and disability rates. Early brain injury (EBI) and delayed cerebral ischemia (DCI) contribute to the poor prognosis of patients with SAH.
Chunlei Yang, Zhiwen Jiang, Xinjie Gao, Heng Yang, Jiabin Su, Ruiyuan Weng, Wei Ni, Yuxiang Gu   +7 more
doaj   +1 more source