Results 71 to 80 of about 2,639,770 (162)

Alanine, a potential amino acid biomarker of pediatric sepsis: a pilot study in PICU

Amino Acids
Sepsis is characterized by a metabolic disorder of amino acid occurs in the early stage; however, the profile of serum amino acids and their alterations associated with the onset of sepsis remain unclear.
Tiantian Liu, Yaya Xu, Shaohua Hu, Shuyun Feng, Hong Zhang, Xiaodong Zhu, Chunxia Wang   +6 more
doaj   +1 more source

Evaluation of supplementary carnosine accumulation and distribution: an initial analysis of participants in the Nucleophilic Defense Against PM Toxicity (NEAT) clinical trial

Amino Acids
Carnosine is an endogenous dipeptide that buffers intracellular pH and quenches toxic products of lipid peroxidation. Used as a dietary supplement, it also supports exercise endurance.
Shahid P. Baba, Alok R. Amraotkar, David Hoetker, Hong Gao, Daniel Gomes, Jingjing Zhao, Michael F. Wempe, Peter J. Rice, Andrew P. DeFilippis, Shesh N. Rai, C. Arden Pope, Aruni Bhatnagar, Timothy E. O’Toole   +12 more
doaj   +1 more source

Serum amino acid profile in patients with acute pancreatitis

, 2008
Patients in the early phase of acute pancreatitis (AP) have reduced serum levels of arginine and citrulline. This may be of patho-biological importance, since arginine is the substrate for nitric oxide, which in turn is involved in normal pancreatic ...
Trulsson, Lena,, Gasslander, Thomas,, Sundqvist, Tommy,, von Dobeln, U.,, Svanvik, Joar,, Sandström, Per,, Sundqvist, T, von, Dobeln U, Svanvik, J, Trulsson, L, Gasslander, T, Sandstrom, P   +11 more
core   +1 more source

Green synthesis of self-oriented flower-like Ag@Ag2O nanostructures functionalized with L-Tryptophan for colorimetric simultaneous determination of ultra-trace level of thiamin and riboflavin

Amino Acids
The study focuses on the green synthesis of Ag@Ag2O nanostructures using Padina algae extract and functionalizing them with L-tryptophan to enhance their properties as a colorimetric sensor for simultaneous detection of ultra-trace levels of thiamin and ...
Maryam Abbasi Tarighat, Zahra Khosravani, Gholamreza Abdi   +2 more
doaj   +1 more source

Structure-activity relationship of amino acid analogs to probe the binding pocket of sodium-coupled neutral amino acid transporter SNAT2

Amino Acids
The sodium-coupled neutral amino acid transporter SNAT2 (SLC38A2) has been shown to have important physiological functions and is implicated in various diseases like cancer.
Sebastian Jakobsen, Maria Pedersen, Carsten Uhd Nielsen   +2 more
doaj   +1 more source

Effect of oxygen tension on the amino acid utilisation of human embryonic stem cells

, 2014
Background/aims: human embryonic stem cells (hESCs) are a potential source of cells for treatment of many degenerative diseases, but in culture have a propensity to spontaneously differentiate, possibly due to suboptimal conditions. Culture at low oxygen
Christensen, David R., David R. Christensen, Calder, Philip C., Houghton, Franchesca D., Philip C. Calder, Franchesca D. Houghton   +5 more
core   +1 more source

Pharmacokinetics of L-theanine and the effect on amino acid composition in mice administered with L-theanine

Amino Acids
L-theanine, an amino acid component of the tea leaves of Camellia sinensis, is sold in Japan as a supplement for good sleep. Although several studies in humans and mice have reported the effects of L-theanine on brain function, only a few reports have ...
Shinnosuke Yamaura, Koki Sadamori, Reiko Konishi, Takashi Majima, Akira Mukai, Kyosuke Uno, Toshihiko Kinjo, Koji Komori, Nobuyuki Kuramoto, Kou Kawada   +9 more
doaj   +1 more source

Identification and characterization of endogenous biomarkers for hepatic vectorial transport (OATP1B3-P-gp) function using metabolomics with serum pharmacology

Amino Acids
The organic anion-transporting polypeptide 1B3 and P-glycoprotein (P-gp) provide efficient directional transport (OATP1B3-P-gp) from the blood to the bile that serves as a key determinant of hepatic disposition of the drug.
Yong-wen Jin, Yan-rong Ma, Ming-kang Zhang, Wen-bin Xia, Pei Yuan, Bo-xia Li, Yu-hui Wei, Xin-an Wu   +7 more
doaj   +1 more source

Tetrahydrofuran Amino Acids of the Past Decade

Review: syntheses of THF α-, β-, γ-, δ- and longer chain amino acids; 78 ...
Turks, Māris, Rjabovs, Vitālijs
core  

Order of amino acids in C-terminal cysteine-containing peptide-based chelators influences cellular processing and biodistribution of 99mTc-labeled recombinant Affibody molecules

, 2011
Affibody molecules constitute a novel class of molecular display selected affinity proteins based on non-immunoglobulin scaffold. Preclinical investigations and pilot clinical data have demonstrated that Affibody molecules provide high contrast imaging ...
Altai, Mohamed,, Wållberg, Helena, Rosestedt, Maria,, Helena Wållberg, Hosseinimehr, Seyed Jalal,, Vladimir Tolmachev, Tolmachev, Vladimir, Maria Rosestedt, Stefan Ståhl, Tolmachev, Vladimir,, Rosestedt, Maria, Ståhl, Stefan,, Mohamed Altai, Orlova, Anna, Wållberg, Helena,, Hosseinimehr, Seyed Jalal, Orlova, Anna,, Anna Orlova, Ståhl, Stefan, Altai, Mohamed, Seyed Jalal Hosseinimehr   +20 more
core   +1 more source