Results 41 to 50 of about 78,014 (306)

Anti-BIRC5 autoantibody serves as a valuable biomarker for diagnosing AFP-negative hepatocellular carcinoma [PDF]

PeerJ
Background Autoantibodies targeting tumor-associated antigens (TAAbs) have emerged as promising biomarkers for early cancer detection. This research aimed to assess the diagnostic capacity of anti-BIRC5 autoantibody in detecting AFP-negative ...
Qing Li, Haiyan Liu, Han Wang, Wenzhuo Xiong, Liping Dai, Xiuzhi Zhang, Peng Wang, Hua Ye, Jianxiang Shi, Zhihao Fang, Keyan Wang   +10 more
doaj   +2 more sources

Case report: Amnestic mild cognitive impairment in multiple domains associated with neurofascin 186 autoantibodies: Case series with follow-up and review

Frontiers in Psychiatry, 2023
BackgroundNeurofascin 186 autoantibodies are known to occur with a diseased peripheral nervous system. Recently, also additional central nervous system (CNS) involvement has been reported in conjunction with neurofascin 186 autoantibodies.
Niels Hansen, Niels Hansen, Anne Sagebiel, Kristin Rentzsch, Sina Hirschel, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Björn H. Schott, Björn H. Schott, Björn H. Schott, Bartels Claudia   +11 more
doaj   +1 more source

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes

Arthritis Research & Therapy, 2018
Background The autoantibody profile of seropositive rheumatoid arthritis (RA) is very diverse and consists of various isotypes and antibodies to multiple post-translational modifications. It is yet unknown whether this varying breadth of the autoantibody
Emma C. de Moel, Veerle F. A. M. Derksen, Gerrie Stoeken, Leendert A. Trouw, Holger Bang, Robbert J. Goekoop, Irene Speyer, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude   +10 more
doaj   +1 more source

Determination of anti-ADAMTS-13 autoantibody titers in ELISA: Influence of ADAMTS-13 presentation and autoantibody detection

, 2021
BACKGROUND: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is caused by inhibitory and/or clearing anti-ADAMTS-13 (A Disintegrin and Metalloprotease with ThromboSpondin type 1 repeats, member 13) autoantibodies.
Mannik, Andres, Tellier, Edwige, Feys, Hendrik B., Kaplanski, Gilles, Vandenbulcke, Aline, Dekimpe, Charlotte, De Meyer, Simon F., Feys, Hendrik, Bonnez, Quintijn, Tersteeg, Claudia, Roose, Elien, Vanhoorelbeke, Karen, Kangro, Kadri, de Meyer, Simon   +13 more
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

The Autoantibodies against Tumor-Associated Antigens as Potential Blood-Based Biomarkers in Thyroid Neoplasia: Rationales, Opportunities and Challenges

Biomedicines, 2022
The Autoantibodies targeting Tumor-Associated Antigens (TAA-AAbs) emerge as a result of a variety of tumor-related immunogenic stimuli and may be regarded as the eyewitnesses to the anti-tumor immune response.
Pavel V. Belousov
doaj   +1 more source

Late-Onset Immunotherapy Toxicity and Delayed Autoantibody Changes: Checkpoint Inhibitor-Induced Raynaud's-Like Phenomenon

, 2020
The Oncologist published by Wiley Periodicals, Inc. on behalf of AlphaMed Press. Immune checkpoint inhibitor (ICI)-induced immune-related adverse events (irAEs) may affect almost any organ system and occur at any point during therapy.
Gerber, David E, Khan, Saad A, Lu, Rong, Li, Quan-Zhen, Khan, Shaheen, Park, Jason Y, Gloria-McCutchen, Yvonne, von Itzstein, Mitchell S, Karp, David R, Wakeland, Edward K, Xie, Yang, Bermas, Bonnie L, Saltarski, Jessica M, Fattah, Farjana J   +13 more
core   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review

Communications Medicine
Background Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation.
Jamie L. Felton, Maria J. Redondo, Richard A. Oram, Cate Speake, S. Alice Long, Suna Onengut-Gumuscu, Stephen S. Rich, Gabriela S. F. Monaco, Arianna Harris-Kawano, Dianna Perez, Zeb Saeed, Benjamin Hoag, Rashmi Jain, Carmella Evans-Molina, Linda A. DiMeglio, Heba M. Ismail, Dana Dabelea, Randi K. Johnson, Marzhan Urazbayeva, John M. Wentworth, Kurt J. Griffin, Emily K. Sims, On behalf of the ADA/EASD PMDI   +22 more
doaj   +1 more source

Mild Cognitive Impairment in Chronic Brain Injury Associated with Serum Anti-AP3B2 Autoantibodies: Report and Literature Review

Brain Sciences, 2021
Background: Chronic traumatic brain injury is a condition that predisposes the brain to activate B-cells and produce neural autoantibodies. Anti-adaptor protein 3, subunit B2 (AP3B2) autoantibodies have thus far been associated with diseases affecting ...
Niels Hansen, Dirk Fitzner, Winfried Stöcker, Jens Wiltfang, Claudia Bartels   +4 more
doaj   +1 more source