Results 11 to 20 of about 125,582 (266)

Increased immune complexes of hypocretin autoantibodies in narcolepsy. [PDF]

PLoS ONE, 2010
BACKGROUND: Hypocretin peptides participate in the regulation of sleep-wake cycle while deficiency in hypocretin signaling and loss of hypocretin neurons are causative for narcolepsy-cataplexy.
Aude Deloumeau, Sophie Bayard, Quentin Coquerel, Pierre Déchelotte, Christine Bole-Feysot, Bertrand Carlander, Valérie Cochen De Cock, Sergueï O Fetissov, Yves Dauvilliers   +8 more
doaj   +1 more source

Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto’s Thyroiditis

Journal of Immunology Research, 2023
T helper type 1 (Th1) and inflammatory cytokines play essential roles in early pregnancy and also in the pathogenesis of Hashimoto’s thyroiditis (HT).
Szabina Erdő-Bonyár, Diána Simon, Anna Bajnok, Jasper Nörenberg, Tímea Serény-Litvai, Ákos Várnagy, Kálmán Kovács, Eszter Hantosi, Emese Mezősi, Tímea Berki   +9 more
doaj   +1 more source

Malignancy-Associated Membranous Nephropathy with Positive Anti-PLA2R Autoantibodies: Coincidence or Connection

Case Reports in Nephrology and Dialysis, 2021
Membranous nephropathy (MN) is currently classified as either primary – often associated with positive anti-phospholipase-A2 receptor (PLA2R) autoantibodies – or as secondary – associated with malignancy, infection, medications, or autoimmune disease. We
Lyle W. Baker, Jaime Jimenez-Lopez, Xochiquetzal J. Geiger, Nabeel Aslam   +3 more
doaj   +1 more source

The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity

Virology Journal, 2023
Background Neutralizing anti-interferon (IFN)-γ autoantibodies are linked to adult-onset immunodeficiency and opportunistic infections. Methods To explore whether anti-IFN-γ autoantibodies are associated with disease severity of coronavirus disease 2019 (
Po-Ku Chen, Kai-Jieh Yeo, Shih-Hsin Chang, Tsai-Ling Liao, Chia-Hui Chou, Joung-Liang Lan, Ching-Kun Chang, Der-Yuan Chen   +7 more
doaj   +1 more source

The presence of autoantibodies is associated with improved overall survival in lung cancer patients

Frontiers in Oncology, 2023
ObjectiveAutoantibodies have been reported to be associated with cancers. As a biomarker, autoantibodies have been widely used in the early screening of lung cancer.
Keying Jing, Huijuan Zhao, Jun Cai, Lianlian Chen, Peiming Zheng, Libo Ouyang, Gang Li, Rong Wang   +7 more
doaj   +1 more source

Genetics and autoantibodies

Immunologic Research, 2013
Autoimmune diseases (ADs) are chronic conditions initiated by the loss of immunological tolerance to self-antigens. The pathogenic hypothesis comprises a complex interaction between genetic, environmental and hormonal factors that interact with an individual over time generating a dysregulation of the immune system leading to disease development ...
PERRICONE, CARLO, Nancy Agmon Levin, CECCARELLI, FULVIA, VALESINI, Guido, Juan Manuel Anaya, Yehuda Shoenfeld   +5 more
openaire   +3 more sources

Extrapancreatic autoantibody profiles in type I diabetes. [PDF]

PLoS ONE, 2012
Type I diabetes (T1D) is an autoimmune disease characterized by destruction of insulin-producing β-cells in the pancreas. Although several islet cell autoantigens are known, the breadth and spectrum of autoantibody targets has not been fully explored ...
Peter D Burbelo, Evan E Lebovitz, Kathleen E Bren, Ahmad Bayat, Scott Paviol, Janet M Wenzlau, Katherine J Barriga, Marian Rewers, David M Harlan, Michael J Iadarola   +9 more
doaj   +1 more source

Anticytokine Autoantibodies: Association with Infection and Immune Dysregulation

Antibodies, 2016
The association of autoantibodies to cytokines with immune deficiency, autoimmunity and/or immune dysregulation is increasingly being recognized. For example, autoantibodies to interferon gamma have been found to be associated with chronic, treatment ...
Vijaya Knight, Patricia A. Merkel, Michael D. O’Sullivan   +2 more
doaj   +1 more source

Autoantibody profiles in systemic sclerosis; a comparison of diagnostic tests

Autoimmunity, 2021
Objectives Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays.
Wynand Alkema, Hans Koenen, Brigit E. Kersten, Charlotte Kaffa, Jacqueline W. B. Dinnissen, Jan G. M. C. Damoiseaux, Irma Joosten, Sophie Driessen-Diks, Renate G. van der Molen, Madelon C. Vonk, Ruben L. Smeets   +10 more
doaj   +1 more source

Prevalence of Anti-neural Autoantibodies in a Psychiatric Patient Cohort-Paradigmatic Application of Criteria for Autoimmune-Based Psychiatric Syndromes

Frontiers in Psychiatry, 2022
BackgroundAnti-neural autoantibodies associated with psychiatric syndromes is an increasing phenomenon in psychiatry. Our investigation aimed to assess the frequency and type of neural autoantibodies associated with distinct psychiatric syndromes in a ...
Niels Hansen, Niels Hansen, Aaron Levin Juhl, Aaron Levin Juhl, Insa Maria Grenzer, Insa Maria Grenzer, Kristin Rentzsch, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Dirk Fitzner   +10 more
doaj   +1 more source