Results 11 to 20 of about 175,482 (253)

Angiotensin type-1 receptor and ACE2 autoantibodies in Parkinson´s disease

npj Parkinson's Disease, 2022
The role of autoimmunity in neurodegeneration has been increasingly suggested. The renin-angiotensin system (RAS) autoantibodies play a major role in several peripheral inflammatory processes.
Carmen M. Labandeira, Maria A. Pedrosa, Aloia Quijano, Rita Valenzuela, Pablo Garrido-Gil, Mariña Sanchez-Andrade, Juan A. Suarez-Quintanilla, Ana I. Rodriguez-Perez, Jose L. Labandeira-Garcia   +8 more
doaj   +1 more source

Autoantibodies against complement C1q in systemic lupus erythemathosus [PDF]

, 2008
Complement and C1q, the first component of the classical pathway of activation of the complement system, are considered to be involved in the pathogenesis of systemic lupus erythematosus (SLE), a systemic autoimmune disease.
Bigler, Cornelia
core   +1 more source

Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto’s Thyroiditis

Journal of Immunology Research, 2023
T helper type 1 (Th1) and inflammatory cytokines play essential roles in early pregnancy and also in the pathogenesis of Hashimoto’s thyroiditis (HT).
Szabina Erdő-Bonyár, Diána Simon, Anna Bajnok, Jasper Nörenberg, Tímea Serény-Litvai, Ákos Várnagy, Kálmán Kovács, Eszter Hantosi, Emese Mezősi, Tímea Berki   +9 more
doaj   +1 more source

Development of antigen-specific ELISA for circulating autoantibodies to extracellular matrix protein 1 in lichen sclerosus [PDF]

, 2004
Lichen sclerosus is a common, acquired chronic inflammatory skin disease of unknown etiology, although circulating autoantibodies to the glycoprotein extracellular matrix protein 1 (ECM1) have been detected in most patients’ sera.
Sallie M. Neill, Hughes, GJ, Ien Chan, Andrew P. South, Black, Martin M., Oyama, N, McGrath, John A., McGrath, J A, Kawakami, Y, Fenella Wojnarowska, John A. McGrath, Mepani, K, Balbir S. Bhogal, South, AP, South, A P, Chan, Ien, Kaneko, F, Kawakami, Yoshio, Chan, I, Kirti Mepani, South, Andrew P., Bhogal, BS, Neill, Sallie M., Oyama, Noritaka, Bhogal, B S, Noritaka Oyama, Bhogal, Balbir S., David D’Cruz, Neill, SM, Mepani, Kirti, McGrath, JA, Fumio Kaneko, Kaneko, Fumio, D'Cruz, David, Hughes, G J, D'Cruz, D, Martin M. Black, Graham J. Hughes, Neill, S M, Hughes, Graham J., Yoshio Kawakami, Wojnarowska, F, Black, MM, Black, M M, Wojnarowska, Fenella   +44 more
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Anti-melanocortin-4 receptor autoantibodies in obesity [PDF]

, 2009
Background: The melanocortin-4 receptor (MC4R) is part of an important pathway regulating energy balance. Here we report the existence of autoantibodies (autoAbs) against the MC4R in sera of obese patients.
Kessler, L., Muller, Sylviane, Lecourt, Anne-Catherine, Bekel, Akkiz, Bekel, A., Zipfel, G., Peter, J. C., Kessler, Laurence, Eftekhari, Pierre, Eftekhari, P., Zipfel, Géraldine, Hofbauer, Karl G, Breidert, M., Breidert, Matthias, Lecourt, A. C., Muller, S., Nesslinger, Maya, Hofbauer, K. G., Nesslinger, M., Peter, Jean-Christophe   +19 more
core   +1 more source

Increased immune complexes of hypocretin autoantibodies in narcolepsy. [PDF]

PLoS ONE, 2010
BACKGROUND: Hypocretin peptides participate in the regulation of sleep-wake cycle while deficiency in hypocretin signaling and loss of hypocretin neurons are causative for narcolepsy-cataplexy.
Aude Deloumeau, Sophie Bayard, Quentin Coquerel, Pierre Déchelotte, Christine Bole-Feysot, Bertrand Carlander, Valérie Cochen De Cock, Sergueï O Fetissov, Yves Dauvilliers   +8 more
doaj   +1 more source

Malignancy-Associated Membranous Nephropathy with Positive Anti-PLA2R Autoantibodies: Coincidence or Connection

Case Reports in Nephrology and Dialysis, 2021
Membranous nephropathy (MN) is currently classified as either primary – often associated with positive anti-phospholipase-A2 receptor (PLA2R) autoantibodies – or as secondary – associated with malignancy, infection, medications, or autoimmune disease. We
Lyle W. Baker, Jaime Jimenez-Lopez, Xochiquetzal J. Geiger, Nabeel Aslam   +3 more
doaj   +1 more source

Recombinant human preproinsulin expression, purification and reaction with insulin autoantibodies in sera from patients with insulin-dependent diabetes mellitus [PDF]

, 1993
A novel prokaryotic expression vector pGEX-6T was designed for high-level expression of recombinant fusion protein with a histidine-hexapeptide and glutathione-S-transferase at its N-terminus and the recombinant human preproinsulin at its C-terminus ...
Seißler, Jochen, Mauch, Ludwig, Walter, Michael, Northemann, Wolfgang, Berg, Heike   +4 more
core   +1 more source

The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity

Virology Journal, 2023
Background Neutralizing anti-interferon (IFN)-γ autoantibodies are linked to adult-onset immunodeficiency and opportunistic infections. Methods To explore whether anti-IFN-γ autoantibodies are associated with disease severity of coronavirus disease 2019 (
Po-Ku Chen, Kai-Jieh Yeo, Shih-Hsin Chang, Tsai-Ling Liao, Chia-Hui Chou, Joung-Liang Lan, Ching-Kun Chang, Der-Yuan Chen   +7 more
doaj   +1 more source

The presence of autoantibodies is associated with improved overall survival in lung cancer patients

Frontiers in Oncology, 2023
ObjectiveAutoantibodies have been reported to be associated with cancers. As a biomarker, autoantibodies have been widely used in the early screening of lung cancer.
Keying Jing, Huijuan Zhao, Jun Cai, Lianlian Chen, Peiming Zheng, Libo Ouyang, Gang Li, Rong Wang   +7 more
doaj   +1 more source