Results 11 to 20 of about 221,867 (307)

Natural Anti-NMDAR1 autoantibodies associate with slowed decline of cognitive functions in Alzheimer’s diseases [PDF]

Translational Psychiatry
Low titers of blood circulating natural anti-NMDAR1 autoantibodies were reported in ~10% of the general human population. Their potential effects on NMDAR functions in the brain, however, remain unknown.
Xianjin Zhou
doaj   +2 more sources

A novel platform for isotype-specific testing of autoantibodies. [PDF]

PLoS ONE, 2019
The objective of this study was to test if a novel platform could be used for isotype-specific autoantibody testing in humans. Further, we evaluated if testing with this novel platform enables earlier detection of insulin autoantibodies in individuals ...
Kaylene L Carter, Anckia Treurnicht, Kara L Davis, Rajiv B Kumar, Brian J Feldman   +4 more
doaj   +3 more sources

Associations of body weight and COVID-19 with autoimmunity in pediatric new-onset type 1 diabetes: results from the prospective DPV registry [PDF]

BMJ Open Diabetes Research & Care
Introduction This study analyzed the effects of the COVID-19 pandemic and body weight on islet and endocrine autoimmunity in children with type 1 diabetes (T1D).Research design and methods Data from 11 973 children and adolescents aged 0.5 to <18 ...
Katharina Warncke, Reinhard Holl, Claudia Boettcher, Katrin Nagl, Thekla von dem Berge, Beate Karges, Simone Von Sengbusch, Alena Welters, Monika Flury, Diyah Nahdiyati, Clemens Kamrath   +10 more
doaj   +2 more sources

VEGF controls microglial phagocytic response to amyloid-β

Frontiers in Cellular Neuroscience, 2023
Microglial cells are well known to be implicated in the pathogenesis of Alzheimer’s disease (AD), due to the impaired clearance of amyloid-β (Aβ) protein.
Priscille de Gea, Sarah Benkeder, Pauline Bouvet, Mélanie Aimard, Naura Chounlamountri, Jérôme Honnorat, Jérôme Honnorat, Le Duy Do, Le Duy Do, Claire Meissirel   +9 more
doaj   +1 more source

Conformation-stabilizing ELISA and cell-based assays reveal patient subgroups targeting three different epitopes of AGO1 antibodies

Frontiers in Immunology, 2022
Autoantibodies (Abs) are biomarkers for many disease conditions and are increasingly used to facilitate diagnosis and treatment decisions. To guarantee high sensitivity and specificity, the choice of their detection method is crucial.
Christian P. Moritz, Christian P. Moritz, Christian P. Moritz, Le-Duy Do, Le-Duy Do, Yannick Tholance, Yannick Tholance, Yannick Tholance, Pierre-Baptiste Vallayer, Véronique Rogemond, Véronique Rogemond, Bastien Joubert, Bastien Joubert, Karine Ferraud, Karine Ferraud, Coralie La Marca, Coralie La Marca, Jean-Philippe Camdessanché, Jean-Philippe Camdessanché, Jean-Philippe Camdessanché, Jean-Philippe Camdessanché, Jean-Philippe Camdessanché, Jérôme Honnorat, Jérôme Honnorat, Jérôme Honnorat, Jean-Christophe Antoine, Jean-Christophe Antoine, Jean-Christophe Antoine, Jean-Christophe Antoine, Jean-Christophe Antoine   +29 more
doaj   +1 more source

Autoantibodies against complement factor B in rheumatoid arthritis

Frontiers in Immunology, 2023
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder affecting the joints. Many patients carry anti-citrullinated protein autoantibodies (ACPA).
Alexandra T. Matola, Alexandra T. Matola, Angéla Fülöp, Bernadette Rojkovich, György Nagy, György Nagy, György Nagy, György Nagy, Gabriella Sármay, Mihály Józsi, Mihály Józsi, Barbara Uzonyi, Barbara Uzonyi   +12 more
doaj   +1 more source

Autoantibodies predict type 1 diabetes after gestational diabetes – a 23-year cohort study

Frontiers in Endocrinology, 2023
ObjectiveTo study the predictive value of autoantibodies for type 1 (T1DM) and type 2 (T2DM) diabetes morbidity after gestational diabetes (GDM) in a 23-year follow-up study.DesignProspective population-based cohort study.MethodsWe studied 391 women with
Kaisu Luiro, Anna-Maaria Auvinen, Anna-Maaria Auvinen, Juha Auvinen, Juha Auvinen, Jari Jokelainen, Ilkka Järvelä, Mikael Knip, Mikael Knip, Mikael Knip, Juha S. Tapanainen, Juha S. Tapanainen, Juha S. Tapanainen, Juha S. Tapanainen   +13 more
doaj   +1 more source

The significance of preclinical anti-BP180 autoantibodies

Frontiers in Immunology, 2022
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease. Although the pathomechanism of BP onset has yet to be elucidated in detail, BP autoantibodies targeting two hemidesmosomal components, BP180 and BP230, are known to ...
Yosuke Mai, Kentaro Izumi, Shoko Mai, Hideyuki Ujiie   +3 more
doaj   +1 more source

Myositis autoantibodies [PDF]

Current Opinion in Rheumatology, 2012
To review recent advances in our understanding of autoantibodies associated with dermatomyositis and the autoimmune necrotizing myopathies.Autoantibodies preferentially associated with dermatomyositis include those recognizing Mi-2, MDA5, TIF1γ, and NXP-2. Each of these is associated with a distinct clinical phenotype.
Livia, Casciola-Rosen, Andrew L, Mammen
openaire   +2 more sources

Immunoglobulin E and G autoantibodies against eosinophil proteins in children and adults with asthma and healthy subjects

World Allergy Organization Journal, 2023
Background: Autoimmune IgG response has been described in the pathogenesis of asthma in adults, but IgE autoimmunity has been little explored. Considering high levels of blood eosinophils and immunoglobulin E in asthmatic patients, the possibility of IgE
Jorge Sánchez, MD, MSc, EAC, PhD, Andres Sánchez Biol, MSc, Marlon Múnera Biol, PhD, Elizabeth García, MD, EAC, Juan-Felipe López, MD, MSc   +4 more
doaj   +1 more source