Results 41 to 50 of about 159,852 (315)

Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II [PDF]

, 1994
By using an immunoprecipitation assay, we analysed reactivity of autoantibodies to human recombinant GAD65 and GAD67 in sera from patients with autoimmune polyendocrine syndrome Type II (APS II) with and without Type 1 (insulin-dependent) diabetes ...
Seißler, Jochen, Bieg, Sabine, Yassin, Nadja, Mauch, Ludwig, Böhm, Bernhard Otto, Northemann, Wolfgang, Scherbaum, Werner A.   +6 more
core   +1 more source

Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer

Arthritis Research & Therapy, 2018
Background The close temporal association between onset of some connective tissue diseases and cancer suggests a paraneoplastic association.
Zoe E. Betteridge, Lynsey Priest, Robert G. Cooper, Neil J. McHugh, Fiona Blackhall, Janine A. Lamb   +5 more
doaj   +1 more source

Psychopathology of psychiatric patients presenting autoantibodies against neuroglial antigens

Frontiers in Psychiatry, 2022
BackgroundAutoantibody-mediated psychiatric disorder is often difficult to diagnose as the clinical features of psychiatric disorder associated with neural autoantibodies are often similar.
Insa Maria Grenzer, Insa Maria Grenzer, Aaron Levin Juhl, Aaron Levin Juhl, Bianca Teegen, Dirk Fitzner, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Niels Hansen, Niels Hansen   +10 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Autoantibodies Against Factor B and Factor H Without Pathogenic Effects in a Patient with Immune Complex-Mediated Membranoproliferative Glomerulonephritis

Biomedicines
Background: Membranoproliferative glomerulonephritis (MPGN) is an umbrella term for chronic disorders affecting the glomeruli. MPGN is often accompanied by the presence of autoantibodies against complement components.
Alexandra T. Matola, Dorottya Csuka, Ágnes Szilágyi, Michael Rudnicki, Zoltán Prohászka, Mihály Józsi, Barbara Uzonyi   +6 more
doaj   +1 more source

Autoantibodies Against the Complement Regulator Factor H in the Serum of Patients With Neuromyelitis Optica Spectrum Disorder

Frontiers in Immunology, 2021
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disease of the central nervous system (CNS), characterized by pathogenic, complement-activating autoantibodies against the main water channel in the CNS, aquaporin 4 (AQP4 ...
Barbara Uzonyi, Barbara Uzonyi, Zsóka Szabó, Eszter Trojnár, Eszter Trojnár, Satu Hyvärinen, Katalin Uray, Helle H. Nielsen, Anna Erdei, Anna Erdei, T. Sakari Jokiranta, Zoltán Prohászka, Zoltán Prohászka, Zsolt Illes, Zsolt Illes, Mihály Józsi, Mihály Józsi, Mihály Józsi   +17 more
doaj   +1 more source

Deciphering the Contribution of BP230 Autoantibodies in Bullous Pemphigoid [PDF]

, 2022
Bullous pemphigoid (BP) is a subepidermal autoimmune blistering disease predominantly affecting elderly patients and carries significant morbidity and mortality.
Luca Borradori, Borradori, Luca, Kyle T. Amber, Cole, Connor, Amber, Kyle T, Amber, Kyle T., Connor Cole   +6 more
core   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Novel enzyme-linked immunosorbent assay for bivalent ZnT8 autoantibodies

, 2014
Autoantibodies to zinc transporter 8 (ZnT8A) are a powerful diagnostic or predictive marker in type 1 diabetes. However, the widely used current ZnT8A radioligand binding assay (RBA) has proved to be difficult for many laboratories to implement.
Miwa, Masaki, Tanaka, Megumi, Kawakami, Atsushi, Abiru, Norio, Kawasaki, Eiji   +4 more
core   +1 more source

Gad65 is recognized by t-cells, but not by antibodies from nod-mice [PDF]

, 1994
Since the 64kDa-protein glutamic acid decarboxylase (GAD) is one of the major autoantigens in T-cell mediated Type 1 diabetes, its relevance as a T-cell antigen needs to be clarified. After isolation of splenic T-cells from non-obese diabetic (NOD) mice,
Seißler, Jochen, Bieg, Sabine, Herberg, Lieselotte, Northemann, Wolfgang, Scherbaum, Werner A.   +4 more
core   +1 more source