Results 21 to 30 of about 221,867 (307)

Affinity purification of serum-derived anti-IA-2 autoantibodies in type 1 diabetes using a novel MBP-IA-2 fusion protein

Biochemistry and Biophysics Reports, 2023
Autoantibodies targeting epitopes contained within the intracellular domain (IC) of the protein phosphatase-like islet antigen 2 (IA-2) are a common marker of autoimmune type 1 diabetes (T1D), however the isolation of genuine, serum derived anti-IA-2 ...
Thilini Mendis, Barbora Filipova, Jing Jing Wang, Massimo Pietropaolo, Michael W. Jackson   +4 more
doaj   +1 more source

Angiotensin type-1 receptor and ACE2 autoantibodies in Parkinson´s disease

npj Parkinson's Disease, 2022
The role of autoimmunity in neurodegeneration has been increasingly suggested. The renin-angiotensin system (RAS) autoantibodies play a major role in several peripheral inflammatory processes.
Carmen M. Labandeira, Maria A. Pedrosa, Aloia Quijano, Rita Valenzuela, Pablo Garrido-Gil, Mariña Sanchez-Andrade, Juan A. Suarez-Quintanilla, Ana I. Rodriguez-Perez, Jose L. Labandeira-Garcia   +8 more
doaj   +1 more source

Lymphocytotoxic Autoantibodies [PDF]

, 2007
Anti-lymphocytic antibodies (anti-LCA) are detected in patients with systemic lupus erythematosus (SLE) with a prevalence ranging from 60–90%. LCA detection is associated with nephritis and neurologic disorders in these patients, and high rates of LCA occur during phases of active SLE.
Renaudineau, Yves, Pers, Jacques-Olivier, Youinou, Pierre   +2 more
openaire   +2 more sources

Malignancy-Associated Membranous Nephropathy with Positive Anti-PLA2R Autoantibodies: Coincidence or Connection

Case Reports in Nephrology and Dialysis, 2021
Membranous nephropathy (MN) is currently classified as either primary – often associated with positive anti-phospholipase-A2 receptor (PLA2R) autoantibodies – or as secondary – associated with malignancy, infection, medications, or autoimmune disease. We
Lyle W. Baker, Jaime Jimenez-Lopez, Xochiquetzal J. Geiger, Nabeel Aslam   +3 more
doaj   +1 more source

Increased immune complexes of hypocretin autoantibodies in narcolepsy. [PDF]

PLoS ONE, 2010
BACKGROUND: Hypocretin peptides participate in the regulation of sleep-wake cycle while deficiency in hypocretin signaling and loss of hypocretin neurons are causative for narcolepsy-cataplexy.
Aude Deloumeau, Sophie Bayard, Quentin Coquerel, Pierre Déchelotte, Christine Bole-Feysot, Bertrand Carlander, Valérie Cochen De Cock, Sergueï O Fetissov, Yves Dauvilliers   +8 more
doaj   +1 more source

Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus. [PDF]

, 2016
High titer, class-switched autoantibodies are a hallmark of systemic lupus erythematosus (SLE). Dysregulation of the interferon (IFN) pathway is observed in individuals with active SLE, although the association of specific autoantibodies with chemokine ...
Baechler, Emily C, Balboni, Imelda M, Diep, Vivian K, Haddon, D James, Hall, Drew A, Lee, Jung-Rok, Petri, Michelle, Price, Jordan V, Utz, Paul J, Wand, Hannah E, Wang, Shan X   +10 more
core   +2 more sources

Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto’s Thyroiditis

Journal of Immunology Research, 2023
T helper type 1 (Th1) and inflammatory cytokines play essential roles in early pregnancy and also in the pathogenesis of Hashimoto’s thyroiditis (HT).
Szabina Erdő-Bonyár, Diána Simon, Anna Bajnok, Jasper Nörenberg, Tímea Serény-Litvai, Ákos Várnagy, Kálmán Kovács, Eszter Hantosi, Emese Mezősi, Tímea Berki   +9 more
doaj   +1 more source

The presence of autoantibodies is associated with improved overall survival in lung cancer patients

Frontiers in Oncology, 2023
ObjectiveAutoantibodies have been reported to be associated with cancers. As a biomarker, autoantibodies have been widely used in the early screening of lung cancer.
Keying Jing, Huijuan Zhao, Jun Cai, Lianlian Chen, Peiming Zheng, Libo Ouyang, Gang Li, Rong Wang   +7 more
doaj   +1 more source

Clinical relevance of silent red blood cell autoantibodies. [PDF]

, 2017
.
Alessandri, C, Caputo, Md, Colafigli, G, Coluzzi, S, De Propris, Ms, Foà, R, Giovannetti, G, Girelli, G, Guarini, Ar, Mauro, Fr, Pepe, S, Porrazzo, M, Riemma, C, Trastulli, F, Valesini, G   +14 more
core   +1 more source

The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity

Virology Journal, 2023
Background Neutralizing anti-interferon (IFN)-γ autoantibodies are linked to adult-onset immunodeficiency and opportunistic infections. Methods To explore whether anti-IFN-γ autoantibodies are associated with disease severity of coronavirus disease 2019 (
Po-Ku Chen, Kai-Jieh Yeo, Shih-Hsin Chang, Tsai-Ling Liao, Chia-Hui Chou, Joung-Liang Lan, Ching-Kun Chang, Der-Yuan Chen   +7 more
doaj   +1 more source