Results 21 to 30 of about 175,482 (253)

Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more [PDF]

, 2012
B cells and antibodies constitute an important element in different inflammatory diseases of the central nervous system (CNS). Autoantibodies can serve as a biomarker to identify disease subgroups and may in addition contribute to the pathogenic process.
Mayer, Marie Cathrin, Meinl, Edgar, Marie Cathrin Mayer, Edgar Meinl, Meinl, E., Mayer, M.   +5 more
core   +1 more source

Insulin autoantibodies as determined by competitive radiobinding assay are positively correlated with impaired beta-cell function — The Ulm-Frankfurt population study [PDF]

, 1991
Out of a random population of 4208 non-diabetic pupils without a family history of Type I diabetes 44 (1.05%) individuals had islet cell antibody (ICA) levels greater or equal to 5 Juvenile Diabetes Foundation (JDF) units. 39 of these ICA-positives could
N. Yassin I, B. O. Boehm Z, Abteilung Innere Medizin I, Seißler, Jochen, Heinze, Eberhard, Pfeiffer, Ernst Friedrich, E. Heinze, Böhm, Bernhard Otto, Yassin, Nuha, J. Seigler, Glück, Michael, E. F. Pfeiffer, M. Glfick, W. A. Scherbaum, Scherbaum, Werner A.   +14 more
core   +1 more source

Novel enzyme-linked immunosorbent assay for bivalent ZnT8 autoantibodies [PDF]

, 2014
Autoantibodies to zinc transporter 8 (ZnT8A) are a powerful diagnostic or predictive marker in type 1 diabetes. However, the widely used current ZnT8A radioligand binding assay (RBA) has proved to be difficult for many laboratories to implement.
Miwa, Masaki, Tanaka, Megumi, Kawakami, Atsushi, Abiru, Norio, Kawasaki, Eiji   +4 more
core   +1 more source

Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits [PDF]

, 2008
Background: In celiac disease gluten, the disease-inducing toxic component in wheat, induces the secretion of autoantibodies which are targeted against transglutaminase 2 (TG2). These autoantibodies are produced in the small-intestinal mucosa, where they
Markku Maki, Korponay-Szabó, Ilma Rita, Korponay-Szabo Ilma R, Lohi, Olli, Ilma R Korponay-Szabo, Katri Haimila, Stenman, Satumarja M., Olli Lohi, Partanen, Jukka, Herbert Wieser, Maki, Markku, Mäki Markku, Lindfors, Katri, Haimila Katri, Paivi Saavalainen, Saavalainen Päivi, Saavalainen, Paivi, Lohi Olli, Stenman, Satumarja M, Partanen Jukka, Kaukinen, Katri, Satumarja M Stenman, Haimila, Katri, Stenman Satumarja M, Wieser Herbert, Katri Kaukinen, Wieser, Herbert, Kaukinen Katri, Korponay-Szabó, Ilma, Katri Lindfors, Jukka Partanen, Lindfors Katri   +31 more
core   +1 more source

Autoantibodies to insulin, insulinoma-associated antigen-2, and zinc transporter 8 improve the prediction of early insulin requirement in adult-onset autoimmune diabetes [PDF]

, 2010
Objective: The aim of this study was to indentify the predictive marker for early insulin requirement in adult-onset autoimmune diabetes in the Japanese populations.Design/Patients: We analyzed insulin autoantibodies (IAA), IA-2 autoantibodies (IA-2icA)
Eguchi, Katsumi, Yamasaki, Hironori, Kobayashi, Masakazu, Satoh, Tsuyoshi, Kuwahara, Hironaga, Kuriya, Genpei, Abiru, Norio, Kawasaki, Eiji, Nakamura, Kan   +8 more
core   +1 more source

Extrapancreatic autoantibody profiles in type I diabetes. [PDF]

PLoS ONE, 2012
Type I diabetes (T1D) is an autoimmune disease characterized by destruction of insulin-producing β-cells in the pancreas. Although several islet cell autoantigens are known, the breadth and spectrum of autoantibody targets has not been fully explored ...
Peter D Burbelo, Evan E Lebovitz, Kathleen E Bren, Ahmad Bayat, Scott Paviol, Janet M Wenzlau, Katherine J Barriga, Marian Rewers, David M Harlan, Michael J Iadarola   +9 more
doaj   +1 more source

Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: Increased prevalence of ASCA and pANCA [PDF]

, 2004
Aims: An association between inflammatory bowel disease (IBD) and spondyloarthropathies (SpA) has repeatedly been reported. The aim of the present study was to investigate whether serologic markers of IBD, e. g.
Folwaczny, Christian, Kellner, H., J. Glas, Marker-Hermann, E., R. Gruber, Brumberger, V., V. Brumberger, Glas, J., Gruber, R., H. Kellner, C. Folwaczny, Török, H.-P., E. Märker-Hermann, C. Strasser, Strasser, C., H.-P. Török   +15 more
core   +1 more source

Anticytokine Autoantibodies: Association with Infection and Immune Dysregulation

Antibodies, 2016
The association of autoantibodies to cytokines with immune deficiency, autoimmunity and/or immune dysregulation is increasingly being recognized. For example, autoantibodies to interferon gamma have been found to be associated with chronic, treatment ...
Vijaya Knight, Patricia A. Merkel, Michael D. O’Sullivan   +2 more
doaj   +1 more source

Autoantibody profiles in systemic sclerosis; a comparison of diagnostic tests

Autoimmunity, 2021
Objectives Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays.
Wynand Alkema, Hans Koenen, Brigit E. Kersten, Charlotte Kaffa, Jacqueline W. B. Dinnissen, Jan G. M. C. Damoiseaux, Irma Joosten, Sophie Driessen-Diks, Renate G. van der Molen, Madelon C. Vonk, Ruben L. Smeets   +10 more
doaj   +1 more source

Storage-induced changes in erythrocyte membrane proteins promote recognition by autoantibodies [PDF]

, 2012
Contains fulltext : 109602.pdf (Publisher’s version ) (Open Access)Physiological erythrocyte removal is associated with a selective increase in expression of neoantigens on erythrocytes and their vesicles, and subsequent autologous ...
Dinkla, S., Věra M J Novotný, Novotný Věra M. J., Věra M. J. Novotný (144892), Dinkla, S, Joosten, I, Novotný, VM, Sip Dinkla, Giel J C G M Bosman, Bosman, G.J.C.G.M., Irma Joosten, Dinkla Sip, Giel J. C. G. M. Bosman (144896), Novotny, V.M.J., Joosten, I., Joosten Irma, Bosman, GJ, Irma Joosten (27492), Bosman Giel J. C. G. M., Sip Dinkla (144890)   +19 more
core   +3 more sources