Results 21 to 30 of about 31,308 (159)

Causal relationship between gut microbiota and myasthenia gravis: a bidirectional mendelian randomization study

Cell & Bioscience, 2023
Background Observational studies have demonstrated an association between gut microbiota and myasthenia gravis; however, the causal relationship between the two still lacks clarity.
Tengfei Su, Xiang Yin, Jiaxin Ren, Yue Lang, Weiguanliu Zhang, Li Cui   +5 more
doaj   +1 more source

Efgartigimod Combined with Glucocorticoids in the Treatment of Severe Generalized Myasthenia Gravis: A Single-Center, Retrospective Cohort Study

Neurology and Therapy
Introduction High-dose intravenous methylprednisolone (IVMP) is effective in treating generalized myasthenia gravis (gMG), but early-stage transient aggravation and MG crisis can occur.
Shanshan Gu, Yongzhao Li, Huimin Dong, Hongxia Yang, Mei Ma, Mengna Li, Congya Yan, Pei Jia, Yaxuan Wang, Guoyan Qi   +9 more
doaj   +1 more source

Identification of potential prognostic biomarkers of thymoma with myasthenia gravis based on serum proteomics

Frontiers in Immunology
BackgroundThymoma is often associated with myasthenia gravis (MG), and the resection of thymoma improves myasthenic symptoms in patients with thymoma and MG (TMG), but some patients still have no relief.
Xiaoting Lin, Xiaoting Lin, Xiaoting Lin, Xiaoting Lin, Peng Liu, Peng Liu, Peng Liu, Peng Liu, Guoyan Qi, Guoyan Qi, Guoyan Qi, Guoyan Qi   +11 more
doaj   +1 more source

Concentric Needle Jitter in 97 Myasthenia Gravis Patients

Frontiers in Neurology, 2020
Objectives: To estimate the jitter parameters (single-fiber electromyography) in myasthenia gravis patients mostly by electrical activation in Frontalis, Orbicularis Oculi, and Extensor Digitorum muscles using a concentric needle electrode.Methods ...
João Aris Kouyoumdjian, Gabriel Pina Paiva, Erik Stålberg   +2 more
doaj   +1 more source

Methylprednisolone pulse versus docetaxel in recurrent thymoma with myasthenia gravis

Frontiers in Neurology
IntroductionThis study aims to compare the effectiveness and safety of methylprednisolone pulse versus docetaxel in treating recurrent thymoma with myasthenia gravis (MG).MethodsWe conducted a single-center, open-label, retrospective study that included ...
Hongxia Yang, Hongxia Yang, Yaxuan Wang, Zulin Pan, Ze Liu, Ze Liu, Biqi Cheng, Guoyan Qi, Guoyan Qi, Guoyan Qi   +9 more
doaj   +1 more source

A nurse-led nomogram for predicting the risk of myasthenic crisis in patients with myasthenia gravis and bulbar weakness

BMC Neurology
Background The present study aimed to develop and validate a nurse-led clinical prediction model for assessing the risk of myasthenic crisis (MC) in myasthenia gravis (MG) patients with bulbar weakness.
Huimin Dong, Mengna Li, Mei Ma, Guoyan Qi   +3 more
doaj   +1 more source

Clinical predictors for the prognosis of myasthenia gravis

BMC Neurology, 2017
Background Clinical predictors for myasthenia gravis relapse and ocular myasthenia gravis secondary generalization during the first two years after disease onset remain incompletely identified.
Lili Wang, Yun Zhang, Maolin He
doaj   +1 more source

Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study. [PDF]

PLoS ONE, 2014
The mechanisms that underlie the development and maintenance of autoimmunity in myasthenia gravis are poorly understood. In this investigation, we evaluate the role of survivin, a member of the inhibitor of apoptosis protein family, in humans and in two ...
Linda L Kusner, Michael J Ciesielski, Alexander Marx, Henry J Kaminski, Robert A Fenstermaker   +4 more
doaj   +1 more source

Myasthenia gravis

The Lancet, 2001
Myasthenia gravis is an autoimmune disorder mainly caused by antibodies to the muscle acetylcholine receptors (AChRs) at the neuromuscular junction. Loss of these receptors leads to a defect in neuromuscular transmission with muscle weakness and fatigue.
Vincent, A, Palace, J, Hilton-Jones, D
openaire   +2 more sources

Features of depression development in myasthenia gravis.

Medičnì Perspektivi, 2020
The relative risk of developing depression in myasthenia gravis is 2.14 times higher than in the general population. The features of depression in myasthenia patients remain poorly understood and need to be clarified.
O. I. Kalbus, S. O. Makarov, N. P. Shastun, O. V. Somilo, Yu. V. Bukreyeva   +4 more
doaj   +1 more source