Results 1 to 10 of about 1,344,517 (267)
Determining cut-points for Alzheimer's disease biomarkers: statistical issues, methods and challenges. [PDF]
, 2012 New proposed criteria for the clinical diagnosis of Alzheimer's disease increasingly incorporate biomarkers, most of which are normally measured on a continuous scale. Operationalizing such criteria thus requires continuous biomarkers to be dichotomized, Skillbäck, Tobias,, Blennow, Kaj,, Bartlett, Jonathan W, Zetterberg, Henrik,, Blennow, Kaj, Zetterberg, Henrik, Frost, Chris, Mattsson, Niklas, Skillbäck, Tobias, Schott, Jonathan M, Mattsson, Niklas, +10 morecore +1 more sourceProteomic candidate biomarkers of drug-induced nephrotoxicity in the rat [PDF]
, 2012 Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were ...Hanig, J., Mischak, H., Harald Mischak (103627), Rouse Rodney, Mullen, W., Metzger, J., William Mullen (103621), Rodney Rouse, William Mullen, Jochen Metzger, Jochen Metzger (171762), Hanig Joseph, Siwy, J., Joseph Hanig, Justyna Siwy (103595), Mullen William, Harald Mischak, Rouse, R., Justyna Siwy, Rodney Rouse (171753), Metzger Jochen, Joseph Hanig (82484), Siwy Justyna, Mischak Harald +23 morecore +1 more sourceThe use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey [PDF]
, 2014 We investigated the use of Alzheimer's disease (AD) biomarkers in European Alzheimer's Disease Consortium centers and assessed their perceived usefulness for the etiologic diagnosis of mild cognitive impairment (MCI).Erikdotter, M, Samantha Galluzzi, Peters, Oliver, Galluzi, S, Andreas Monsch, Jones, Roy W, Mehrabian, S., Zekry, Dina, Wilcock, G, Sarazin, M., Sánchez-Castellano, Carmen, Martinez-Lage, P, Kehoe, P.G., Wallin, Åsa,, Hallikainen, M., Monsch, A, Santana, I, Felician, O, Frolich, L, Rikkert, M.O., Isabel Santana, Wilcock, Gordon, Jean‐Marc Orgogozo, Flavio Nobili, Mecocci, P, Hausner, Lucrezia, Roy W. Jones, Jessen, F., Heuser, I., Isabell Heuser, Eric Salmon, David Wilkinson, Froelich, L., Félician, Olivier, Maria Eriksdotter, Ceccaldi, M, Sarazin, M, Olde Rikkert, Marcel, de Mendonca, A., Aguera, E., Galluzzi, Samantha, Felician, O., Pasquier, F., Patrick Gavin Kehoe, Wolf, H, Nordberg, Agneta, Shima Mehrabian, Latchezar Traykov, Frolich, L., Mira Didic, Dartigues, Jean François, Hasselbalch, S.G., Aguera, Eduardo, Alberto Lleo, Sarazin, Marie, Martina Bocchetta, Brian Lawlor, Wallin, Åsa K, Dartigues, J.F., Monsch, A., Magda Tsolaki, Wilkinson, D., Giovanni B. Frisoni, Sanchez-Castellano, C, Yener, Goersev, NOBILI, FLAVIO MARIANO, Nobili, Flavio, Eriksdotter, Maria, Bernabei, R, Hallikainen, M, Gertz, H.J., Frisoni, Giovanni B., Lleo, A, Eduardo Aguera, Hallikainen, Merja, Roberto Bernabei, Alexandre de Mendonça, Gordon Wilcock, Visser, Pieter Jelle, Bullock, R., Frisoni, G.B., Bernabei, Roberto, Jones, Roy W., Alexander Kurz, Sanchez-Castellano, C., Wallin, Åsa, Bochetta, M, Bullock, R, Martinez-Lage, P., Patrizia Mecocci, Frank Jessen, Lleo, Alberto, Ceccaldi, M., Pablo Martinez‐Lage, Nobili, F., Florence Pasquier, Salmon, E., Eriksdotter, M., Lawlor, B., de Mendonça, Alexandre, Dartigues, Jean-François, Jessen, F, Pasquier, Florence, Marie Sarazin, Lucrezia Hausner, Monsch, Andreas, Rikkert, Marcel Olde, Dina Zekry, Carmen Sánchez‐Castellano, Pasquier, F, Traykov, L., Didic, M., Tsolaki, M, Nordberg, A., Pieter Jelle Visser, Kehoe, Patrick Gavin, Orgogozo, J.M., Froelich, Lutz, Kurz, A, Nobili, F, Bocchetta, M., Lund University., Martinez-Lage, Pablo, Agneta Nordberg, Åsa K. Wallin, Frisoni, G. B., Hasselbalch, Steen G, Zekry, D., Wilkinson, D, Gertz, Hermann Josef, Ceccaldi, Mathieu, Galluzzi, S., Santana, Isabel, Wilcock, G., Lleo, A., Mehrabian, S, Kurz, A., Heuser, Isabell, Gertz, Hermann-Josef, Kurz, Alexander, Wilkinson, David, Jean‐François Dartigues, Oliver Peters, Hausner, L, Mecocci, Patrizia, Peters, O., Roger Bullock, Lutz Frölich, Frisoni, Giovanni B, Merja Hallikainen, Orgogozo, Jean Marc, Jones, R.W., Henrike Wolf, Nordberg, A, Mecocci, P., Olde Rikkert, M, Olivier Félician, Wolf, Henrike, Bullock, Roger, Yener, G, Wallin, Åsa K., Peters, O, Yener, Görsev, Wolf, H., Didic, Mira, Mathieu Ceccaldi, Hausner, L., de Mendonca, A, Lawlor, Brian, Jessen, Frank, Orgogozo, Jean-Marc, Bernabei, R., Marcel Olde Rikkert, Mendonca, A. de, Heuser, I, Mehrabian, Shima, Salmon, Eric, Traykov, L, Visser, P.J., Bocchetta, Martina, Aguera, E, Martinez Lage, Pablo, Frölich, Lutz, Hermann‐Josef Gertz, Steen G. Hasselbalch, Didic, M, Tsolaki, M., Tsolaki, Magda, Hasselbalch, Steen G., Santana, I., Hasselbach, S.G., Lawlor, B, Olde Rikkert, M.G.M., Yener, G., Görsev Yener, Wallin, A.K., Traykov, Latchezar, Sänchez Castellano, Carmen +197 morecore +1 more sourceCell surface membrane proteins as personalized biomarkers: where we stand and where we are headed [PDF]
, 2013 Personalized medicine requires the development of a wide array of biomarker diagnostic assays, reflecting individual variations and thus allowing tailored therapeutic interventions.Szabó, Edit, Sarkadi, Balázs, Várady, György, Németh, Adrienn, Cserepes, Judit +4 morecore +1 more sourceCurrent Cancer Biomarkers
, 2023 Current Cancer Biomarkers is a comprehensive review on the status of biological markers for various types of cancer. It aims to update readers on current developments on the subject.-core +1 more sourcePeptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers [PDF]
, 2011 <p><b>Background:</b> Today, dementias are diagnosed late in the course of disease. Future treatments have to start earlier in the disease process to avoid disability requiring new diagnostic tools.Jahn Holger, Thomas J Raedler, William Mullen, Kellmann Markus, Arlt Sönke, Eichenlaub, M., Zürbig Petra, Kellmann, M., Jahn, H., Wittke Stefan, Mischak Harald, Stefan Wittke, Mischak, H., Petra Zürbig, Thomas J. Raedler, Z, P., Mullen, W., Wittke, S., Holger Jahn, Mullen William, Wiedemann Klaus, Harald Mischak, Markus Kellmann, Klaus Wiedemann, Martin Eichenlaub, Raedler Thomas J., Sönke Arlt, Eichenlaub Martin +27 morecore +1 more sourceMulticentric validation of proteomic biomarkers in urine specific for diabetic nephropathy [PDF]
, 2010 Background: Urine proteome analysis is rapidly emerging as a tool for diagnosis and prognosis in disease states. For diagnosis of diabetic nephropathy (DN), urinary proteome analysis was successfully applied in a pilot study.Navis, G.J., Zürbig, P., Fuchs, S., Winklhofer-Roob, B.M., Cerna Marie, Rossing Peter, Federici, M., Bakker Stephan J. L., Fischer Christine, Bakker, Stephan J. L.; id_orcid, Fuchs Sebastian, Zurbig, Petra, Rychlik, Ivan, Rychlík, I., Karel Medek, Navis, Gerjan J., Fischer, Christine, Cerna, Marie, Rossing, K., Gerjan J. Navis, Mischak Harald, Sebastian Fuchs, Stephan J L Bakker, Bilo Henk J. G., Mischak, H., Kasper Rossing, Medek, K., Rossing Kasper, PREDICTIONS Group, Bilo, H.J.G., Medek, Karel, null null, Fischer, C., Johannes M. Roob, Roob Johannes M., Alkhalaf, A., Mischak, Harald, Cerna, M., Janssen, Bart, Fuchs, Sebastian, Bakker, S.J.L., Johannes M Roob, Alaa Alkhalaf, Janssen, B., Bakker, Stephan J. L., Ivan Rychlík, Brigitte M. Winklhofer-Roob, Tiran, Beate, Rychlík Ivan, Roob, Johannes M., Zürbig Petra, Sourij, H., Tiran Beate, Bilo, Henk J. G., Rossing, Peter, Sourij Harald, Winklhofer-Roob, Brigitte M., Navis Gerjan J., Gerjan J Navis, Marie Cerna, Alkhalaf, Alaa, Henk J G Bilo, Christine Fischer, Petra Zürbig, Janssen Bart, Peter Rossing, Bart Janssen, Henk J. G. Bilo, Alkhalaf Alaa, Medek Karel, Harald Mischak, Stephan J. L. Bakker, Tiran, B., Rossing, P., Brigitte M Winklhofer-Roob, Sourij, Harald, Rossing, Kasper, Roob, J.M., Harald Sourij, Beate Tiran, Winklhofer-Roob Brigitte M. +80 morecore +1 more sourceBiomarkers and Lung Cancer Early Detection: State of the Art
, 2021 Lung cancer burden is increasing, with 2 million deaths/year worldwide. Current limitations in early detection impede lung cancer diagnosis when the disease is still localized and thus more curable by surgery or multimodality treatment.Fabrizio Bianchi, Tommaso Colangelo, Marinos Kallikourdis, Elisa Dama, Emanuela Fina, Marco Cremonesi, Giulia Veronesi +6 morecore +1 more sourceEmerging Biomarkers and the Changing Landscape of Small Cell Lung Cancer
, 2022 SIMPLE SUMMARY: Small cell lung cancer (SCLC) is an aggressive cancer representing 15% of all lung cancers. Unlike other types of lung cancer, treatments for SCLC have changed very little in the past 20 years and therefore, the survival rate remains low. Anna Keogh, Stephen Finn, Keogh, Anna, Radonic, Teodora, Finn, Stephen, Teodora Radonic +5 morecore +1 more source