Results 1 to 10 of about 1,344,517 (267)

Determining cut-points for Alzheimer's disease biomarkers: statistical issues, methods and challenges. [PDF]

open access: yes, 2012
New proposed criteria for the clinical diagnosis of Alzheimer's disease increasingly incorporate biomarkers, most of which are normally measured on a continuous scale. Operationalizing such criteria thus requires continuous biomarkers to be dichotomized,
Skillbäck, Tobias,   +10 more
core   +1 more source

Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat [PDF]

open access: yes, 2012
Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were ...
Hanig, J.   +23 more
core   +1 more source

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey [PDF]

open access: yes, 2014
We investigated the use of Alzheimer's disease (AD) biomarkers in European Alzheimer's Disease Consortium centers and assessed their perceived usefulness for the etiologic diagnosis of mild cognitive impairment (MCI).
Erikdotter, M   +197 more
core   +1 more source

Update on Biomarkers Associated with Large-Artery Atherosclerosis Stroke

open access: yes, 2023
Intracranial and extracranial large-artery atherosclerosis (LAA) are a main cause of ischemic stroke. Biomarkers may aid in the diagnosis of LAA and help to stratify patients’ risk of stroke.
Ana Catarina Fonseca, Madalena Rosário
core   +1 more source

Cell surface membrane proteins as personalized biomarkers: where we stand and where we are headed [PDF]

open access: yes, 2013
Personalized medicine requires the development of a wide array of biomarker diagnostic assays, reflecting individual variations and thus allowing tailored therapeutic interventions.
Szabó, Edit   +4 more
core   +1 more source

Current Cancer Biomarkers

open access: yes, 2023
Current Cancer Biomarkers is a comprehensive review on the status of biological markers for various types of cancer. It aims to update readers on current developments on the subject.
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core   +1 more source

Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers [PDF]

open access: yes, 2011
<p><b>Background:</b> Today, dementias are diagnosed late in the course of disease. Future treatments have to start earlier in the disease process to avoid disability requiring new diagnostic tools.
Jahn Holger   +27 more
core   +1 more source

Multicentric validation of proteomic biomarkers in urine specific for diabetic nephropathy [PDF]

open access: yes, 2010
Background: Urine proteome analysis is rapidly emerging as a tool for diagnosis and prognosis in disease states. For diagnosis of diabetic nephropathy (DN), urinary proteome analysis was successfully applied in a pilot study.
Navis, G.J.   +80 more
core   +1 more source

Biomarkers and Lung Cancer Early Detection: State of the Art

open access: yes, 2021
Lung cancer burden is increasing, with 2 million deaths/year worldwide. Current limitations in early detection impede lung cancer diagnosis when the disease is still localized and thus more curable by surgery or multimodality treatment.
Fabrizio Bianchi   +6 more
core   +1 more source

Emerging Biomarkers and the Changing Landscape of Small Cell Lung Cancer

open access: yes, 2022
SIMPLE SUMMARY: Small cell lung cancer (SCLC) is an aggressive cancer representing 15% of all lung cancers. Unlike other types of lung cancer, treatments for SCLC have changed very little in the past 20 years and therefore, the survival rate remains low.
Anna Keogh   +5 more
core   +1 more source

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