Results 31 to 40 of about 1,486,593 (315)

Cell surface membrane proteins as personalized biomarkers: where we stand and where we are headed [PDF]

, 2013
Personalized medicine requires the development of a wide array of biomarker diagnostic assays, reflecting individual variations and thus allowing tailored therapeutic interventions.
Szabó, Edit, Sarkadi, Balázs, Várady, György, Németh, Adrienn, Cserepes, Judit   +4 more
core   +1 more source

Variability of the Genes Involved in the Cellular Redox Status and Their Implication in Drug Hypersensitivity Reactions

Antioxidants, 2021
Adverse drug reactions are a major cause of morbidity and mortality. Of the great diversity of drugs involved in hypersensitivity drug reactions, the most frequent are non-steroidal anti-inflammatory drugs followed by β-lactam antibiotics.
Pedro Ayuso, Elena García-Martín, José A. G. Agúndez   +2 more
doaj   +1 more source

Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers [PDF]

, 2011
<p><b>Background:</b> Today, dementias are diagnosed late in the course of disease. Future treatments have to start earlier in the disease process to avoid disability requiring new diagnostic tools.
Jahn Holger, Thomas J Raedler, William Mullen, Kellmann Markus, Arlt Sönke, Eichenlaub, M., Zürbig Petra, Kellmann, M., Jahn, H., Wittke Stefan, Mischak Harald, Stefan Wittke, Mischak, H., Petra Zürbig, Thomas J. Raedler, Z, P., Mullen, W., Wittke, S., Holger Jahn, Mullen William, Wiedemann Klaus, Harald Mischak, Markus Kellmann, Klaus Wiedemann, Martin Eichenlaub, Raedler Thomas J., Sönke Arlt, Eichenlaub Martin   +27 more
core   +1 more source

GNL3 and PA2G4 as Prognostic Biomarkers in Prostate Cancer [PDF]

, 2023
Prostate cancer is a multifocal and heterogeneous disease common in males and remains the fifth leading cause of cancer-related deaths worldwide. The prognosis of prostate cancer is variable and based on the degree of cancer and its stage at the time of ...
Shashank Kumar, Mohd Shuaib, Abdullah F. AlAsmari, Sanjay Gupta, Faleh Alqahtani   +4 more
core   +1 more source

Biomarkers for Sepsis [PDF]

BioMed Research International, 2014
Bloodstream infections are a major concern because of high levels of antibiotic consumption and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a small percentage of patients with signs and symptoms of sepsis. Biomarkers are widely used in clinical practice and they are useful for monitoring the infectious process.
Henriquez-Camacho, Cesar, Losa, Juan
openaire   +3 more sources

Multicentric validation of proteomic biomarkers in urine specific for diabetic nephropathy [PDF]

, 2010
Background: Urine proteome analysis is rapidly emerging as a tool for diagnosis and prognosis in disease states. For diagnosis of diabetic nephropathy (DN), urinary proteome analysis was successfully applied in a pilot study.
Navis, G.J., Zürbig, P., Fuchs, S., Winklhofer-Roob, B.M., Cerna Marie, Rossing Peter, Federici, M., Bakker Stephan J. L., Fischer Christine, Bakker, Stephan J. L.; id_orcid, Fuchs Sebastian, Zurbig, Petra, Rychlik, Ivan, Rychlík, I., Karel Medek, Navis, Gerjan J., Fischer, Christine, Cerna, Marie, Rossing, K., Gerjan J. Navis, Mischak Harald, Sebastian Fuchs, Stephan J L Bakker, Bilo Henk J. G., Mischak, H., Kasper Rossing, Medek, K., Rossing Kasper, PREDICTIONS Group, Bilo, H.J.G., Medek, Karel, null null, Fischer, C., Johannes M. Roob, Roob Johannes M., Alkhalaf, A., Mischak, Harald, Cerna, M., Janssen, Bart, Fuchs, Sebastian, Bakker, S.J.L., Johannes M Roob, Alaa Alkhalaf, Janssen, B., Bakker, Stephan J. L., Ivan Rychlík, Brigitte M. Winklhofer-Roob, Tiran, Beate, Rychlík Ivan, Roob, Johannes M., Zürbig Petra, Sourij, H., Tiran Beate, Bilo, Henk J. G., Rossing, Peter, Sourij Harald, Winklhofer-Roob, Brigitte M., Navis Gerjan J., Gerjan J Navis, Marie Cerna, Alkhalaf, Alaa, Henk J G Bilo, Christine Fischer, Petra Zürbig, Janssen Bart, Peter Rossing, Bart Janssen, Henk J. G. Bilo, Alkhalaf Alaa, Medek Karel, Harald Mischak, Stephan J. L. Bakker, Tiran, B., Rossing, P., Brigitte M Winklhofer-Roob, Sourij, Harald, Rossing, Kasper, Roob, J.M., Harald Sourij, Beate Tiran, Winklhofer-Roob Brigitte M.   +80 more
core   +1 more source

Emerging Blood-Based Biomarkers for Predicting Immunotherapy Response in NSCLC [PDF]

, 2022
SIMPLE SUMMARY: Treatment with immunotherapy has been established as a standard treatment for lung cancer in recent years. Unfortunately, still, only a small proportion of patients benefit from the treatment, being the first leading cause of cancer death
Fonseca, Pablo, Oitabén, Ana, García-Benito, Carme, Juaneda-Magdalena, Laura, Carme García-Benito, Ana Oitabén, Clara González-Ojea, Martín E. Lázaro, Martínez-Fernández, Mónica, Lázaro, Martín E., Pablo Fonseca, Laura Juaneda-Magdalena, María J. Villanueva, Alberto Garrido-Fernández, López-López, Aida, González-Ojea, Clara, Mónica Martínez-Fernández, Aida López-López, Garrido-Fernández, Alberto, Villanueva, María J.   +19 more
core   +1 more source

Characterization of Antibodies that Detect Human GFAP after Traumatic Brain Injury

Biomarker Insights, 2012
After traumatic brain injury (TBI), glial fibrillary acidic protein (GFAP) and other brain-derived proteins and their breakdown products are released into biofluids such as CSF and blood.
J. Susie Zoltewicz, Dancia Scharf, Boxuan Yang, Aarti Chawla, Kimberly J. Newsom, Lijuan Fang   +5 more
doaj   +1 more source

Profiling plasma peptides for the identification of potential ageing biomarkers in Chinese Han adults [PDF]

, 2012
Advancing age is associated with cardiovascular disease, diabetes mellitus and cancer, and shows significant inter-individual variability. To identify ageing-related biomarkers we performed a proteomic analysis on 1890 Chinese Han individuals, 1136 males
Manshu Song (153063), Xinwei Yu (153054), Feifei Zhao, Li, Y., Manshu Song, Jingjing Wu (153040), Alan H Bittles, Jiapeng Lu (153024), Zhang, Y., Jiapeng Lu, Wei Wang, Wang, Youxin, Yu, Xinwei, Meng, S., Wu, Jingjing, Song, Manshu, Huang, Y., Qingwei Ma (153058), Chang, Naibai, Shijiao Meng, Meng, Shijiao, Shijiao Meng (153050), Wang, Y., Naibai Chang, Xinwei Yu, Zhang, Youjun, Wang, Wei, Huang, Yuqing, Naibai Chang (153067), Yuqing Huang, Qingwei Ma, Yujun Zhang, Youxin Wang (153032), Yuqing Huang (153028), Alan H. Bittles (153071), Li, Yan, Yan Li (23143), Wei Wang (17594), Zhao, Feifei, Chang, N., Bittles, A.H., Yan Li, Song, M., Yujun Zhang (118792), Yu, X., Feifei Zhao (153044), Ma, Qingwei, Wu, J., Zhao, F., Lu, Jiapeng, Bittles, Alan H., Lu, J., Jingjing Wu, Ma, Q., Youxin Wang, Wang, W.   +55 more
core   +2 more sources

Serum-Exosome-Derived miRNAs Serve as Promising Biomarkers for HCC Diagnosis [PDF]

, 2022
Background: Serum exosomes are emerging as key liquid biopsy biomarkers for the early diagnosis of cancer. However, the proportion and distribution of small RNA (sRNA) species from serum exosomes of hepatocellular carcinoma (HCC) patients remain unclear.
Ning Tang, Tao Rui, Jufeng Guo, Zonglei Mao, Xiaobing Zhang, Jian Liu, Aizhai Xiang   +6 more
core   +1 more source