Results 41 to 50 of about 1,640,663 (265)

Phospholipids profiling and outcome of peritoneal dialysis patients

, 2014
Objectives: To investigate phospholipids (PLs) biomarkers in predicting outcome of patients undergoing peritoneal dialysis (PD). Materials and methods: Twenty PD patients were followed using baseline plasma PLs with an improved online two-dimensional ...
Li, Min, Tang, Wen, Lu, Xin-Hong, Wang, Tao, Liu, Hu-Wei   +4 more
core   +1 more source

Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model

Arthritis Research & Therapy, 2019
Background Pain is a debilitating symptom of rheumatoid arthritis (RA), caused by joint inflammation and cartilage and bone destruction. Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat pain and inflammation in RA, but are not disease ...
Anna Katri, Aneta Dąbrowska, Henrik Löfvall, Ming Ding, Morten A. Karsdal, Kim V. Andreassen, Christian S. Thudium, Kim Henriksen   +7 more
doaj   +1 more source

Traditional and Digital Biomarkers: Two Worlds Apart?

, 2019
The identification and application of biomarkers in the clinical and medical fields has an enor - mous impact on society. The increase of digital devices and the rise in popularity of health- related mobile apps has produced a new trove of biomarkers ...
Miho, Enkelejda, Babrak, Lmar
core   +1 more source

The Current Landscape of Glioblastoma Biomarkers in Body Fluids

, 2023
Glioblastoma (GBM) is a highly aggressive and lethal primary brain cancer that necessitates early detection and accurate diagnosis for effective treatment and improved patient outcomes.
Mohammad Doroudian, Fatemeh Farjadian, Soumya Rahima Benhabbour, Nazanin Esmaelizad, Elham Abbasgholinejad, Saba Zanganeh   +5 more
core   +1 more source

Biomarkers of Type IV Collagen Turnover Reflect Disease Activity in Patients with Early-Stage Non-Alcoholic Fatty Liver (NAFL) [PDF]

, 2023
Background: Identification of progressive liver disease necessitates the finding of novel non-invasive methods to identify and monitor patients in need of early intervention.
Ida Lønsmann, Jane I. Grove, Kaye, Philip, Asma Haider, Morten A. Karsdal, Diana J. Leeming, Grove, Jane I., Aithal, Guruprasad P., Philip Kaye, Guruprasad P. Aithal, Haider, Asma, Leeming, Diana J., Lønsmann, Ida, Karsdal, Morten A.   +13 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology

Journal of Experimental & Clinical Cancer Research, 2019
The extracellular matrix (ECM) plays an important role in cancer progression. It can be divided into the basement membrane (BM) that supports epithelial/endothelial cell behavior and the interstitial matrix (IM) that supports the underlying stromal ...
Neel I. Nissen, Morten Karsdal, Nicholas Willumsen   +2 more
doaj   +1 more source

Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway

Journal of Experimental & Clinical Cancer Research, 2022
Background Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in ...
Yujia Li, Hui Chen, Qi Yang, Lixin Wan, Jing Zhao, Yuanyuan Wu, Jiaxin Wang, Yating Yang, Menglan Niu, Hongliang Liu, Junqi Liu, Hushan Yang, Shaogui Wan, Yanming Wang, Dengke Bao   +14 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Functional polymorphisms of caveolin-1 variants as potential biomarkers of esophageal squamous cell carcinoma

, 2014
Objective: To investigate the association of caveolin-1 (CAV1) genetic variants (C239A (rs1997623), G14713A (rs3807987), G21985A (rs12672038), T29107A (rs7804372)) with esophageal squamous cell carcinoma (ESCC) susceptibility.
Chen, Ziping, Liu, Ying, Changqing Xu, Wang, Shanshan, Zhang, Chuanzhen, Ying Liu, Ziping Chen, Xu, Changqing, Shanshan Wang, Chuanzhen Zhang   +9 more
core   +1 more source