Results 11 to 20 of about 2,018,528 (308)

Biomarkers [PDF]

Wiener Medizinische Wochenschrift, 2012
Biomarkers are characteristics objectively measured and evaluated as indicators of: normal biologic processes, pathogenic processes, or pharmacologic response(s) to a therapeutic intervention. In environmental research and risk assessment, biomarkers are frequently referred to as indicators of human or environmental hazards.
Harmony, Larson, Elena, Chan, Sucha, Sudarsanam, Dale E, Johnson   +3 more
  +7 more sources

Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics [PDF]

, 2012
Background: Lipids have critical functions in cellular energy storage, structure and signaling. Many individual lipid molecules have been associated with the evolution of prostate cancer; however, none of them has been approved to be used as a ...
AA Elgamal, B Brügger, BR Pflug, CG Rogers, Charles Pound, Christina Lynn Addison, D Pchejetski, EF Petricoin, F Bravi, F Teichert, FL Crowe, G Balogh, G Draisma, G Liebisch, H He, HK Min, IM Thompson, IM Thompson, J Ding, J Graessler, J Graessler, J Kurhanewicz, Jeffrey Henegar, Jinghe Mao, JR Graff, Junmei Ai, K Athenstaedt, K Ekroos, K Simons, KA Landers, KH Pietiläinen, KR Keshari, L Zhuang, M Kolak, M Lankinen, M Ollero, Mary R. Roth, MG Swanson, ML Ramírez, O Quehenberger, R Bartz, R Etzioni, R Görke, R Welti, RJ Hamilton, RS Kirby, Ruth Welti, S Devaiah, Steven A. Bigler, TC Gibbs, VD de Mello, VL Freeman, X Han, X Han, X Zhou, Xinchun Zhou, Y Xie, Y Zeng, Youping Deng   +58 more
core   +11 more sources

Environmental risk factors and their footprints in vivo – a proposal for the classification of oxidative stress biomarkers [PDF]

, 2020
Environmental agents, including socioeconomic condition, and host factors can act as causal agents and risk factors in disease. We use biomarkers and sociomarkers to study causal factors, such as overproduction of reactive oxygen species (ROS) which ...
Ghezzi, Pietro
core   +1 more source

Imaging Biomarkers or Biomarker Imaging? [PDF]

Pharmaceuticals, 2014
Since biomarker imaging is traditionally understood as imaging of molecular probes, we highly recommend to avoid any confusion with the previously defined term “imaging biomarkers” and, therefore, only use “molecular probe imaging (MPI)” in that context. Molecular probes (MPs) comprise all kinds of molecules administered to an organism which inherently
Markus Mitterhauser, Wolfgang Wadsak
openaire   +3 more sources

Biomarker Jeopardy

Journal of the Advanced Practitioner in Oncology, 2022
In the popular Biomarker Jeopardy session, Sandra E. Kurtin, PhD, ANP-C, AOCN®, Alyssa Henglefelt, PharmD, BCOP, and Haleigh Mistry, MS, PA-C, paired biomarkers with tumor types for which their expression is most commonly used to determine targeted therapy, identified key assays used to measure common biomarkers, and discussed guidelines for biomarker ...
Kurtin, Sandra E., Henglefelt, Alyssa, Mistry, Haleigh   +2 more
openaire   +2 more sources

Epilepsy biomarkers [PDF]

Epilepsia, 2013
SummaryA biomarker is defined as an objectively measured characteristic of a normal or pathologic biologic process. Identification and proper validation of biomarkers of epileptogenesis (the development of epilepsy) and ictogenesis (the propensity to generate spontaneous seizures) might predict the development of an epilepsy condition; identify the ...
Pitkänen, Asla, Loeb, Jeffrey, Dudek, F, Bertram, Edward, Cole, Andrew, Moshé, Solomon, Wiebe, Samuel, Jensen, Frances, Mody, Istvan, Nehlig, Astrid, Vezzani, Annamaria, Engel, Jerome   +11 more
openaire   +5 more sources

The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting [PDF]

, 2019
The 2018 FARA Biomarker Meeting highlighted the current state of development of biomarkers for Friedreich's ataxia. A mass spectroscopy assay to sensitively measure mature frataxin (reduction of which is the root cause of disease) is being developed ...
Blair, Ian A., Farmer, Jennifer, Hersch, Steven, Larkindale, Jane, Lynch, David R., Napierala, Jill, Napierala, Marek, Payne, R. Mark, Subramony, Sub H.   +8 more
core   +1 more source

The dual amylin and calcitonin receptor agonist KBP-089 and the GLP-1 receptor agonist liraglutide act complimentarily on body weight reduction and metabolic profile

BMC Endocrine Disorders, 2021
Background Weight loss therapy is becoming more and more important, and two classes of molecules, namely amylin receptor and GLP-1 receptor agonists, have shown promise in this regard.
Anna Thorsø Larsen, Sofie Gydesen, Nina Sonne, Morten Asser Karsdal, Kim Henriksen   +4 more
doaj   +1 more source

Biomarker Jeopardy

Journal of the Advanced Practitioner in Oncology, 2021
The popular Biomarker Jeopardy session returned this year at JADPRO Live 2020. Sandra E. Kurtin, PhD, ANP-C, AOCN®, led the session, and was joined by Alyssa Henglefelt, PharmD, BCOP, and Allyson Price, PA-C. Using a Jeopardy format, they identified specific biomarkers while discussing targeted therapies and class effects APs should be aware of.
Kurtin, Sandra E., Henglefelt, Alyssa, Price, Allyson   +2 more
openaire   +3 more sources

Co-enrichment of CD8-positive T cells and macrophages is associated with clinical benefit of tislelizumab in solid tumors

Biomarker Research, 2023
Background Activated immune cells (IC) in the tumor microenvironment (TME) are critical for anti-tumor efficacy. Greater understanding of the dynamic diversity and crosstalk between IC is needed to clarify their association with immune checkpoint ...
Dingwei Ye, Jayesh Desai, Jingwen Shi, Si-Yang Maggie Liu, Wei Shen, Tengfei Liu, Yang Shi, Dan Wang, Liang Liang, Silu Yang, Xiaopeng Ma, Wei Jin, Pei Zhang, Ruiqi Huang, Zhirong Shen, Yun Zhang, Yi-Long Wu   +16 more
doaj   +1 more source