Results 11 to 20 of about 90,829,949 (240)
Food and Agricultural Immunology, 2021 Fructooligosaccharides (FOS), a prebiotic supplement, can enhance immunological responses, probably through regulation of gastrointestinal microflora. On the other hand, some environmental pollutants have adjuvanticity against allergic reactions/diseases.
Akiko Yasuda +4 more
doaj +1 more source
Anti–IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels [PDF]
Journal of Allergy and Clinical Immunology, 2008 Anti-IL-5 might be a useful therapeutic agent for eosinophilic disorders, yet its immunologic consequences have not been well characterized.We sought to characterize the hematologic and immunologic effects of anti-IL-5 in human subjects.The effects of 3-month infusions of mepolizumab were assessed in 25 patients with a variety of eosinophilic syndromes.
Miguel L, Stein +6 more
openaire +2 more sources
Food and Agricultural Immunology, 2019 We examined the effects of Bifidobacterium longum IM55, Lactobacillus plantarum IM76, and their (1:1 and 1:9) mixtures (PMs) on house dust mite allergen extract (HDMA)-induced allergic rhinitis (AR) in mice.
Jeon-Kyung Kim +4 more
doaj +1 more source
IL-27 regulates IL-18 binding protein in skin resident cells [PDF]
, 2012 IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M +23 more
core +2 more sources
BALB/c mice deficient in CD4(+) T cell IL-4R alpha expression control Leishmania mexicana load although female but not male mice develop a healer phenotype [PDF]
, 2011 Immunologically intact BALB/c mice infected with Leishmania mexicana develop non-healing progressively growing lesions associated with a biased Th2 response while similarly infected IL-4R alpha-deficient mice fail to develop lesions and develop a robust ...
Owain R Millington +29 more
core +3 more sources
Cells, 2023 Asthma is a chronic complex pulmonary disease characterized by airway inflammation, remodeling, and hyperresponsiveness. Vascular endothelial growth factor (VEGF) and eosinophil-derived neurotoxin (EDN) are two significant mediators involved in the ...
Maciej Tota +4 more
doaj +1 more source
Медицинская иммунология, 2014 . Spearman rank correlation analysis was applied to assess some interrelations between morphological abnormalities of spermatozoids in males with long-term infertility, and cytokine levels in their seminal plasma. Such statistical analysis has revealed a
B. I. Aisikovich +3 more
doaj +1 more source
Anti-il-5 in pediatric allergic diseases [PDF]
Pediatric Allergy and Immunology, 2020 Interleukin (IL)-5 is a potent mediator of the inflammatory cascade in the allergic response.Its predominant role in atopic reactions makes this cytokine an ideal target for blocking the eosinophilic inflammatory hyper-responsiveness to allergens.
Laura Tenero +3 more
openaire +3 more sources
Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]
, 2010 If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow +38 more
core +1 more source
Biomedicines, 2023 Background: it has been suggested that chronic low-grade inflammation plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS).
Elena Vasyukova +8 more
doaj +1 more source