Results 21 to 30 of about 1,825,564 (240)

Study of immunological parameters associated with asthma with and without bacterial infection in Thi-Qar Province [PDF]

open access: yesRomanian Journal of Medical Practice
Background. Asthma is a prevalent and persistent respiratory condition that impacts more than 300 million individuals globally, leading to substantial illness and death. Objective.
Huda Kareem ABBAS, Huda Kareem ABBAS
doaj   +1 more source

Dietary supplementation with fructooligosaccharides ameliorates allergy development following DEHP exposure in mice

open access: yesFood and Agricultural Immunology, 2021
Fructooligosaccharides (FOS), a prebiotic supplement, can enhance immunological responses, probably through regulation of gastrointestinal microflora. On the other hand, some environmental pollutants have adjuvanticity against allergic reactions/diseases.
Akiko Yasuda   +4 more
doaj   +1 more source

Anti–IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2008
Anti-IL-5 might be a useful therapeutic agent for eosinophilic disorders, yet its immunologic consequences have not been well characterized.We sought to characterize the hematologic and immunologic effects of anti-IL-5 in human subjects.The effects of 3-month infusions of mepolizumab were assessed in 25 patients with a variety of eosinophilic syndromes.
Miguel L, Stein   +6 more
openaire   +2 more sources

Anti-il-5 in pediatric allergic diseases [PDF]

open access: yesPediatric Allergy and Immunology, 2020
Interleukin (IL)-5 is a potent mediator of the inflammatory cascade in the allergic response.Its predominant role in atopic reactions makes this cytokine an ideal target for blocking the eosinophilic inflammatory hyper-responsiveness to allergens.
Laura Tenero   +3 more
openaire   +3 more sources

Bifidobacterium longum and Lactobacillus plantarum alleviate house dust mite allergen-induced allergic rhinitis by regulating IL-4, IL-5, and IL-10 expression

open access: yesFood and Agricultural Immunology, 2019
We examined the effects of Bifidobacterium longum IM55, Lactobacillus plantarum IM76, and their (1:1 and 1:9) mixtures (PMs) on house dust mite allergen extract (HDMA)-induced allergic rhinitis (AR) in mice.
Jeon-Kyung Kim   +4 more
doaj   +1 more source

The Role of Eosinophil-Derived Neurotoxin and Vascular Endothelial Growth Factor in the Pathogenesis of Eosinophilic Asthma

open access: yesCells, 2023
Asthma is a chronic complex pulmonary disease characterized by airway inflammation, remodeling, and hyperresponsiveness. Vascular endothelial growth factor (VEGF) and eosinophil-derived neurotoxin (EDN) are two significant mediators involved in the ...
Maciej Tota   +4 more
doaj   +1 more source

MODES OF INTERACTION BETWEEN SPERMATOZOID ABNORMALITIES AND CYTOKINES IN SEMINAL PLASMA FROM INFERTILE MALES

open access: yesМедицинская иммунология, 2014
. Spearman rank correlation analysis was applied to assess some interrelations between morphological abnormalities of spermatozoids in males with long-term infertility, and cytokine levels in their seminal plasma. Such statistical analysis has revealed a
B. I. Aisikovich   +3 more
doaj   +1 more source

Targeting IL-5 in COPD.

open access: yesInternational journal of chronic obstructive pulmonary disease, 2019
Many patients with chronic obstructive pulmonary disease (COPD) continue to experience exacerbations despite receiving standard-of-care treatments. Novel approaches to COPD treatment focus on understanding and targeting molecular mechanisms of airway inflammation, airway obstruction, remodeling and lung destruction.
Narendra,Dharani K., Hanania,Nicola A.
openaire   +5 more sources

Inflammatory and Anti-Inflammatory Parameters in PCOS Patients Depending on Body Mass Index: A Case-Control Study

open access: yesBiomedicines, 2023
Background: it has been suggested that chronic low-grade inflammation plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS).
Elena Vasyukova   +8 more
doaj   +1 more source

Serum IL-5, POSTN and IL-33 levels in chronic rhinosinusitis with nasal polyposis correlate with clinical severity

open access: yesBMC Immunology, 2022
Background Chronic rhinosinusitis (CRS) is a group of heterogeneous diseases characterized by epithelial inflammation and tissue eosinophilic infiltration.
Hanna Zielińska-Bliźniewska   +5 more
doaj   +1 more source

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