Results 21 to 30 of about 17,201,482 (284)

Targeting IL-5 in COPD.

International journal of chronic obstructive pulmonary disease, 2019
Many patients with chronic obstructive pulmonary disease (COPD) continue to experience exacerbations despite receiving standard-of-care treatments. Novel approaches to COPD treatment focus on understanding and targeting molecular mechanisms of airway inflammation, airway obstruction, remodeling and lung destruction.
Narendra,Dharani K., Hanania,Nicola A.
openaire   +5 more sources

Inflammatory and Anti-Inflammatory Parameters in PCOS Patients Depending on Body Mass Index: A Case-Control Study

Biomedicines, 2023
Background: it has been suggested that chronic low-grade inflammation plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS).
Elena Vasyukova, Ekaterina Zaikova, Olga Kalinina, Inga Gorelova, Irina Pyanova, Elena Bogatyreva, Elena Vasilieva, Elena Grineva, Polina Popova   +8 more
doaj   +1 more source

Serum IL-5, POSTN and IL-33 levels in chronic rhinosinusitis with nasal polyposis correlate with clinical severity

BMC Immunology, 2022
Background Chronic rhinosinusitis (CRS) is a group of heterogeneous diseases characterized by epithelial inflammation and tissue eosinophilic infiltration.
Hanna Zielińska-Bliźniewska, Milena Paprocka-Zjawiona, Anna Merecz-Sadowska, Radosław Zajdel, Katarzyna Bliźniewska-Kowalska, Katarzyna Malinowska   +5 more
doaj   +1 more source

In vitro Culture with Cytokines Provides a Tool to Assess the Effector Functions of ILC2s in Peripheral Blood in Asthma

Journal of Asthma and Allergy, 2021
Li Y Drake,1,2 Kathleen R Bartemes,1,3 Kay A Bachman,1 John B Hagan,1 Hirohito Kita1,4 1Division of Allergic Diseases and Department of Medicine, Mayo Clinic, Rochester, MN, USA; 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic ...
Drake LY, Bartemes KR, Bachman KA, Hagan JB, Kita H   +4 more
doaj  

Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction

, 2009
IL (interleukin)-4 and IL-13 are key cytokines in the pathogenesis of allergic inflammatory disease. IL-4 and IL-13 share many functional properties as a result of their utilization of a common receptor complex comprising IL-13Ralpha1 (IL-13 receptor ...
Donna E. Davies, Holgate, Stephen T, Isabelle Kirby, Ida Karin Nordgren, Tavassoli, Ali, Davies, Donna E, Holloway, John W, Andrews, Allison-Lynn, Stephen T. Holgate, Nordgren, Ida Karin, John W. Holloway, Kirby, Isabelle, Allison-Lynn Andrews, Ali Tavassoli   +13 more
core   +1 more source

IL-27 regulates IL-18 binding protein in skin resident cells [PDF]

, 2012
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M, Miriam Wittmann, Werfel, Thomas, Bachmann, M, Doble, Rosella, Muehl, H, Thomas Werfel, Doble Rosella, Pfeilschifter, Josef (Prof. Dr.), Doble, R, Heiko Mühl, Mühl Heiko, Malte Bachmann, Wittmann Miriam, Pfeilschifter, J, Wittmann, Miriam, Bachmann Malte, Werfel, T, Josef Pfeilschifter, Werfel Thomas, Bachmann, Malte, Mühl, Heiko, Rosella Doble, Pfeilschifter Josef   +23 more
core   +2 more sources

Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]

, 2013
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Heiko Mühl, Heiko eMühl, Mühl, Heiko
core   +1 more source

Immunological Study for Interleukin-5 and GM-CSF for Complications Post-Wisdom Teeth Extraction

Medical Journal of Babylon
Background:Wisdom teeth extraction is one of the most common operations conducted in dental clinics and the most common duty performed in oral and maxillofacial surgery clinics.
Susan Hameed Uraibi, Baha Hamdi Al-Amiedi, Mahdi Y. Kezar   +2 more
doaj   +1 more source

SERUM LEVELS OF HEMOPOIETIC AND ANGIOGENESIS GROWTH FACTORS (IL-5, IL-7, IL-9, FGF-β, G-CSF, VEGF AND PDGF) IN WOMEN WITH UTERINE MYOMA

Медицинская иммунология, 2018
Uterine leiomyomas are common benign tumors developing from smooth muscle tissues, often leading to infertility and recurrent abortions. Pregnancy and development of uterine fibroids are characterized by an unusual rate of myometrium growth ...
V. I. Konenkov, E. G. Koroleva, N. B. Orlov, V. F. Prokofiev, A. V. Shevchenko, A. M. Novikov   +5 more
doaj   +1 more source

IL-5 in asthma [PDF]

Thorax, 2002
We have recently published two manuscripts on the effects of interleukin (IL)-5 administration to patients with mild asthma in the American Journal of Respiratory & Critical Care Medicine 1 and in Thorax .2 We are addressing this letter to the Editors of both journals.
openaire   +1 more source