Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. [PDF]
Specific differences in signaling and antiviral properties between the different Lambda-interferons, a novel group of interferons composed of IL-28A, IL-28B and IL-29, are currently unknown.
Ralf Bartenschlager +28 more
core +1 more source
Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction
IL (interleukin)-4 and IL-13 are key cytokines in the pathogenesis of allergic inflammatory disease. IL-4 and IL-13 share many functional properties as a result of their utilization of a common receptor complex comprising IL-13Ralpha1 (IL-13 receptor ...
Donna E. Davies +13 more
core +1 more source
In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines [PDF]
We show that a combination of the immunosuppressive drugs, vitamin D3 and Dexamethasone, induced human and mouse naive CD4(+) T cells to differentiate in vitro into regulatory T cells.
Hawrylowicz, C.M. +38 more
core +1 more source
Background Chronic rhinosinusitis (CRS) is a group of heterogeneous diseases characterized by epithelial inflammation and tissue eosinophilic infiltration.
Hanna Zielińska-Bliźniewska +5 more
doaj +1 more source
Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Heiko Mühl, Heiko eMühl, Mühl, Heiko
core +1 more source
Li Y Drake,1,2 Kathleen R Bartemes,1,3 Kay A Bachman,1 John B Hagan,1 Hirohito Kita1,4 1Division of Allergic Diseases and Department of Medicine, Mayo Clinic, Rochester, MN, USA; 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic ...
Drake LY +4 more
doaj
IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo [PDF]
IL-6 plays a pivotal role in favoring T-cell commitment toward a Th17 cell rather than Treg-cell phenotype, as established through in vitro model systems.
Maizels, Rick M. +5 more
core +1 more source
IL-17 does not directly activate neutrophils at 5 hours.
Equine neutrophils (n = 3) were isolated from blood and cultured (5 hours) in presence or absence of IL-17 at different concentrations (ng.ml-1). (A). IL-1β, (B). IL-6 and (C) IL-8 mRNA expression were evaluated by qPCR. Upregulation of all cytokines was
Ruby Yoana Murcia (2637337) +2 more
core +1 more source
Mediators and Cytokines in Persistent Allergic Rhinitis and Nonallergic Rhinitis with Eosinophilia Syndrome [PDF]
Background: Patients with nonallergic rhinitis with eosinophilia syndrome (NARES) show typical symptoms of persistent allergic rhinitis (PAR). The aim of the present study was to compare nasal cytokine patterns between NARES and PAR.
Canis, Martin +9 more
core +1 more source
Immunological Study for Interleukin-5 and GM-CSF for Complications Post-Wisdom Teeth Extraction
Background:Wisdom teeth extraction is one of the most common operations conducted in dental clinics and the most common duty performed in oral and maxillofacial surgery clinics.
Susan Hameed Uraibi +2 more
doaj +1 more source

