Results 51 to 60 of about 1,581,460 (288)

Obesity and Asthma: Adiponectin Receptor 1 (Adipo R1) and Adiponectin Receptor 2 (Adipo R2) are expressed by normal human bronchial epithelial (NHBE) cells at air-liquid interface (ALI) and expression changes with IL-13 stimulation [PDF]

open access: yes, 2016
Obesity is recognized as an important risk factor for the development of many chronic diseases such as hypertension, Type 2 diabetes mellitus (T2DM) cardiovascular disease, cancer, renal disease, neurologic dysfunction, metabolic syndrome and asthma (3 ...
Bradley, Jennifer L
core   +1 more source

Effects of IL-13 on murine listeriosis [PDF]

open access: yesInternational Immunology, 1997
Acquired resistance against Listeria monocytogenes is a typical T helper (Th) 1 dominated immune response, whereas Th2 cytokines are thought to worsen listeriosis. We investigated effects of recombinant IL-13 (rIL-13) on the host response to L. monocytogenes in mice.
Flesch, I., Wandersee, A., Kaufmann, S.
openaire   +3 more sources

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie   +4 more
wiley   +1 more source

Immune mechanisms of atopic dermatitis and new approaches to targeted biological therapy

open access: yesМедицинский совет, 2022
This review presents current data on immunopathogenesis, the role of cytokines in inflammation in atopic dermatitis (AD). The pathogenetic phenotypes of the disease associated with various abnormalities of immune mechanisms and dysfunction of the ...
N. N. Potekaev   +3 more
doaj   +1 more source

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi   +20 more
wiley   +1 more source

Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]

open access: yes, 2013
Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A   +2 more
core   +2 more sources

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges   +12 more
wiley   +1 more source

The Sera levels of Interleukin-13 in Patients with Atopic Dermatitis in Thi-Qar province

open access: yesمجلة علوم ذي قار, 2022
The Interleukin-13 (IL-13) is a component of the innate immune system that is primarily produced by Th2 cells and is found in high concentrations in skin lesions of atopic dermatitis.
Amel A. Naji, Hind M Mousa
doaj   +1 more source

IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension

open access: yesAmerican Journal of Physiology-Lung Cellular and Molecular Physiology, 2013
Although previous literature suggests that interleukin (IL)-13, a T-helper type 2 cell effector cytokine, might be involved in the pathogenesis of pulmonary hypertension (PH), direct proof is lacking. Furthermore, a potential mechanism underlying IL-13-induced PH has never been explored. This study's goal was to investigate the role and mechanism of IL-
Won-Kyung, Cho   +10 more
openaire   +3 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

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