Results 51 to 60 of about 9,970,140 (285)

Pro-inflammatory and counter-regulatory modulators of interleukin-5–driven eosinophil programs: a framework for precision medicine in eosinophilic diseases

Frontiers in Immunology
Interleukin-5 (IL-5) is central to eosinophil differentiation, survival, and activation. Subsequent studies confirmed IL-5 receptor expression and mapped downstream signaling, showing that IL-5 promotes not only survival but also trafficking and effector
Hisashi Sasaki, Jun Miyata, Jun Miyata, Koichi Fukunaga, Koichi Fukunaga   +4 more
doaj   +1 more source

Polyphenol containing Sargassum horneri attenuated Th2 differentiation in splenocytes of ovalbumin-sensitised mice: involvement of the transcription factors GATA3/STAT5/NLRP3 in Th2 polarization

Pharmaceutical Biology, 2021
Context Sargassum horneri (Turner) C. Agardh (Sargassaceae) is a brown marine alga used in oriental medicine to treat allergic conditions. Objective This study clarifies the effect of polyphenol-containing S.
Kalahe Hewage Iresha Nadeeka Madushani Herath, Jinhee Cho, Hyo Jin Kim, Duong Thi Thuy Dinh, Hyun-Soo Kim, Ginnae Ahn, You-Jin Jeon, Youngheun Jee   +7 more
doaj   +1 more source

IL-4 and IL-13-polarized M2 macrophages are deficient in IL-10 and CCL17 secretion.

, 2018
(A) Differential cytokine secretion profiles of M1 macrophages and M2 macrophages exposed to IL-4 and IL-13. (B) Differential cell surface marker expression. MFI indicates mean fluorescence intensity. (C) Differential gene expression. For panels A and C,
Elizabeth M. Jaffee (183374), Elias R. Gerrick (6061385), Kimberline Y. Gerrick (6061382), Anuj Gupta (4328764), Sarah J. Wheelan (200002), Srinivasan Yegnasubramanian (27577)   +5 more
core   +1 more source

IL-27 regulates IL-18 binding protein in skin resident cells [PDF]

, 2012
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M, Miriam Wittmann, Werfel, Thomas, Bachmann, M, Doble, Rosella, Muehl, H, Thomas Werfel, Doble Rosella, Pfeilschifter, Josef (Prof. Dr.), Doble, R, Heiko Mühl, Mühl Heiko, Malte Bachmann, Wittmann Miriam, Pfeilschifter, J, Wittmann, Miriam, Bachmann Malte, Werfel, T, Josef Pfeilschifter, Werfel Thomas, Bachmann, Malte, Mühl, Heiko, Rosella Doble, Pfeilschifter Josef   +23 more
core   +2 more sources

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Evaluation of The Correlation and Reproducibility between Histamine, IL-4, and IL-13 Release from Human Basophils

Iranian Journal of Allergy, Asthma and Immunology, 2014
Human  basophils play a key role in allergic diseases such as asthma and in a variety of  immunological disorders.  The  generation  of  IL-4  and  IL-13  can  be  induced  from basophil  by  IgE-mediated   and   non-IgE-mediated   mechanisms.
Nahid Eskandari, Reza Bastan, Maryam Ahmadi, Peter T Peachell   +3 more
doaj  

Therapeutic Effect of Curcumin on Dermatitis Induced by Acetone in Female Rats

Kufa Journal for Veterinary Medical Sciences, 2023
The aim of this study was to evaluate different concertation of curcumin on induced atopic dermatitis in female Albino rats, particularly, immunomodulatory effect of curcumin in induced dermatitis by pure acetone 99.9% in female rats.
Ameer Al Fatlawy, Shatha Mousa Mlaghee
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

The level of IL-12, IL-10, IL-4, and MMP-13 in cutaneous leishmaniasis patients

Medical Journal of Babylon
Background: Cutaneous leishmaniasis (CL) is a dermatological condition that arises due to the presence of protozoan parasites. The disease disproportionately impacts those residing in economically disadvantaged regions and is closely linked to factors ...
Abrar Kareem Dhari, Ali Mohammed Abed, Suha Maher Abed   +2 more
doaj   +1 more source

The expression levels of IL-4 and IL-13 in the serum and blister fluid of patients with bullous pemphigoid

Pifu-xingbing zhenliaoxue zazhi
Objective To investigate the expression levels of type 2 inflammatory cytokines, IL-4 and IL-13, in the serum and blister fluid of patients with bullous pemphigoid (BP).
Yao ZHOU, Lijun TENG, Guomin LI, Jie XU, Jinjin ZHENG, Hao FANG, Ruzeng XUE   +6 more
doaj   +1 more source