Results 71 to 80 of about 7,622,838 (295)

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Conformational flexibility of an anti-IL-13 DARPin† [PDF]

Protein Engineering, Design and Selection, 2016
Abstract Designed ankyrin repeat proteins (DARPin®) are artificial non-immunoglobulin binding proteins with potential applications as therapeutic molecules. DARPin 6G9 binds interleukin-13 with high affinity and blocks the signaling pathway and as such is promising for the treatment of asthma and other atopic diseases.
Alexey, Teplyakov, Thomas J, Malia, Galina, Obmolova, Steven A, Jacobs, Karyn T, O'Neil, Gary L, Gilliland   +5 more
openaire   +2 more sources

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Inhibitory effects on IL-13-induced TARC production. [PDF]

, 2018
Human PCLS were co-stimulated with 10 nM IL-13 and increasing concentrations of the antagonists a) anti-IL-13 Ab (n = 6), b) anti-IL-4Rα #1 (n = 5), c) anti-IL-4Rα #2 (n = 5), and d) anti-IL-4Rα #3 (n = 4).
Katherina Sewald (303742), Sharon Melissa Jiménez Delgado (6033863), Hans-Gerd Fieguth (309921), Gregor Warnecke (445368), Armin Braun (35630), Mary Fitzgerald (6033872), Danny Jonigk (335316), Olaf Pfennig (309923), Susann Dehmel (4019924), Judy Wichmann (6033875), Sascha Knauf (111363), Olga Danov (3852835), Helena Obernolte (6033866), Peter Braubach (412009), Sophie Seehase (303735), Gabriele Matschiner (6033869)   +15 more
core   +1 more source

Evaluation of The Correlation and Reproducibility between Histamine, IL-4, and IL-13 Release from Human Basophils

Iranian Journal of Allergy, Asthma and Immunology, 2014
Human  basophils play a key role in allergic diseases such as asthma and in a variety of  immunological disorders.  The  generation  of  IL-4  and  IL-13  can  be  induced  from basophil  by  IgE-mediated   and   non-IgE-mediated   mechanisms.
Nahid Eskandari, Reza Bastan, Maryam Ahmadi, Peter T Peachell   +3 more
doaj  

Persistent Effects Induced by IL-13 in the Lung [PDF]

American Journal of Respiratory Cell and Molecular Biology, 2006
Abstract IL-13 overexpression in the lung induces inflammatory and remodeling responses that are prominent features of asthma. Whereas most studies have concentrated on the development of IL-13–induced disease, far fewer studies have focused on the reversibility of IL-13–induced pathologies.
Patricia C, Fulkerson, Christine A, Fischetti, Lynn M, Hassman, Nikolaos M, Nikolaidis, Marc E, Rothenberg   +4 more
openaire   +2 more sources

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections-1 [PDF]

, 2011
Of colon sections are shown from both naïve (i) and pinworm infected mice at 7 (ii) and 14 days PI (iii). Sections were stained with PAS to identify goblet cells. 100× magnification.
Lizette CE Fick (58853), Frank Brombacher (52142), Reece G Marillier (58850), William GC Horsnell (58855), Mosiuoa Leeto (58854), Elizabeth M Smith (58852), Chesney Michels (58851), Benjamin Dewals (40167)   +7 more
core   +1 more source

The level of IL-12, IL-10, IL-4, and MMP-13 in cutaneous leishmaniasis patients

Medical Journal of Babylon
Background: Cutaneous leishmaniasis (CL) is a dermatological condition that arises due to the presence of protozoan parasites. The disease disproportionately impacts those residing in economically disadvantaged regions and is closely linked to factors ...
Abrar Kareem Dhari, Ali Mohammed Abed, Suha Maher Abed   +2 more
doaj   +1 more source

The expression levels of IL-4 and IL-13 in the serum and blister fluid of patients with bullous pemphigoid

Pifu-xingbing zhenliaoxue zazhi
Objective To investigate the expression levels of type 2 inflammatory cytokines, IL-4 and IL-13, in the serum and blister fluid of patients with bullous pemphigoid (BP).
Yao ZHOU, Lijun TENG, Guomin LI, Jie XU, Jinjin ZHENG, Hao FANG, Ruzeng XUE   +6 more
doaj   +1 more source