Results 81 to 90 of about 9,970,140 (285)

The viability and morphology of IL-13- or IL-13+ cell cultures.

open access: yes, 2019
(A) Percentages of cell viability at the end of cultivation of P0, P1, and P2 cultures and percentages of cell viability of the unattached GC-enriched subpopulation harvested on P1d1.
Pavlina Skalicka (3929549)   +4 more
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]

open access: yes, 2011
Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core   +1 more source

NF-κB signaling and crosstalk during carcinogenesis

open access: yes4 open, 2019
Transcription factors (TFs) are proteins that control the transcription of genetic information from DNA to mRNA by binding to specific DNA sequences either on their own or with other proteins as a complex.
Brücher Björn L.D.M.   +2 more
doaj   +1 more source

IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections-3

open access: yes, 2011
Bar) and IL-4/IL-13(gray bar) mice at 8 weeks PI. Data are pooled from 2 to 4 individual experiments. Data are means of these experiments ± SEM. (B) Quantification of goblet cell number per villus in colon of naïve mice and 8 weeks PI from BALB/c (solid ...
Lizette CE Fick (58853)   +7 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

IL-13-induced eotaxin-3 and TARC secretion in human PCLS.

open access: yes, 2018
Lung tissue was stimulated with human IL-13 for 24 h. a) Eotaxin-3 and b) TARC were measured in supernatant and tissue lysate and normalized (as a percentage) to the untreated tissue control. Data are presented as mean ± SEM; group sizes: a) n = 7 and b)
Katherina Sewald (303742)   +15 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Improvement of Oxazolone-Induced Ulcerative Colitis in Rats Using Andrographolide

open access: yesMolecules, 2019
Ulcerative colitis (UC) is usually accompanied with symptoms of abdominal pain, diarrhea, and bloody stool, which impair the quality of life of patients.
Liuhong Zhang   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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