Results 101 to 110 of about 72,327,479 (284)

IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13 [PDF]

, 2008
Background IL-13 is a critical mediator of allergic asthma and associated airway hyperresponsiveness. IL-13 acts through a receptor complex comprised of IL-13Rα1 and IL-4Rα subunits with subsequent activation of signal transducer and activator of ...
Moynihan Barry J, Tolloczko, B, Martin James G, Martin, JG, Laberge, S, Barbara Tolloczko, Pascale Ferraro, Marie-Claire Michoud, Ferraro Pascale, Barry J Moynihan, Tolloczko Barbara, James G Martin, Souad El Bassam, Bassam Souad, Michoud, MC, El Bassam, S, Sophie Laberge, Michoud Marie-Claire, Moynihan, BJ, Ferraro, P, Laberge Sophie   +20 more
core   +1 more source

The expression levels of IL-4 and IL-13 in the serum and blister fluid of patients with bullous pemphigoid

Pifu-xingbing zhenliaoxue zazhi
Objective To investigate the expression levels of type 2 inflammatory cytokines, IL-4 and IL-13, in the serum and blister fluid of patients with bullous pemphigoid (BP).
Yao ZHOU, Lijun TENG, Guomin LI, Jie XU, Jinjin ZHENG, Hao FANG, Ruzeng XUE   +6 more
doaj   +1 more source

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres, Cristina Tarango, Ashley Childress, Chunyan Liu, Evan Thomas, Jennifer Pomales, Eric S. Mullins   +6 more
wiley   +1 more source

IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections-1

, 2011
Of colon sections are shown from both naïve (i) and pinworm infected mice at 7 (ii) and 14 days PI (iii). Sections were stained with PAS to identify goblet cells. 100× magnification.
Lizette CE Fick (58853), Frank Brombacher (52142), Reece G Marillier (58850), William GC Horsnell (58855), Mosiuoa Leeto (58854), Elizabeth M Smith (58852), Chesney Michels (58851), Benjamin Dewals (40167)   +7 more
core   +1 more source

Association of IL‐33 in modeling type‐2 airway inflammation and pulmonary emphysema in mice

Immunity, Inflammation and Disease
We developed pulmonary emphysema and a type 2 airway inflammation overlap mouse model. The bronchoalveolar lavage (BAL) interleukin 13 (IL‐13), IL‐4, and IL‐5 levels in the overlap model were higher than in the pulmonary emphysema model and lower than in
Chika Miyaoka, Masato Watanabe, Keitaro Nakamoto, Yuki Yoshida, Aya Hirata, Jumpei Aso, Hiroki Nunokawa, Manabu Ishida, Koujiro Honda, Saori Takata, Takeshi Saraya, Haruyuki Ishii   +11 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

IL-13 Antibodies Influence IL-13 Clearance in Humans by Modulating Scavenger Activity of IL-13Rα2

, 2011
Human studies using Abs to two different, nonoverlapping epitopes of IL-13 suggested that epitope specificity can have a clinically significant impact on clearance of IL-13.
Donald Raible, Kimberly Marquette, Marion T. Kasaian, Simon Zhou, Timothy A. Cook, Lioudmila Tchistiakova, Xiang-Yang Tan   +6 more
core   +1 more source

Immune and allergic responses to Anisakis pegreffii, with focus on the roles of IL-4, IL-13 and the IL-4 receptor alpha [PDF]

, 2007
Includes bibliographical references (p. 117-127).The fish-parasitizing nematode Anisakis pegreffii induces gastrointestinal disease and allergy when ingested by humans, and can cause occupational allergy in seafood processing workers.
Nieuwenhuizen, Natalie
core   +1 more source

Anticancer and bioactivity effect of the AraA-IL13 fusion protein on the glioblastoma cell line

Research in Pharmaceutical Sciences
Background and purpose: Glioblastoma (GBM) is an aggressive and malignant brain cancer with the highest mortality and low survival rates. To discover a more specific and efficient treatment for GBM, we synthesized and examined the cytotoxic effect of ...
Rezvan Mehrab, Hamid Sedighian, Fattah Sotoodehnejadnematalahi, Raheleh Halabian, Abbas Ali Imanifooladi   +4 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source