Results 21 to 30 of about 2,038,009 (287)

B-cell gene therapy for tolerance induction: host but not donor B cell derived IL-10 is necessary for tolerance

open access: yesFrontiers in Microbiology, 2011
Genetically modified B cells are excellent tolerogenic APCs in multiple models of autoimmunity. However, the mechanisms of action are still not completely understood.
Yan eSu   +6 more
doaj   +1 more source

Differential regulation of anti-inflammatory genes by p38 MAP kinase and MAP kinase kinase 6. [PDF]

open access: yes, 2014
BackgroundConventional p38α inhibitors have limited efficacy in rheumatoid arthritis, possibly because p38 blockade suppresses the counter-regulatory mechanisms that limit inflammation.
Boyle, David L   +3 more
core   +3 more sources

Impact of Anti-Diabetic Treatments on Circulating Anti-Inflammatory Mediators (IL-10 and IL-13) in Type 2 Diabetes Patients [PDF]

open access: yesJournal of Bioscience and Applied Research
Background and Objectives: Type 2 diabetes mellitus (T2DM) is a chronic condition marked by persistent hyperglycemia and low-grade inflammation, involving cytokines like IL-10 and IL-13.
Muhannad Shweash   +4 more
doaj   +1 more source

Changes in novel anti-infalmmatory cytokine concetration in the bood of endurance and race horses at different levels of training

open access: yesComputational and Structural Biotechnology Journal, 2023
Several anti-inflammatory cytokines have been proposed as markers for exercise monitoring in humans such as the interleukin 1 receptor agonist (IL-ra), or interleukin 13 (IL-13).
Urszula Plisak   +4 more
doaj   +1 more source

Relationship between levels of inflammatory cytokines in the genital tract and CD4+ cell counts in women with acute HIV-1 infection. [PDF]

open access: yes, 2008
Inflammatory responses at mucosal surfaces after human immunodeficiency virus type 1 (HIV-1) transmission may influence disease outcome. We evaluated levels of interleukin (IL)-1beta, IL-6, tumor necrosis factor-alpha, IL-8, IL-10, and IL-12 in genital ...
Bebell, Lisa M   +7 more
core   +1 more source

Serum Levels of IL-10 and IL-22 Cytokines in Patients with Psoriasis [PDF]

open access: yesIranian Journal of Immunology, 2016
Background: As a chronic inflammatory condition, psoriasis results from an interaction between genetic and immunologic factors in a predisposing environment. In spite of compelling evidence for the role of T cells and cytokines in psoriasis, interleukin (
Mohammad Reza Sobhan   +4 more
doaj  

Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures

open access: yesJournal of Neuroinflammation, 2019
Background Microglia are important for secreting chemical mediators of inflammatory responses in the central nervous system. Interleukin (IL)-10 and IL-1β secreted by glial cells support neuronal functions, but the related mechanisms remain vague.
Yi Sun   +9 more
doaj   +1 more source

Association of IL-9, IL-10, and IL-17 Cytokines With Hepatic Fibrosis in Human Schistosoma mansoni Infection

open access: yesFrontiers in Immunology, 2021
This is a case series study to evaluate immunological markers associated with schistosomiasis advanced fibrosis, including 69 patients from an endemic area from the State of Sergipe and from the Hepatology Service of the University Hospital in Sergipe ...
Karine Garcez Schuster Franco   +36 more
doaj   +1 more source

Consequences of the Lack of IL-10 in Different Endotoxin Effects and its Relationship With Glucocorticoids [PDF]

open access: yes, 2019
Sepsis constitutes one of the major causes of death in ICUs. In sepsis induced by gram-negative, although lipopolysaccharide (LPS) initially induces an exacerbated secretion of proinflammatory cytokines leading to endotoxic shock and death resembling a ...
Barrientos, Gabriela Laura   +10 more
core   +1 more source

IL-10 -1082 SNP and IL-10 in primary CNS and vitreoretinal lymphomas [PDF]

open access: yesGraefe's Archive for Clinical and Experimental Ophthalmology, 2012
Most primary central nervous system lymphomas (PCNSLs) and primary vitreoretinal lymphomas (PVRLs) are B-cell lymphomas that produce high levels of interleukin (IL)-10, which is linked to rapid disease progression. The IL-10 (-1082) G → A polymorphism (IL-10 SNP) is associated with improved survival in certain non-CNS lymphoma ...
Hema L, Ramkumar   +6 more
openaire   +2 more sources

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