Results 51 to 60 of about 11,738,321 (294)

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

ICOS controls Foxp3+ regulatory T-cell expansion, maintenance, and IL-10 production during helminth infection [PDF]

, 2012
Foxp3+ regulatory T (Treg) cells are key immune regulators during helminth infections, and identifying the mechanisms governing their induction is of principal importance for the design of treatments for helminth infections, allergies and autoimmunity ...
van der Werf, Nienke, MacDonald, Andrew, Redpath, Stephen A, Taylor, Matthew, Cervera, Ana M, Macdonald, Andrew S; id_orcid, Cervera, Ana, Taylor, Matthew D., Maizels, Rick M, Andrew S. MacDonald, Cervera, Ana M., Gray, David, Maizels, Rick, Stephen A. Redpath, Maizels, Rick M., Taylor, Matthew D, Macdonald, Andrew S.; id_orcid, Redpath, Stephen A., Matthew D. Taylor, Rick M. Maizels, David Gray, Nienke van der Werf, Ana M. Cervera   +22 more
core   +1 more source

The Correlation between Interleukin-10 Serum with Bacterial Index in Multidrug Therapy-treated Leprosy Patients

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016
Background: Immune respons disturbance oftenly found in leprosy patient, mainly in various T cell subset and cytokine immune system arranger. Interleukin-10 produced by Th 2 cell, Th3 cell, monocyte, dendritic cell, eosinophil, mast cell, and ...
Eva Krishna Sutedja, Jono Hadi Agusni, Hartati Purbo Dharmadji   +2 more
doaj   +1 more source

IL-10/IL-10 Receptor Signaling Regulates TIMP-1 Expression [PDF]

Cancer Biology & Therapy, 2002
An IL-10 responsive signal protein, termed IL-10E1, was cloned from human prostate cancer PC-3 ML cells based on its binding affinity for a novel enhancer element (i.e., HTE-1: 5’-CACGATGACTCATCACTGTTGAAAGACA-3’) of the Tissue Inhibitor of metalloproteinase-1 (TIMP-1) gene. Electrophoretic mobility shift assays (EMSAs) and enzyme linked immuno-sandwich
Min Wang, Youji Hu, Ischiro Shima, Mark E. Stearns   +3 more
openaire   +1 more source

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

The Correlation b etween IL - 1β and IL - 10 Levels in Estimating t he Risk of Febrile Seizures

Journal of Tropical Life Science, 2014
Febrile seizures are the most-common form of seizures in children with fever and evidence from clinical and experimental studies suggests the potential role of immune generated products in their genesis.
Gunawan A, Muid M, Sujuti H, Barlianto W, Subandiyah K   +4 more
doaj  

IL-35 and IL-10 Role in The Immune Response of Colorectal Cancer in Iraqi Patients

مجلة الكوفة الطبية
Background: Colorectal cancer (CRC) is presented in the colon and rectum (large intestine) and the disease is expanding worldwide, CRC ranks as the third most common cancer worldwide and cervical cancer is the fourth most common locally.
Saja J. Muhammed, Ahmed Rushdi Abdullah, Nawar Sahib Khalil   +2 more
doaj   +1 more source

Study the relationship between the liver functions and interleukin- 10 in female thalassaemia patients in Kirkuk city

Tikrit Journal of Pure Science, 2019
This study was conducted in thalassaemia center at Azadi Teaching Hospital in Kirkuk city from the  beginning of August 2017 to the end of April 2018. One hundred female subjects were participated in the study (70)  thalassaemic patients and Thirty (30)
Afnan Y. Bakr, Mousa M. Marbut, Ahmed H.AL-Ani   +2 more
doaj   +1 more source

IL-10 Gene Polymorphisms and IL-10 Serum Levels in Patients with Multiple Sclerosis in Lithuania

Brain Sciences, 2022
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with features of demyelination and axonal degeneration at a young age. Genetic factors may play an important role in the development of multiple sclerosis.
Ugne Masilionyte, Greta Gedvilaite, Kriste Kaikaryte, Alvita Vilkeviciute, Loresa Kriauciuniene, Brigita Glebauskiene, Renata Balnyte, Rasa Liutkeviciene   +7 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source