Results 11 to 20 of about 6,985,286 (295)
Role of the IL-23/IL-17 Pathway in Rheumatic Diseases: An Overview
Frontiers in Immunology, 2021 Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, IL-23A (p19) and IL-12/23B (p40), the latter shared with Interleukin-12 (IL-12).
Claudia Schinocca +6 more
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Frontiers in Immunology, 2021 The IL-23/IL-17 axis plays causative roles in the development and progression of systemic lupus erythematosus (SLE). However, it remains unclear if the IL-17RA+ and IL-23R+ T helper (Th) cells populations are associated with the serum IL-17 and IL-23 ...
Aziz Farah Izati +9 more
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Protocol for the safety of brodalumab regarding psychiatric comorbidities in patients with psoriasis
European Psychiatry, 2022 Introduction Brodalumab, an anti-IL17RA monoclonal antibody, is a treatment option for plaque psoriasis related to increased risk of suicidal ideation and behavior, including completed suicide.However, in the literature no causal relationship is ...
O. Pikou +4 more
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Characterization of the IL-17 and CD4+ Th17 Cells in the Clinical Course of Dengue Virus Infections
Viruses, 2020 The aims of this study were to determine the involvement of interleukin 17 (IL-17) and IL-17-producing cells in dengue pathogenesis. Blood samples from dengue virus (DENV)-infected patients were collected on different days after the onset of symptoms ...
Luis Alberto Sánchez-Vargas +9 more
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Role of IL-17 family cytokines in the progression of IPF from inflammation to fibrosis
Military Medical Research, 2022 Idiopathic pulmonary fibrosis (IPF) is a fatal chronic interstitial lung disease with no established treatment and is characterized by progressive scarring of the lung tissue and an irreversible decline in lung function.
Yun-Juan Nie +3 more
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The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Frontiers in Immunology, 2020 Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells.
Taoming Liu +7 more
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Interleukin-17 Links Inflammatory Cross-Talks Between Comorbid Psoriasis and Atherosclerosis
Frontiers in Immunology, 2022 Psoriasis is a chronic, systemic, immune-mediated inflammatory disorder that is associated with a significantly increased risk of cardiovascular disease (CVD).
Yan Wang +5 more
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Barrier immunity and IL-17 [PDF]
Seminars in Immunology, 2009 CD4+ T(H)17 cells display a featured role in barrier immunity. This effector population of T cells is important for clearance of microorganisms but can also promote autoimmunity at barrier sites. Recent work has indicated that these effector cells share a pathway with CD4+ regulatory T cells (T(R) cells) that also have a critical function in barrier ...
Benjamin R, Marks, Joe, Craft
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IL-17 and IL-10 as potential biomarkers for diagnosing periodontitis patients: A Review
Diyala Journal of Medicine, 2023 Background:Evaluation methods for periodontal disorders are continually being refined to yield more precise, reliable, and time-efficient findings.
Maha Abdulsalam Mohammed , +1 more
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IL-17 in obesity and adipogenesis [PDF]
Cytokine & Growth Factor Reviews, 2010 The pro-inflammatory cytokine interleukin (IL)-17 (also known as IL-17) has been associated with induction of tissue inflammation. Obese individuals exhibit many symptoms of chronic low-grade inflammation, suggesting that IL-17 may impact adipose tissue. However, the role of IL-17 in obesity is largely unexplored. Emerging studies indicate that obesity
Mushtaq, Ahmed, Sarah L, Gaffen
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