Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease [PDF]
PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core +4 more sources
The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Pineda, Miguel +7 more
core +4 more sources
Barrier immunity and IL-17 [PDF]
CD4+ T(H)17 cells display a featured role in barrier immunity. This effector population of T cells is important for clearance of microorganisms but can also promote autoimmunity at barrier sites. Recent work has indicated that these effector cells share a pathway with CD4+ regulatory T cells (T(R) cells) that also have a critical function in barrier ...
Benjamin R, Marks, Joe, Craft
openaire +2 more sources
IL-17 in obesity and adipogenesis [PDF]
The pro-inflammatory cytokine interleukin (IL)-17 (also known as IL-17) has been associated with induction of tissue inflammation. Obese individuals exhibit many symptoms of chronic low-grade inflammation, suggesting that IL-17 may impact adipose tissue. However, the role of IL-17 in obesity is largely unexplored. Emerging studies indicate that obesity
Mushtaq, Ahmed, Sarah L, Gaffen
openaire +2 more sources
Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow +38 more
core +1 more source
IL-17 and IL-10 as potential biomarkers for diagnosing periodontitis patients: A Review
Background:Evaluation methods for periodontal disorders are continually being refined to yield more precise, reliable, and time-efficient findings.
Maha Abdulsalam Mohammed , +1 more
doaj +1 more source
The gastrointestinal disease of ruminants is clinically known as Johne's disease (JD) and is caused by Mycobacterium avium subspecies paratuberculosis (MAP).
Justin L. DeKuiper +4 more
doaj +1 more source
Evaluation of serum levels of interleukins 6, 8, 17 and 22 in acne vulgaris: A cross-sectional study
Background: Acne vulgaris (AV) is a chronic, multifactorial, inflammatory skin disease, and it is now becoming increasingly clear that the inflammatory pathway is involved at a very early in the pathogenesis of acne.
Sweta Singh +2 more
doaj +1 more source
IL-17 immunity has been shown to be essential for mucocutaneous protection against Candida albicans in mice and humans. However, mice with defective IL-17 immunity display broader susceptibility, as they are also prone to infections with diverse infectious agents at various sites.
Y, Ling, A, Puel
openaire +2 more sources
Role of interleukin 17 (IL-17) in the inflammatory hypothesis of depression
Depression is one of the most common mental disorders. Despite its high prevalence, the etiopathogenesis of depression is not yet fully understood. Only around 1/3 of depressed patients remit in response to standard antidepressant treatment.
Katarzyna Bliźniewska-Kowalska +3 more
doaj +1 more source

