Results 31 to 40 of about 6,985,286 (295)

Advancing Structure-Based Drug Development: A Rebuild of the IMCA-CAT Beamline at the Advanced Photon Source [PDF]

Structural Dynamics
IMCA-CAT is a structural biology beamline located at the Advanced Photon Source (APS) that caters to pharmaceutical companies for drug discovery. During the 2023-2024 APS-U shutdown, IMCA-CAT undertook a comprehensive beamline upgrade - essentially ...
Melissa Carrillo, John P. Bacik, Erica Duguid, J. Lewis Muir, Clark Williams, Andrew Mayton, Kevin D'Amico, Stephan Ginell, Nathan Brown, Lisa J. Keefe   +9 more
doaj   +1 more source

Bimekizumab for the Treatment of Psoriasis: A Review of the Current Knowledge

Psoriasis: Targets and Therapy, 2022
Angelo Ruggiero, Luca Potestio, Elisa Camela Snr, Gabriella Fabbrocini, Matteo Megna Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, 80131, ItalyCorrespondence: Angelo Ruggiero, Section of ...
Ruggiero A, Potestio L, Camela snr E, Fabbrocini G, Megna M   +4 more
doaj  

Ekstrak Etanol Propolis Menurunkan Kadar IL-17 Serum pada Mencit Balb/C Model Asma Kronik

Majalah Kedokteran Bandung, 2013
Interleukin-17 (IL-17) induces the neutrophil recruitment into the respiratory tract while playing a role in the pathogenesis of asthma and determining the severity of disease.
Sri Hartati Hadinoto, Sarsono , Siti Aisyah, Diding Heri Prasetyo   +3 more
doaj   +1 more source

Characteristic Pattern of IL-17RA, IL-17RB, and IL-17RC in Monocytes/Macrophages and Mast Cells From Patients With Bullous Pemphigoid

Frontiers in Immunology, 2019
Inflammation is largely implicated in bullous pemphigoid (BP), the most frequent skin auto-immune blistering disease. IL-17, essentially IL-17A/F, has been involved in blister formation through regulation of protease production, and its specific serum ...
Stéphane Nesmond, Céline Muller, Richard Le Naour, Richard Le Naour, Manuelle Viguier, Philippe Bernard, Philippe Bernard, Frank Antonicelli, Frank Antonicelli, Sébastien Le Jan   +9 more
doaj   +1 more source

Mini Review: New Treatments in Psoriatic Arthritis. Focus on the IL-23/17 Axis

Frontiers in Pharmacology, 2019
Psoriasis, an inflammatory skin disease, and psoriatic arthritis (PsA), an inflammatory arthritis, share clinical, genetic, and pathogenic factors and may be summed as one disease, the psoriatic disease.
Lazaros I. Sakkas, Efterpi Zafiriou, Dimitrios P. Bogdanos   +2 more
doaj   +1 more source

The role of IL-17 in psoriasis

Journal of Dermatological Treatment, 2014
Psoriasis is a chronic skin condition traditionally believed to involve the Th1 pathway. Recently, the IL-23/Th17/IL-17 pathway has been highlighted in the pathogenesis of psoriasis and other autoimmune inflammatory conditions. From a clinician's perspective, we sought to review the basic science data relevant to IL-17's role in psoriasis pathogenesis ...
Mona, Malakouti, Gabrielle Elena, Brown, Eva, Wang, John, Koo, Ethan C, Levin   +4 more
openaire   +2 more sources

Innate lymphoid cells exhibited IL-17-expressing phenotype in active tuberculosis disease

BMC Pulmonary Medicine, 2021
Background Innate lymphoid cells (ILCs), as an important group of innate immunity, could respond rapidly to Mycobacterium tuberculosis (Mtb) infection.
Linyue Pan, Xiaoli Chen, Xuanqi Liu, Wenjia Qiu, Yunhuan Liu, Weiping Jiang, Yang Zheng, Yan Mou, Wei Xu, Xiangyang Li, Haiyan Ge, Huili Zhu   +11 more
doaj   +1 more source

IL-17 and limits of success

Cellular Immunology, 2019
Interleukin-17 (IL-17) is a potent proinflammatory cytokine that protects a host against fungal and extracellular bacterial infections. On the other hand, excessive or dysregulated production of IL-17 underlines susceptibility to autoimmune disease. Consequently, blocking IL-17 has become an effective strategy for modulating several autoimmune diseases,
Zahra, Omidian, Rizwan, Ahmed, Adebola, Giwa, Thomas, Donner, Abdel Rahim A, Hamad   +4 more
openaire   +3 more sources

IL-27 regulates IL-18 binding protein in skin resident cells [PDF]

, 2012
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M, Miriam Wittmann, Werfel, Thomas, Bachmann, M, Doble, Rosella, Muehl, H, Thomas Werfel, Doble Rosella, Pfeilschifter, Josef (Prof. Dr.), Doble, R, Heiko Mühl, Mühl Heiko, Malte Bachmann, Wittmann Miriam, Pfeilschifter, J, Wittmann, Miriam, Bachmann Malte, Werfel, T, Josef Pfeilschifter, Werfel Thomas, Bachmann, Malte, Mühl, Heiko, Rosella Doble, Pfeilschifter Josef   +23 more
core   +1 more source

Unveiling the IL-17 axis: an immunometabolic bridge between psoriasis and metabolic syndrome

Journal of Dermatological Treatment
Aim of the review Psoriasis is increasingly recognized as a systemic inflammatory disease frequently associated with a cluster of cardiometabolic comorbidities, including obesity, type 2 diabetes, and cardiovascular disease.
Paolo Gisondi, Zeno Fratton, Ralph Vighi da Rosa, Vittoria Bellini, Andrea Carugno   +4 more
doaj   +1 more source