Results 41 to 50 of about 1,561,364 (334)
Journal of Experimental Medicine, 2010 ![Figure][1] APS-I patients harbored autoantibodies against IFN- α , IL-17A, IL-17F, and IL-22. Two new studies suggest why patients with the autoimmune disorder APS-I are susceptible to chronic yeast infections.
openaire +2 more sources
IL-17 Signaling triggers degradation of the constitutive NF-κB inhibitor ABIN-1 [PDF]
, 2017 IL-17 activates NF-κB and induces expression of proinflammatory genes. IL-17 drives disease in autoimmune conditions, and anti–IL-17 Abs have shown impressive success in the clinic.
Amatya, Nilesh +8 more
core +2 more sources
Mucosal adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG in the human colonic mucosa. A proof-of-concept study [PDF]
, 2018 AIM To investigate the adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG (LGG) in the colonic mucosa of healthy and ulcerative colitis (UC) patients, both in vivo and ex vivo in an organ culture model.
Corleto, Vito Domenico +6 more
core +1 more source
The effect of periodontal therapy on IL-17 and IL-23 in Gingival Crevicular Fluid (GCF) of patients with severe periodontitis [PDF]
Caspian journal of dental research, 2013 Introduction: Cytokines are the important factors in the progression of periodontal diseases. The aim of this study was to find out the effect of the first phase of the periodontal therapy on the amount of existing IL-17 and IL-23 in gingival crevicular ...
Marzieh Rohaninasab +3 more
doaj +1 more source
IL-17 signaling components in bivalves: Comparative sequence analysis and involvement in the immune responses [PDF]
, 2015 The recent discovery of soluble immune-regulatory molecules in invertebrates takes advantage of the rapid growth of next generation sequencing datasets. Following protein domain searches in the transcriptomes of 31 bivalve spp.
Gerdol, Marco +4 more
core +1 more source
Commentary: IL-17 in chronic inflammation: From discovery to targeting [PDF]
, 2016 A recent article titled “IL-17 in chronic inflammation: From discovery to targeting,” by Beringer et al. (2016), greatly reviewed the biology of interleukin-17 (IL-17) family members highlighting the contributions of IL-17 cytokines toward diseases and ...
MAIONE, FRANCESCO
core +2 more sources
IL-17: good fear no tears [PDF]
Nature Immunology, 2020 Cytokines are well-known mediators of the immune response, but, recently, pleiotropic roles in the central nervous system have started to be uncovered. It is now shown that IL-17 directly modulates fear behavior in mice.
Rua, Réjane, Pujol, Nathalie
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Arthritis Is Developed in Borrelia-Primed And -Infected Mice Deficient of Interleukin-17 [PDF]
, 2016 Interleukin-17 (IL-17) has been shown to participate in the development of Lyme arthritis in experimental mice. For example, neutralization of IL-17 with antibodies inhibits induction of arthritis in Borrelia-primed and -infected C57BL/6 wild-type mice ...
Kuo, Joseph +4 more
core +1 more source
Interaction of RNA-binding protein HuR and miR-466i regulates GM-CSF expression. [PDF]
, 2017 Granulocyte-macrophage colony-stimulating factor (GM-CSF) produced by T helper 17 (Th17) cells plays an essential role in autoimmune diseases. Transcriptional regulation of Th17 cell differentiation has been extensively studied, but post-transcriptional ...
Adamiak, William +5 more
core +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source