Results 51 to 60 of about 1,561,364 (334)

Two distinct populations of Bovine IL-17+ T-cells can be induced and WC1+IL-17+γδ T-cells are effective killers of protozoan parasites [PDF]

, 2014
IL-17 has emerged as a key player in the immune system, exhibiting roles in protection from infectious diseases and promoting inflammation in autoimmunity.
A Rosbottom, A Rosbottom, AG Andrianarivo, CA Daubenberger, DJ Cua, DJ Williams, DM Estes, F Lopez-Gatius, G Oldenhove, JC Ribot, JS Stumhofer, KB Dobbs, KM Fries, MN Kelly, OE Akilov, R Guiton, RJ Flynn, RM Andrade, SA Geherin   +18 more
core   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization [PDF]

, 2012
Introduction: In recent genome-wide association studies for psoriatic arthritis (PsA) and psoriasis vulgaris, common coding variants in the TRAF3IP2 gene were identified to contribute to susceptibility to both disease entities.
Apel, Maria, Behrens, Frank, Burkhardt, Harald, Böhm, Beate B., Hüffmeier, Ulrike, Reis, André, Uebe, Steffen   +6 more
core   +2 more sources

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi, Paula D. Robinson, Shana Jacobs, L. Lee Dupuis, the International Pediatric Dexamethasone Panel, Sameer Bakhshi, Tiene Bauters, Eva Brack, Simone Cesaro, Claire Fosbrook, Jason Freedman, Tamara MacDonald, Eloise Neumann, Venkatraman Radhakrishnan, Rod Rassekh, Florian Slimano, Johnathan Soggee, Joel Thompson, Marianne van de Wetering, Milena Villarroel, Jasper Wong   +20 more
wiley   +1 more source

Proinflammatory Cytokine Modulates Intracellular Calcium Handling and Enhances Ventricular Arrhythmia Susceptibility

Frontiers in Cardiovascular Medicine, 2021
Background: The mechanism of Interleukin-17 (IL-17) induced ventricular arrhythmia (VA) remains unclear. This study aimed to investigate the effect of intracellular calcium (Cai) handling and VA susceptibility by IL-17.Methods: The electrophysiological ...
Yung-Nan Tsai, Yung-Nan Tsai, Ya-Wen Hsiao, Shien-Fong Lin, Yi-Hsin Chan, Yu-Cheng Hsieh, Yu-Cheng Hsieh, Wei-Hua Tang, Wei-Hua Tang, An-Sheng Lee, Yu-Ting Huang, Hsing-Yuan Li, Tze-Fan Chao, Tze-Fan Chao, Satoshi Higa, Tsu-Juey Wu, Tsu-Juey Wu, Shih-Lin Chang, Shih-Lin Chang, Shih-Ann Chen, Shih-Ann Chen, Shih-Ann Chen, Shih-Ann Chen   +22 more
doaj   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Interleukin-17 Expression in the Barrett’s Metaplasia-Dysplasia-Adenocarcinoma Sequence [PDF]

, 2012
Original Research ArticleIntroduction. This pilot study evaluated the expression of the proinflammatory cytokine IL-17 along the Barrett’s metaplasia-dysplasia-adenocarcinoma sequence by establishing the expression levels of IL-17 in columnar epithelium,
Bannister, Jim R., Deol-Poonia, Ranjeev K., Eccleston, David W., Hughes, Stephen F., Khan, Abdul L.   +4 more
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Serum IL-17 and postmenopausal osteoporosis

مجلة كلية الطب, 2016
Background: Osteoporosis is a bone condition that makes bones thininer and more fragile because of reduced bone density and it puts people at risk of fractures, especially of the hip, spinal vertebrae and wrist. Objective: This study will highlighted the
Tharwa H. AL-Tai
doaj   +1 more source

Interleukin-17 signaling influences CD8+ T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cells

OncoImmunology, 2023
IL-17 immune responses in cancer are controversial, with both tumor-promoting and tumor-repressing effects observed. To clarify the role of IL-17 signaling in cancer progression, we used syngeneic tumor models from different tissue origins. We found that
Constanza Rodriguez, Cintia L. Araujo Furlan, Jimena Tosello Boari, Sabrina N. Bossio, Santiago Boccardo, Laura Fozzatti, Fernando P. Canale, Cristian G. Beccaria, Nicolás G. Nuñez, Danilo G. Ceschin, Eliane Piaggio, Adriana Gruppi, Carolina L. Montes, Eva V. Acosta Rodríguez   +13 more
doaj   +1 more source