Results 71 to 80 of about 67,041,806 (280)
Cell Cycle, 2013 “For every action, there is an equal and opposite reaction.” This axiom is true not only for physical processes, but also for biological activation events, where inhibitory mechanisms are in place to reestablish equilibrium. Nowhere is this more evident than during acute inflammation, where cytokines or pathogen-associated stimuli ramp up a rapid and ...
Garg, Abhishek V, Gaffen, Sarah L
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
Journal of Experimental Medicine, 2010 ![Figure][1] APS-I patients harbored autoantibodies against IFN- α , IL-17A, IL-17F, and IL-22. Two new studies suggest why patients with the autoimmune disorder APS-I are susceptible to chronic yeast infections.
openaire +2 more sources
IL-17 Promotes Murine Lupus [PDF]
The Journal of Immunology, 2014 Abstract The proinflammatory activity of IL-17–producing Th17 cells has been associated with the pathogenesis of several autoimmune diseases. In this article, we provide direct evidence for a role of IL-17 in the pathogenesis of systemic lupus erythematosus (SLE).
Gil, Amarilyo +3 more
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau +8 more
wiley +1 more source
ES-62 protects against collagen-induced arthritis by resetting interleukin-22 towards resolution of inflammation in the joints [PDF]
, 2014 Objective. The parasitic worm–derived immunomodulator ES-62 protects against disease in the mouse collagen-induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin-17 (IL-17) responses. The Th17 associated cytokine
Al-Riyami, Lamyaa +4 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu +8 more
wiley +1 more source
Role of IL-17 in plaque psoriasis: therapeutic potential of ixekizumab
Therapeutics and Clinical Risk Management, 2017 Tessa L Hanley,1 Zenas ZN Yiu2,3 1Fairfield General Hospital, Bury, 2Centre for Dermatology, 3Centre for Pharmacoepidemiology and Drug Safety, Manchester Academic Health Science Centre, Manchester, UK Abstract: Developments in the understanding of the ...
Hanley TL, Yiu ZZN
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