Results 71 to 80 of about 1,561,364 (334)
Frontiers in Immunology, 2018 Neutrophils are known to perform a series of effector functions that are crucial for the innate and adaptive responses, including the synthesis and secretion of a variety of cytokines.
Nicola Tamassia +14 more
doaj +1 more source
Salt, inflammation, IL‐17 and hypertension [PDF]
British Journal of Pharmacology, 2018 Traditionally, arterial hypertension and subsequent end‐organ damage have been attributed to haemodynamic factors, but increasing evidence indicates that inflammation also contributes to the deleterious consequences of this disease. The immune system has evolved to prevent invasion of foreign microorganisms and to promote tissue healing after injury ...
Ulrich O Wenzel +3 more
openaire +2 more sources
Influence of 1 Alpha, 25-Dihydroxyvitamin D3 on T helper 17 cells and related cytokines in systemic lupus erythematosus [PDF]
, 2015 Background: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Emerging data suggests that T helper 17 (Th17) cells play a pathogenic role in SLE and the increased number of these cells correlates with disease activity.
Abdollahi, N. +7 more
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The biological functions of IL-17 in different clinical expressions of Helicobacter pylori-infection [PDF]
, 2015 Helicobacter pylori (H. pylori) infection is regarded as the major cause of various gastric diseases (gastritis, peptic ulcers and gastric cancer) and induces the production of several cytokines.
Azadegan-Dehkordi, Fatemeh. +5 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
The Role of IL-17 and TH17 Cells in the Bone Catabolic Activity of PTH [PDF]
, 2016 Osteoimmunology is field of research dedicated to the study of the interactions between the immune system and bone. Among the cells of the immune system that regulate the skeleton in health and disease are T lymphocytes.
Roberto Pacifici
core +5 more sources
Regulatory effects of C5a on IL-17A, IL-17F, and IL-23
Frontiers in Immunology, 2013 The complement anaphylatoxin, C5a, through binding to its receptors (C5aR or C5L2), has important biological properties for recruitment and activation of phagocytes.
Jamison J. Grailer +2 more
doaj +1 more source
Proinflammatory IL-17 induces iBALT development [PDF]
Cellular & Molecular Immunology, 2011 The development of secondary lymphoid organs (SLOs) and tertiary lymphoid organs (TLOs) share many common mechanisms. Molecules of the tumor necrosis factor family, especially lymphotoxin, and the lymphoid homeostatic chemokines, such as CXCL13, CCL19 and CCL21, play important roles in the development of both SLOs and TLOs.1, 2, 3 This may be ...
Mingzhao, Zhu, Yangxin, Fu
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source
Profile of tildrakizumab-asmn in the treatment of moderate-to-severe plaque psoriasis: evidence to date. [PDF]
, 2018 Plaque psoriasis is an immune-mediated skin disease that affects roughly 3% of adults in the United States. Advances over the past 20 years in understanding the immune-mediated pathophysiology of psoriasis have led to the development of targeted biologic
Beck, Kristen M +3 more
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