Results 81 to 90 of about 1,561,364 (334)

Mycobacterium tuberculosis multi-drug-resistant strain M induces IL-17+ IFNγ- CD4+ T cell expansion through an IL-23 and TGF-β-dependent mechanism in patients with MDR-TB tuberculosis [PDF]

, 2016
We have previously reported that T cells from patients with multidrug-resistant tuberculosis (MDR-TB) express high levels of IL-17 in response to the MDR strain M(Haarlem family) of Mycobacterium tuberculosis (M.tuberculosis).
Balboa, Luciana, Basile, Juan Ignacio, de la Barrera, Silvia Susana, García, A., Gonzalez Montaner, Pablo, Kviatcovsky, Denise, López, Beatriz, Monteserin, Johana, Palmero, Domingo, Ritacco, Gloria Viviana, Romero, María Mercedes, Sabio y García, Carmen Alejandra, Sasiain, María del Carmen, Vescovo, M.   +13 more
core   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Calcium channel Orai1 promotes lymphocyte IL-17 expression and progressive kidney injury [PDF]

, 2019
We hypothesized that the store-operated calcium entry (SOCE) channel, Orai1, participates in the activation of Th17 cells and influences renal injury. In rats, following renal ischemia/reperfusion (I/R), there was a rapid and sustained influx of Orai1 ...
Basile, David P., Mehrotra, Purvi, Neyra, Javier A., Sturek, Michael   +3 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Is interleukin-17 implicated in early knee osteoarthritis pathogenesis as in rheumatoid arthritis?

Egyptian Rheumatology and Rehabilitation, 2022
Background Interleukin-17 (IL-17) is a cytokine that promotes activation of multiple catabolic pathways resulting in cartilage and tissue damage. It has features making it increasingly attractive as a biological marker, especially in rheumatoid arthritis
Hoda M. Abdel-Naby, Sarah S. El-Tawab, Mohamed M. Rizk, Nesrin A. Aboeladl   +3 more
doaj   +1 more source

Evolved to protect, designed to destroy: IL‐17‐producing γδ T cells in infection, inflammation, and cancer [PDF]

, 2021
Rasmus Agerholm, Vasileios Bekiaris
openalex   +1 more source

Insulin and IGF1 enhance IL-17-induced chemokine expression through a GSK3B-dependent mechanism: a new target for melatonin\u27s anti-inflammatory action. [PDF]

, 2013
Obesity is a chronic inflammation with increased serum levels of insulin, insulin-like growth factor 1 (IGF1), and interleukin-17 (IL-17). The objective of this study was to test a hypothesis that insulin and IGF1 enhance IL-17-induced expression of ...
Blask, David E, Brainard, George, Cecil, Kate, MS, Dauchy, Erin M, Dauchy, Robert T, Ge, Dongxia, Hanifin, John P, Hill, Steven M, Liu, Sen, Mao, Lulu, Myers, Leann, Rowan, Brian G, Xiong, Zhenggang, You, Zongbing, Zhang, Qiuyang   +14 more
core   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

IL-17 in obesity and adipogenesis [PDF]

Cytokine & Growth Factor Reviews, 2010
The pro-inflammatory cytokine interleukin (IL)-17 (also known as IL-17) has been associated with induction of tissue inflammation. Obese individuals exhibit many symptoms of chronic low-grade inflammation, suggesting that IL-17 may impact adipose tissue. However, the role of IL-17 in obesity is largely unexplored. Emerging studies indicate that obesity
Mushtaq, Ahmed, Sarah L, Gaffen
openaire   +2 more sources

IL-17 Production from T Helper 17, Mucosal-Associated Invariant T, and γδ Cells in Tuberculosis Infection and Disease. [PDF]

, 2017
IL-17-producing cells have been shown to be important in the early stages of Mycobacterium tuberculosis (Mtb) infection in animal models. However, there are very little data on the role of IL-17 in human studies of tuberculosis (TB).
Coulter, Felicity, Garand, Mathieu, Kampmann, Beate, Lewinsohn, David M, Manning, Declan, Mendy, Joseph, Parrish, Amy, Riley, Eleanor M, Sutherland, Jayne S   +8 more
core   +1 more source