Results 21 to 30 of about 67,041,806 (280)
Immunobiology of IL-17A in human colorectal cancer [PDF]
, 2015 During the last decade tumor infiltration by immune cells has been recognized as a key factor determining clinical outcome. Whereas the presence within tumor tissues of defined lymphocytic populations, including cytotoxic CD8+ T cells and IFN-gamma ...
Amicarella, Francesca
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IL-17/IFN-γ受容体遺伝子ダブル欠損NODマウスにおける糖尿病発症抑制 [PDF]
, 2013 Aims/hypothesis T helper type (Th) 17 cells have been shown to play important roles in mouse models of several autoimmune diseases that have been classified as Th1 diseases. In the NOD mouse, the relevance of Th1 and Th17 is controversial, because single-
厨, 源平
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A case control study on the role of interleukin 17 in the pathogenesis of vitiligo
Pigment International, 2022 Background: Interleukin 17 (IL-17) has recently been implicated in the pathogenesis of vitiligo by many studies but it is unclear whether it has any definitive role in causing depigmentation.
Priyanka Karagaiah +1 more
doaj +1 more source
IL-17 and IL-17-producing cells in protection versus pathology
Nature Reviews Immunology, 2022 IL-17 cytokine family members have diverse biological functions, promoting protective immunity against many pathogens but also driving inflammatory pathology during infection and autoimmunity. IL-17A and IL-17F are produced by CD4+ and CD8+ T cells, γδ T cells, and various innate immune cell populations in response to IL-1β and IL-23, and they mediate ...
openaire +4 more sources
Serum IL-1β and IL-17 levels in patients with COPD: associations with clinical parameters [PDF]
, 2017 Yong Zou,1 Xi Chen,1 Jie Liu,2 Dong bo Zhou,1 Xiao Kuang,1 Jian Xiao,1 Qiao Yu,1 Xiaoxiao Lu,1 Wei Li,1 Bin Xie,1 Qiong Chen1 1Department of Geriatrics, Respiratory Medicine, Xiangya Hospital of Central South University, 2Department of Emergency, The ...
Zhou DB +10 more
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Advancing Structure-Based Drug Development: A Rebuild of the IMCA-CAT Beamline at the Advanced Photon Source [PDF]
Structural DynamicsIMCA-CAT is a structural biology beamline located at the Advanced Photon Source (APS) that caters to pharmaceutical companies for drug discovery. During the 2023-2024 APS-U shutdown, IMCA-CAT undertook a comprehensive beamline upgrade - essentially ...
Melissa Carrillo +9 more
doaj +1 more source
Bimekizumab for the Treatment of Psoriasis: A Review of the Current Knowledge
Psoriasis: Targets and Therapy, 2022 Angelo Ruggiero, Luca Potestio, Elisa Camela Snr, Gabriella Fabbrocini, Matteo Megna Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, 80131, ItalyCorrespondence: Angelo Ruggiero, Section of ...
Ruggiero A +4 more
doaj
IL-23/IL-17 axis and disease activity in systemic lupus erythematosus patients [PDF]
, 2020 Introduction: The latest paradigm proposes that imbalance of Treg and Th17 cells play a significant role in Systemic Lupus Erythematosus (SLE) pathogenesis. The influence of IL-23 and IL-17 on the pathogenesis of SLE remains controversial.
Tri Yanti, Yuliasih, Lita Diah Rahmawati
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IL-17 in the immunopathogenesis of spondyloarthritis [PDF]
Nature Reviews Rheumatology, 2018 Spondyloarthritis (SpA) is a term that refers to a group of inflammatory diseases that includes psoriatic arthritis, axial SpA and nonradiographic axial SpA, reactive arthritis, enteropathic arthritis and undifferentiated SpA. The disease subtypes share clinical and immunological features, including joint inflammation (peripheral and axial skeleton ...
Leonie S. Taams +4 more
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Cytokines of the IL‐17 family in psoriasis [PDF]
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2020 SummaryVarious immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL‐17 family are of particular importance. In addition to IL‐17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL‐17 family also have a proinflammatory effect.
Lauffer, Felix +6 more
openaire +5 more sources