Results 1 to 10 of about 568,316 (160)
Interleukin-22 and acute pancreatitis: A review. [PDF]
Medicine (Baltimore), 2023 Acute pancreatitis (AP) is one of the most common gastrointestinal diseases, and it is divided into 3 types according to its severity:mild acute pancreatitis, moderately severe acute pancreatitis, and severe acute pancreatitis. The mortality in severe acute pancreatitis is approximately 15% to 30% due to multiorgan dysfunction and the lack of specific ...
Fu X, Xiu Z, Xu H.
europepmc +3 more sources
Interleukin-22: Immunobiology and Pathology [PDF]
Annual Review of Immunology, 2015 Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs). Knowledge of IL-22 biology has evolved rapidly since its discovery in 2000, and a role for IL-22 has been identified in numerous tissues, including the intestines, lung,
Jarrod Dudakov, Alan Hanash
exaly +3 more sources
Targeting interleukin-22 for cancer therapy [PDF]
Human Vaccines & Immunotherapeutics, 2018 Interleukin-22 (IL-22) is a member of IL-10 family of cytokines. IL-22 induces proliferative and anti-apoptotic signaling pathways and production of anti-microbial molecules that enhance tissue regeneration and host defense.
Anamarija Markota +2 more
doaj +3 more sources
Protective function of interleukin‐22 in pulmonary fibrosis [PDF]
Clinical and Translational Medicine, 2021 Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive scarring disease with unknown etiology. The evidence of a pathogenic role for transforming growth factor‐beta (TGF‐β) in the development and progression of IPF is overwhelming.
Peiyu Gu +12 more
doaj +2 more sources
Interleukin 22 and its association with neurodegenerative disease activity [PDF]
Frontiers in Pharmacology, 2022 It is worth noting that neuroinflammation is well recognized as a symptom of neurodegenerative diseases (NDs). The regulation of neuroinflammation becomes an attractive focus for innovative ND treatment technologies.
Wenjian Chen +8 more
doaj +2 more sources
The role of interleukin-22 in lung health and its therapeutic potential for COVID-19 [PDF]
Frontiers in Immunology, 2022 Although numerous clinical trials have been implemented, an absolutely effective treatment against coronavirus disease 2019 (COVID-19) is still elusive.
Si Fang +4 more
doaj +2 more sources
Lipid-encapsulated mRNA encoding an extended serum half-life interleukin-22 ameliorates metabolic disease in mice [PDF]
Molecular MetabolismObjective: Interleukin (IL)-22 is a potential therapeutic protein for the treatment of metabolic diseases such as obesity, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease due to its involvement in multiple cellular pathways ...
Susanna Canali +17 more
doaj +2 more sources
Interleukin 18 and interleukin 22 as important immune markers in patients with tuberculosis [PDF]
E3S Web of Conferences, 2023 Tuberculosis (TB) is a lung infection caused by the bacterium Mycobacterium tuberculosis (MTB). TB is a leading cause of death globally, accounting for approximately 1.5 million deaths per year.
Kamoona Firas Mohammad Hussein +1 more
doaj +1 more source
Frontiers in Immunology, 2021 Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE). Our previous studies demonstrated increased serum and renal Interleukin (IL)-22 in LN patients and MRL/lpr mice.
Lingzhen Hu +6 more
doaj +1 more source
Frontiers in Immunology, 2021 Mucosal tissue forms the first line of defense against pathogenic microorganisms. Cellular damage in the mucosal epithelium may induce the interleukin (IL)-22-related activation of many immune cells, which are essential for maintaining the mucosal ...
Yoshie Takahashi +7 more
doaj +1 more source