Results 41 to 50 of about 4,022,531 (291)

Lactobacillus delivery of bioactive interleukin-22 [PDF]

open access: yesMicrobial Cell Factories, 2017
Interleukin-22 (IL-22) plays a prominent role in epithelial regeneration and dampening of chronic inflammatory responses by protecting intestinal stem cells from immune-mediated tissue damage. IL-22 has a considerable therapeutic potential in graft-versus-host disease (GVHD), which is a frequent and challenging complication following allogeneic stem ...
Lin, Yin   +3 more
openaire   +2 more sources

Interleukin-18 [PDF]

open access: yes, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B.   +2 more
core   +1 more source

Interleukin-22 in alcoholic hepatitis and beyond

open access: yesHepatology International, 2020
Alcoholic hepatitis (AH) is a clinical syndrome characterized by jaundice and progressive inflammatory liver injury in patients with a history of prolonged periods of excess alcohol consumption and recent heavy alcohol abuse. Severe AH is a life-threatening form of alcohol-associated liver disease with a high short-term mortality rate around 30-50% at ...
Xiaogang, Xiang   +4 more
openaire   +3 more sources

Biological and pathological activities of interleukin-22 [PDF]

open access: yesJournal of Molecular Medicine, 2016
Interleukin (IL)-22, a member of the IL-10 family, is a cytokine secreted by several types of immune cells including IL-22(+)CD4(+) T cells (Th22) and IL-22 expressing innate leukocytes (ILC22). Recent studies have demonstrated that IL-22 is a key component in mucosal barrier defense, tissue repair, epithelial cell survival, and proliferation ...
Mirna, Perusina Lanfranca   +4 more
openaire   +2 more sources

Restoration of Type 17 immune signaling is not sufficient for protection during influenza-associated pulmonary aspergillosis

open access: yesFrontiers in Immunology
IntroductionInfluenza-associated pulmonary aspergillosis (IAPA) is a severe complication of influenza infection that occurs in critically ill patients and results in higher mortality compared to influenza infection alone.
Aijaz Ahmad   +6 more
doaj   +1 more source

Serum Interleukin-22 as a Marker of Decompensated Liver Cirrhosis and Hepatocellular Carcinoma in Chronic Hepatitis C Virus Patients [PDF]

open access: yesAfro-Egyptian Journal of Infectious and Endemic Diseases
Background and study aim: Chronic liver disease (CLD), when associated with chronic hepatitis C virus (HCV) infection, typically develops into cirrhosis and hepatocellular carcinoma (HCC).
Rania Abou Youssef   +3 more
doaj   +1 more source

Decreased Serum Level of Interleukin-22 Correlates with Hepcidin in Patients with Hidradenitis Suppurativa

open access: yesActa Dermato-Venereologica, 2021
Current understanding of the underlying pathophysiology of hidradenitis suppurativa (HS) links the disease with proinflammatory activation and autoimmune processes.
Malgorzata Ponikowska   +4 more
doaj   +1 more source

Interleukin-22 promotes tumor angiogenesis [PDF]

open access: yesAngiogenesis, 2018
TH17 cells play important yet complex roles in cancer development and progression. We previously reported that TH17 cells and IL-17 mediate resistance to anti-VEGF therapy by inducing recruitment of immunosuppressive and proangiogenic myeloid cells to the tumor microenvironment. Here, we demonstrate that IL-22, a key effector cytokine expressed by TH17
Nicholas J. Protopsaltis   +3 more
openaire   +4 more sources

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]

open access: yes, 2012
BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.
Thomas, GN   +492 more
core   +1 more source

Research advances in understanding the role of interleukin-22 in renal disease

open access: yesLinchuang shenzangbing zazhi, 2022
Interleukin 22(IL-22),a member of IL-10 cytokine superfamily,is dominantly produced by innate lymphoid cells and CD4+ T helper subtypes such as Th17 and Th22 cells.And interleukin-22 receptor (IL-22R) is a dimer composed of IL-22R1 and IL-10R2 subunit.IL-
Zhao Dan   +7 more
doaj  

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